{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T12:53:33Z","timestamp":1772888013313,"version":"3.50.1"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:00Z","timestamp":1767830400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Heart failure in paediatric patients is a complex and challenging condition. While heart transplantation is the gold standard for treating end-stage heart failure, limited donor availability necessitates alternative therapies, such as ventricular assist devices (VADs). The HeartMate 3 (HM3) VAD use in adults is well-established, but there is less data regarding outcomes in children. This study aims to evaluate the short-term outcomes of the first paediatric HM3 VAD programme in Saudi Arabia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study involving 15 consecutive paediatric patients treated with HM3 at a single tertiary cardiac centre from 2022 to 2024. Postoperative outcomes included stroke, device thrombosis, driveline infection, hospital mortality, follow-up survival and time to transplantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The cohort had a mean age of 11.07 years, with a predominance of females (67%). Average body surface area was 1.2\u2005m2 (range 0.85\u20131.76\u2005m2). The most frequent diagnosis was dilated cardiomyopathy (n = 13, 87%). The median lengths of ICU and hospital stays were 42 days and 56 days, respectively. The complications included strokes (n = 2, 13%), re-exploration for bleeding (n = 1, 7%), driveline infection (n = 2, 14%) and device thrombosis (n = 1, 7%). In-hospital mortality occurred in two patients. The median follow-up period was 17 months, and 60% (n = 9) of patients underwent successful transplantation. No mortality was reported beyond hospital discharge, and the overall 1-year survival was 87%. The 1-year transplantation-free survival rate was 55%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>HM3 LVADs have favourable safety profiles and survival outcomes in paediatric patients with end-stage heart failure. These findings support HM3\u2019s as a viable option for managing advanced heart failure in the Saudi paediatric population, with further studies warranted to assess long-term outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eschf\/xvaf017","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T09:02:12Z","timestamp":1767862932000},"source":"Crossref","is-referenced-by-count":0,"title":["Short-term outcomes of pediatric HeartMate 3 left ventricular assist device: single center experience"],"prefix":"10.1093","volume":"13","author":[{"given":"Mohannad","family":"Dawary","sequence":"first","affiliation":[{"name":"King Faisal Specialist Hospital & Research Center, Heart Center, Cardiac Surgery , MBC#16, P O BOX 3354, Riyadh 11211 ,","place":["Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimpna","family":"Albert-Brotons","sequence":"additional","affiliation":[{"name":"King Faisal Specialist Hospital & Research Center, Heart Center, Pediatric Cardiology , Riyadh 11211, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7444-7724","authenticated-orcid":false,"given":"Felix W","family":"Tsai","sequence":"additional","affiliation":[{"name":"King Faisal Specialist Hospital & Research Center, Heart Center, Cardiac Surgery , MBC#16, P O BOX 3354, Riyadh 11211 ,","place":["Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,1,8]]},"reference":[{"key":"2026030611565690800_xvaf017-B1","doi-asserted-by":"publisher","first-page":"92","DOI":"10.4103\/1995-705X.192556","article-title":"Heart failure in children","volume":"17","author":"Jayaprasad","year":"2016","journal-title":"Heart Views"},{"key":"2026030611565690800_xvaf017-B2","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/s43057-022-00083-6","article-title":"Preoperative hemodynamics as 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