{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T00:31:31Z","timestamp":1774657891133,"version":"3.50.1"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T00:00:00Z","timestamp":1691452800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Innish Otorhinolaryngology - Head and Neck Surgery Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background\/Objectives<\/jats:title>\n                  <jats:p>Patients with obstructive sleep apnoea (OSA) frequently present with some form of upper airway anatomical impairment. Considerable research has been conducted on the role of the structures of the jaw and pharynx in the pathogenesis of OSA; however, the significance of the nose is somewhat unclear. Computed tomography is a widely used imaging modality for assessing the nasal cavity and paranasal sinuses, but only a small amount of the acquired data is used. Our aim was to ascertain whether the size of the cross-sectional areas of the nasal airway, measured from cone beam computed tomography (CBCT) images, is associated with OSA severity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Materials\/Methods<\/jats:title>\n                  <jats:p>A total of 58 patients with OSA, without any major paranasal sinus inflammatory pathology, were included in this register-based study. Patients had previously undergone ambulatory polysomnography and CBCT. The cross-sectional areas of the nasal cavity were measured in CBCT coronal sections. Statistical analyses were performed to determine any correlation between the cross-sectional area measurements and apnoea\u2013hypopnoea index (AHI) or any significant difference in cross-sectional areas between AHI severity groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>No correlation was found between AHI and the smallest, total, or sum of the anterior cross-sectional areas of the nasal airway. Furthermore, there was no statistically significant difference in the cross-sectional areas between patients with the highest and lowest AHI.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions\/Implications<\/jats:title>\n                  <jats:p>The small cross-sectional area of the anterior nasal cavity in patients without any major nasal pathology does not appear to be associated with OSA severity.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejo\/cjad041","type":"journal-article","created":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T13:59:01Z","timestamp":1691503141000},"page":"788-794","source":"Crossref","is-referenced-by-count":7,"title":["Association between nasal airway minimal cross-sectional areas and obstructive sleep apnoea"],"prefix":"10.1093","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8204-4618","authenticated-orcid":false,"given":"Jessi","family":"Makkonen","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Tampere University Hospital , Tampere , Finland"},{"name":"Faculty of Medicine and Health Technology, Tampere University , Tampere , Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olli","family":"Tertti","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Technology, Tampere University , Tampere , Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Rautiainen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Tampere University Hospital , Tampere , Finland"},{"name":"Faculty of Medicine and Health Technology, Tampere University , Tampere , Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saara","family":"Markkanen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Tampere University Hospital , Tampere , Finland"},{"name":"Faculty of Medicine and Health Technology, Tampere University , Tampere , Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olli","family":"Valtonen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Tampere University Hospital , Tampere , Finland"},{"name":"Faculty of Medicine and Health Technology, Tampere University , Tampere , Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaakko","family":"Ormiskangas","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Technology, Tampere University , Tampere , Finland"},{"name":"Faculty of Engineering and Natural Sciences, Automation Technology and Mechanical Engineering Unit, Tampere University , Tampere , Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilkka","family":"Kivek\u00e4s","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Tampere University Hospital , Tampere , Finland"},{"name":"Faculty of Medicine and Health Technology, Tampere University , Tampere , Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timo","family":"Peltom\u00e4ki","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Technology, Tampere University , Tampere , Finland"},{"name":"Department of Oral and Maxillofacial Diseases, Tampere University Hospital , Tampere , Finland"},{"name":"Department of Oral and Maxillofacial Diseases, Kuopio University Hospital , Kuopio , Finland"},{"name":"Faculty of Health Sciences, Institute of Dentistry, University of Eastern Finland , Kuopio , Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,8,8]]},"reference":[{"key":"2024032813062658200_CIT0001","first-page":"456","article-title":"Consequences of sleep-disordered breathing in childhood","volume-title":"Curr Opin Pulm Med","author":"Greene","year":"1997"},{"key":"2024032813062658200_CIT0002","first-page":"744","article-title":"Personalized management approach for OSA","volume-title":"Chest","author":"Carberry","year":"2018"},{"key":"2024032813062658200_CIT0003","first-page":"93","article-title":"Clustering-based characterization of clinical phenotypes in obstructive sleep apnoea using severity, obesity, and craniofacial pattern","volume-title":"Eur J Orthod","author":"An","year":"2020"},{"key":"2024032813062658200_CIT0004","first-page":"101741","article-title":"Anatomical determinants of upper airway collapsibility in obstructive sleep apnea: a systematic review and meta-analysis","volume-title":"Sleep Med Rev","author":"Hartfield","year":"2022"},{"key":"2024032813062658200_CIT0005","first-page":"996","article-title":"Defining phenotypic causes of obstructive sleep apnea. 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