{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T01:50:47Z","timestamp":1783734647156,"version":"3.55.0"},"reference-count":40,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2019,11,13]],"date-time":"2019-11-13T00:00:00Z","timestamp":1573603200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To evaluate the result of a novel palatoplasty (minimal incision technique) for closure of an isolated cleft palate (ICP) at 10 and 16 years of age, concerning facial growth, compared to a normal population.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Subjects<\/jats:title>\n                  <jats:p>Treated group: 55 non-syndromic Caucasian children born with an ICP between 1987 and 2001. The children were treated surgically with a one-stage palatoplasty at a mean age of 13 months. Control group: 110 Caucasian children with normal occlusion with no history of clefts or orthodontic intervention.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Method<\/jats:title>\n                  <jats:p>The treated children (25 boys, 30 girls) were matched (gender and age) with the children in the control group. A retrospective evaluation at 10 (mean 10.5) and 16 (mean 16.0) years of age was performed by analysis of lateral cephalograms. Fifteen variables were evaluated. Ninety-nine per cent confidence intervals were calculated. Two-way factorial ANOVA and mixed-model analysis were performed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Treated patients compared to the control group showed: at 10 years of age, smaller mandible (P = 0.001) and reduced posterior upper and total face heights (P \u2264 0.001); at 10 and 16 years of age, a retrognathic (P \u2264 0.001), smaller (P \u2264 0.006) and with an increased posterior inclination of the maxilla (P &lt; 0.001), as well as a retrognathic mandible (P \u2264 0.006).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The craniofacial morphology at 10 and 16 years of age in patients born with an ICP and treated with the minimal incision technique differs compared to the morphology of a normal control group born without a cleft. Retrognathic maxillas and a smaller and posteriorly inclined maxilla were found in the treated group.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejo\/cjz082","type":"journal-article","created":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T08:50:04Z","timestamp":1570092604000},"source":"Crossref","is-referenced-by-count":2,"title":["Facial growth in patients with isolated cleft palate treated with minimal incision technique compared to a normal population\u2014a cephalometric study at 10 and 16 years of age"],"prefix":"10.1093","author":[{"given":"Konstantinos","family":"Parikakis","sequence":"first","affiliation":[{"name":"Division of Orthodontics and Pedodontics, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden"},{"name":"Stockholm Craniofacial Team, Karolinska University Hospital, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ola","family":"Larson","sequence":"additional","affiliation":[{"name":"Stockholm Craniofacial Team, Karolinska University Hospital, Stockholm, Sweden"},{"name":"Department of Plastic and Reconstructive Surgery, Karolinska University Hospital, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9905-4046","authenticated-orcid":false,"given":"Agneta","family":"Karsten","sequence":"additional","affiliation":[{"name":"Division of Orthodontics and Pedodontics, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden"},{"name":"Stockholm Craniofacial Team, Karolinska University Hospital, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,11,13]]},"reference":[{"key":"2019111316324734500_CIT0001","first-page":"239","article-title":"Cephalometric evaluation of facial growth in operated and non-operated individuals with isolated clefts of the palate","volume":"10","author":"Bishara","year":"1973","journal-title":"The 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