{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T03:07:07Z","timestamp":1790305627181,"version":"4.1.0"},"reference-count":102,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T00:00:00Z","timestamp":1700697600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Dental autotransplantation (DAT) is a biological way of replacing missing or compromised teeth for patients. The techniques often necessitate a multi-disciplinary approach. The prognosis and success of the procedure may be impacted by variable factors in varying degrees.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>Evaluating outcomes and complications of DAT, including prognostic factors using an umbrella review.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Search methods<\/jats:title>\n                  <jats:p>Six databases were searched for all relevant systematic reviews published up to 30 June 2022. No restrictions were applied to language or publication date.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Selection criteria<\/jats:title>\n                  <jats:p>Systematic reviews and meta-analyses of DAT studies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Data collection and analysis<\/jats:title>\n                  <jats:p>Identification, screening, eligibility, and quality assessment using the AMSTAR 2 tool were performed independently by two authors (M.C. and S.A.). Two studies (20%) scored moderate, six studies (60%) scored low, and two studies (20%) scored critically low. Data were analysed using a random effects meta-analysis, and meta-regression was performed to investigate the effect of open and closed apices on the dependent variables. The results were summarised as relative risk ratios.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 310 studies were eligible for inclusion, of which 20 studies were selected for full-text evaluation. Ten systematic reviews were included, 9 of which had a meta-analysis. Overall findings suggest that DAT offers favourable success and survival rates. Meta-regression results indicate that a closed apex increased the proportion of ankylosis and resorption, reduced survival but had no effect on success during the observational period.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Limitations<\/jats:title>\n                  <jats:p>A varying degree of heterogeneity and bias was present in all systematic reviews. The samples of donor teeth included in the systematic reviews also varied morphologically.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>DAT is a technique-sensitive procedure requiring a multidisciplinary team, vigilant case assessment and thorough consideration of the respective prognostic factors involved. Despite methodological limitations reported across studies, DAT shows favourable success and survival rates, with a distinctive advantage of bone induction and soft tissue thickness preservation, and should, therefore, be considered as a viable treatment modality. Standardisation of clinical guidelines and practice are highly recommended.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Registration<\/jats:title>\n                  <jats:p>CRD42020202484.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejo\/cjad067","type":"journal-article","created":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T01:53:09Z","timestamp":1700790789000},"source":"Crossref","is-referenced-by-count":18,"title":["Prognostic factors, outcomes, and complications for dental autotransplantation: an umbrella review"],"prefix":"10.1093","volume":"46","author":[{"given":"Maria","family":"Cremona","sequence":"first","affiliation":[{"name":"Private Practice , St. Paul\u2019s Bay , Malta"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Bister","sequence":"additional","affiliation":[{"name":"Guy\u2019s, King\u2019s and St Thomas Dental Institute , Floor 25, Tower Wing, Great Maze Pond, SE1 9RT, London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martyn","family":"Sherriff","sequence":"additional","affiliation":[{"name":"Bristol Dental Hospital, University of Bristol , Lower Maudlin Street, Bristol BS1 2LY , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Abela","sequence":"additional","affiliation":[{"name":"Health Education England East of England , 2-4 Victoria House, Capital Park, Fulbourn, Cambridge CB21 5XB , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,11,23]]},"reference":[{"key":"2024011114301687100_CIT0001","first-page":"1","article-title":"Tooth auto-transplantation as an alternative treatment option: a literature review","volume-title":"Dental Res J","author":"Nim\u010denko","year":"2013"},{"key":"2024011114301687100_CIT0002","first-page":"1051","article-title":"Autogenic tooth transplantation: a report of ten 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