{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:34:45Z","timestamp":1782927285431,"version":"3.54.5"},"reference-count":80,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T00:00:00Z","timestamp":1758067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Cerebral palsy (CP) results from developmental abnormalities or brain lesions that impair movement, posture, and motor function, thereby affecting skeletal development, including craniofacial structures.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This study aimed to evaluate occlusal characteristics in individuals with and without CP.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Search methods<\/jats:title>\n                  <jats:p>This systematic review followed Meta-Analysis of Observational Studies in Epidemiology guidelines. A comprehensive search was conducted in Embase, PubMed, Web of Science, Ovid, and Scopus, with additional screening of Google Scholar and OpenGrey.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Selection criteria<\/jats:title>\n                  <jats:p>Observational studies were included, and the risk of bias was assessed using Newcastle\u2013Ottawa Scale.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Data collection and analysis<\/jats:title>\n                  <jats:p>Meta-analyses were performed to estimate odds ratios (ORs) with 95% confidence intervals (CIs) and prediction intervals. The GRADE approach was used to evaluate the certainty of the evidence.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of the 584 records identified, 24 cross-sectional studies met the inclusion criteria. Risk-of-bias assessment revealed concerns related to exposure appraisal, nonrespondent characterization, and study comparability. The meta-analysis indicated that individuals with CP had a higher likelihood of Class II malocclusion (OR = 2.56, 95% CI: 1.49\u20134.38, k = 18) and open bite (OR = 4.27, 95% CI: 1.95\u20139.37, k = 9).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Individuals with CP are at increased risk of developing Class II malocclusion and open bite, possibly due to neuromuscular dysfunctions and extrinsic factors. Effective management requires a multidisciplinary approach that addresses both biological and behavioral determinants.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Registration<\/jats:title>\n                  <jats:p>PROSPERO CRD42024551180.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejo\/cjaf070","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:04:23Z","timestamp":1758632663000},"source":"Crossref","is-referenced-by-count":2,"title":["Occlusal features in individuals with cerebral palsy: a systematic review and meta-analysis"],"prefix":"10.1093","volume":"47","author":[{"given":"Anna Carolina Rye Sato","family":"Kimura","sequence":"first","affiliation":[{"name":"Department of Child and Adolescent Oral Health, School of Dentistry, Universidade Federal de Minas Gerais, Avenida Antonio Carlos, 6627, Pampulha, Belo Horizonte, 31270-901 Belo Horizonte ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5270-3950","authenticated-orcid":false,"given":"Victor Zanetti","family":"Drumond","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, Pathology, and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Avenida Antonio Carlos, 6627, Pampulha, Belo Horizonte, 31270-901 Belo Horizonte ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana Gomes","family":"Oliveira","sequence":"additional","affiliation":[{"name":"School of Dentistry, Universidade Federal de Minas Gerais, Avenida Antonio Carlos, 6627, Pampulha, Belo Horizonte, 31270-901 Belo Horizonte ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sic\u00edlia Rezende","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, Pathology, and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Avenida Antonio Carlos, 6627, Pampulha, Belo Horizonte, 31270-901 Belo Horizonte ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo Alves","family":"Mesquita","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, Pathology, and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Avenida Antonio Carlos, 6627, Pampulha, Belo Horizonte, 31270-901 Belo Horizonte ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Alcides Almeida","family":"de Arruda","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis and Pathology, School of Dentistry, Universidade Federal do Rio de Janeiro, Av. 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