{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T17:53:26Z","timestamp":1776880406670,"version":"3.51.2"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T00:00:00Z","timestamp":1771804800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100025520","name":"Medical Research Future Fund","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100025520","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Rapid Applied Research Translation"},{"DOI":"10.13039\/501100000925","name":"NHMRC","doi-asserted-by":"publisher","award":["GNT 1136372"],"award-info":[{"award-number":["GNT 1136372"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Heart failure (HF) management guidelines offer evidence-based recommendations but can be difficult to implement in primary care. This randomized controlled trial evaluated a multifaceted intervention to improve adherence to pharmacological and nonpharmacological HF management guidelines in primary care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Patients hospitalized with HF were randomized 1:1 to an intervention or control group. The intervention group received guideline-based inpatient education, a postdischarge plan including referral to cardiac rehabilitation (CR) and scheduled general practitioner follow-ups at 1 and 4 weeks, and 3 months, supported by a cardiologist-approved medication titration plan. The control group received usual care. The primary outcome, measured at 6 months, was adherence to five recommended treatments: (i) ACEI\/ARB\/ARNI \u226550% target dose, (ii) beta blocker \u226550% target dose, (iii) MRA at any dose, (iv) anticoagulation for atrial fibrillation, and (v) CR referral. Adherence was compared using chi-squared tests and logistic regression.<\/jats:p>\n                    <jats:p>Of 225 participants (25% female), a greater proportion in the intervention group achieved the primary outcome (61.8% vs. 28.7%; P &amp;lt; .01). The unadjusted odds ratio showed that the intervention group was 6.27 times more likely to achieve the outcome compared to the control group (95% confidence interval [CI], 3.35\u201311.76, P &amp;lt; .01). This difference was driven by higher prescription rates of ACEI\/ARB\/ARNI and beta blocker, and higher referral rates to CR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Hospital-based support for HF-management in primary care improved adherence to pharmacological and non-pharmacological components of guideline-recommended care. Greater implementation of transitional care processes of this nature has the potential to improve clinical outcomes for patients with HF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eschf\/xvag061","type":"journal-article","created":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T12:31:14Z","timestamp":1771763474000},"source":"Crossref","is-referenced-by-count":0,"title":["Primary care Adherence to Heart failure guidelines in post-discharge, evaluation &amp; routine management (PATHFINDER): a randomized controlled trial"],"prefix":"10.1093","volume":"13","author":[{"given":"Andrew","family":"Maiorana","sequence":"first","affiliation":[{"name":"Curtin School of Allied Health, Curtin University, Bentley , Western Australia 6102 ,","place":["Australia"]},{"name":"Allied Health Department, Fiona Stanley Hospital , Murdoch, Western Australia 6150 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