{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T03:55:00Z","timestamp":1789617300229,"version":"build-2803163510"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100019265","name":"Yuhan Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019265","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hanmi Pharmaceutical"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Residual congestion at discharge is an important risk factor for early readmission and mortality in acute heart failure (AHF); however, it is often underestimated. This study aimed to evaluate the clinical value of oedema index (EI) and phase angle (PA) from bioelectrical impedance analysis (BIA) in assessing residual congestion and predicting short-term outcomes in patients with AHF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A multi-centre registry database from the steady movement with innovating leadership for heart failure (HF) between 2019 and 2023 was analysed. EI and PA were measured using direct segmental multi-frequency BIA device. The worsening heart failure events (WHF) were defined as a composite of HF readmission and all-cause mortality at 90- and 180-days. Receiver operating characteristic analysis determined the EI and PA cut-off values. Logistic regression and Cox proportional hazard analyses were used to assess the associations between BIA parameters and clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 600 patients were included, of whom 360 (60%) were male, with a median age of 72.1 years. Within 180 days, 63 patients (11%) experienced WHFs. EI (odds ratio [OR] 1.83; 95% confidence interval [CI] 1.43\u20132.35 at 90 days, OR 1.76; CI 1.44\u20132.14 at 180 days, all P &amp;lt; .01) and PA (OR 0.93; CI 0.90\u20130.96 at 90 days, OR 0.94; CI 0.91\u20130.96 at 180 days, all P &amp;lt; .01) showed correlation in univariate analysis. EI \u2265 0.4 and PA &amp;lt; 4.5\u00b0 were identified as prognostic thresholds for unfavourable outcomes, with predictive values of 75% (P &amp;lt; .01, sensitivity 83%, and specificity 56%), and 71% (P &amp;lt; .01, sensitivity 81%, and specificity 54%), respectively. Increased EI (adjusted hazard ratio [aHR] 1.71; CI 1.26\u20132.31 at 90 days, aHR 1.64; CI 1.30\u20132.07 at 180 days, all P &amp;lt; .01) and decreased PA (aHR 0.91; CI 0.86\u20130.96 at 90 days, aHR 0.92; CI 0.89\u20130.97 at 180 days, all P &amp;lt; .01) were independently associated with WHFs. Based on the estimated cut-offs, when EI and PA were considered together to classify the high-risk BIA group (EI \u2265 0.4 and PA &amp;lt; 4.5\u00b0), the risk was apparently increased (aHR 6.79; CI 1.71\u201326.93 at 90 days, aHR 3.43; CI 1.41\u20138.32 at 180 days, all P &amp;lt; .05) compared with normal BIA (EI &amp;lt; 0.4 and PA \u2265 4.5\u00b0) group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The EI and PA measured at discharge independently predicted short-term WHFs in patients with AHF. The suggested thresholds for identifying patients at high-risk of residual congestion were EI \u2265 0.4 and PA &amp;lt; 4.5\u00b0. As a non-invasive and accessible modality, BIA holds promise as a complementary tool to established biomarkers for evaluating congestion at discharge.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eschf\/xvaf019","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T20:23:06Z","timestamp":1768854186000},"source":"Crossref","is-referenced-by-count":2,"title":["Residual congestion at discharge assessed by bioelectrical impedance and its prognostic value in acute heart failure: a multi-centre, prospective registry study"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2736-3461","authenticated-orcid":false,"given":"Sangho","family":"Sohn","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Korea University Guro Hospital , Seoul ,","place":["Republic of 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