{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T11:37:03Z","timestamp":1792841823924,"version":"4.5.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"vor","delay-in-days":13,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Herlev and Gentofte Hospitals Interne Fond","id":[{"id":"https:\/\/ror.org\/051dzw862","id-type":"ROR","asserted-by":"crossref"}]},{"name":"CARDIO-HGH"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Sex differences in chronic heart failure are well established, but corresponding differences in acute heart failure (AHF), particularly in multimodal imaging findings and short-term recovery, remain incompletely characterized.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this prospective observational study, 567 adults hospitalized with AHF underwent clinical assessment, laboratory testing, transthoracic echocardiography, and lung ultrasound during the early in-hospital phase (median 2 days after admission) and 1\u20133 months after discharge. The primary endpoint was the composite of all-cause mortality or heart failure readmission within 180 days.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 567 patients (mean age 78.2 \u00b1 11.6 years), 248 (43.7%) were female. Females were older and more frequently had atrial fibrillation and hypertension, whereas males more frequently had dyslipidaemia and ischaemic heart disease. Females more frequently presented with palpitations and peripheral oedema, whereas males more frequently reported chest pain. During the early in-hospital assessment, females had higher left ventricular ejection fraction (38% vs 35%, P &amp;lt; .001), higher absolute global longitudinal strain (10.5 \u00b1 4.7% vs 9.7 \u00b1 4.4%, P = .04), lower left ventricular mass index (113 vs 136\u2005g\/m2, P &amp;lt; .001), and higher relative wall thickness (.51 vs .47, P = .002). Males had a higher lung ultrasound B-line count (5 [1\u201312] vs 2 [0\u20139], P = .003). Among patients completing follow-up, improvements in cardiac function and congestion were similar between sexes. No statistically significant sex differences were observed in the 180-day composite outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Females and males hospitalized with AHF exhibited distinct clinical presentations and imaging profiles during the early in-hospital assessment. Among patients completing follow-up, short-term recovery was similar between sexes, with no statistically significant sex differences in 180-day clinical outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eschf\/xvag235","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T11:35:37Z","timestamp":1788867337000},"source":"Crossref","is-referenced-by-count":0,"title":["Sex differences in acute heart failure: clinical presentation, imaging findings, and short-term recovery"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4087-7511","authenticated-orcid":false,"given":"Ayat","family":"Khoraizat","sequence":"first","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filip Soeskov","family":"Davidovski","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2879-8862","authenticated-orcid":false,"given":"Caroline","family":"Espersen","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Adam","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Hikmat","family":"Al-Rubai","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Ramadan","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton","family":"Stanchev","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emil","family":"Durukan","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristoffer Grundtvig","family":"Skaarup","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ema","family":"Rastoder","sequence":"additional","affiliation":[{"name":"Respiratory Medicine Section, Department of Medicine, Copenhagen University Hospital\u2014Herlev and Gentofte , Copenhagen ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Dons","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofie","family":"B\u00f8gh-S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie Ottilie Hjorts\u00f8","family":"Janner","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline L\u00f8kke","family":"Bjerregaard","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nino Emanuel","family":"Landler","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"Sengel\u00f8v","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie Inge-Marie Helene","family":"Borchsenius","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa Steen","family":"Duus","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrine Feldballe","family":"Bernholm","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam Femerling","family":"Langhoff","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mats Christian H\u00f8jbjerg","family":"Lassen","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4231-0299","authenticated-orcid":false,"given":"Jacob","family":"Christensen","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Marie Reimer","family":"Jensen","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla Ikast","family":"Ottosen","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manan","family":"Pareek","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6064-062X","authenticated-orcid":false,"given":"Emil","family":"Wolsk","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4271-2466","authenticated-orcid":false,"given":"Morten","family":"Schou","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tor","family":"Biering-S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark"},{"name":"Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Herlev and Gentofte , Gentofte Hospitalsvej 1, 2900 Hellerup ,","place":["Denmark"]},{"name":"Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen N ,","place":["Denmark"]},{"name":"Steno Diabetes Center Copenhagen ,","place":["Denmark"]},{"name":"Department of Cardiology, Copenhagen University Hospital\u2014Rigshospitalet , Copenhagen ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,9]]},"reference":[{"key":"2026102406464520700_xvag235-B1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.15420\/cfr.2016:25:2","article-title":"Global public health burden of heart failure","volume":"3","author":"Savarese","year":"2017","journal-title":"Card Fail Rev"},{"key":"2026102406464520700_xvag235-B2","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1007\/s11897-017-0351-y","article-title":"Acute heart failure: definition, classification and epidemiology","volume":"14","author":"Kurmani","year":"2017","journal-title":"Curr Heart Fail Rep"},{"key":"2026102406464520700_xvag235-B3","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1016\/j.jchf.2023.06.028","article-title":"Global variations according to sex in patients hospitalized for heart failure in the REPORT-HF registry","volume":"11","author":"Tromp","year":"2023","journal-title":"JACC Heart Fail"},{"key":"2026102406464520700_xvag235-B4","doi-asserted-by":"publisher","first-page":"3859","DOI":"10.1093\/eurheartj\/ehz835","article-title":"Sex differences in heart failure","volume":"40","author":"Lam","year":"2019","journal-title":"Eur Heart J"},{"key":"2026102406464520700_xvag235-B5","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1002\/ejhf.67","article-title":"Sex-specific cardiovascular structure and function in heart failure with preserved ejection fraction","volume":"16","author":"Gori","year":"2014","journal-title":"Eur J Heart Fail"},{"key":"2026102406464520700_xvag235-B6","doi-asserted-by":"publisher","first-page":"1530","DOI":"10.1016\/j.jacc.2022.02.013","article-title":"Sex-based differences in heart failure","volume":"79","author":"Khan","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"2026102406464520700_xvag235-B7","doi-asserted-by":"publisher","first-page":"1669","DOI":"10.1002\/ejhf.3284","article-title":"Differences in presentation, diagnosis and management of heart failure in women. A scientific statement of the Heart Failure Association of the ESC","volume":"26","author":"Rosano","year":"2024","journal-title":"Eur J Heart Fail"},{"key":"2026102406464520700_xvag235-B8","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.ejim.2024.09.013","article-title":"The assessment, interpretation and implementation of lung ultrasound examinations in heart failure: current evidence and gaps in knowledge","volume":"130","author":"Palazzuoli","year":"2024","journal-title":"Eur J Intern Med"},{"key":"2026102406464520700_xvag235-B9","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1093\/eurheartj\/ehv745","article-title":"Detection and prognostic value of pulmonary congestion by lung ultrasound in ambulatory heart failure patients","volume":"37","author":"Platz","year":"2016","journal-title":"Eur Heart J"},{"key":"2026102406464520700_xvag235-B10","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1002\/ejhf.1771","article-title":"Sex-related differences in contemporary biomarkers for heart failure: a review","volume":"22","author":"Suthahar","year":"2020","journal-title":"Eur J Heart Fail"},{"key":"2026102406464520700_xvag235-B11","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1093\/eurheartj\/ehaa071","article-title":"The association of long-term outcome and biological sex in patients with acute heart failure from different geographic regions","volume":"41","author":"Motiej\u016bnait\u0117","year":"2020","journal-title":"Eur Heart J"},{"key":"2026102406464520700_xvag235-B12","doi-asserted-by":"publisher","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","article-title":"2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"42","author":"McDonagh","year":"2021","journal-title":"Eur Heart J"},{"key":"2026102406464520700_xvag235-B13","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1093\/ehjci\/jev014","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"16","author":"Lang","year":"2015","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2026102406464520700_xvag235-B14","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1016\/j.jchf.2019.07.008","article-title":"Lung ultrasound in acute heart failure","volume":"7","author":"Platz","year":"2019","journal-title":"JACC Heart Fail"},{"key":"2026102406464520700_xvag235-B15","doi-asserted-by":"publisher","first-page":"1784","DOI":"10.1002\/ehf2.13300","article-title":"Sex differences in congestive markers in patients hospitalized for acute heart failure","volume":"8","author":"Espersen","year":"2021","journal-title":"ESC Heart Fail"},{"key":"2026102406464520700_xvag235-B16","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1007\/s00392-020-01642-9","article-title":"Ultrasound indices of congestion in patients with acute heart failure according to body mass index","volume":"109","author":"Palazzuoli","year":"2020","journal-title":"Clin Res Cardiol"},{"key":"2026102406464520700_xvag235-B17","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1093\/ehjacc\/zuaf067","article-title":"The intersection of obesity and acute heart failure: cardiac structure and function and congestion across BMI categories","volume":"14","author":"B\u00f8gh-S\u00f8rensen","year":"2025","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"2026102406464520700_xvag235-B18","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1002\/clc.23073","article-title":"Sex-related differences in left ventricular diastolic function and arterial elastance during admission in patients with heart failure with preserved ejection fraction: the PURSUIT HFpEF study","volume":"41","author":"Hoshida","year":"2018","journal-title":"Clin Cardiol"},{"key":"2026102406464520700_xvag235-B19","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1093\/eurjhf\/hft115","article-title":"Sex-specific acute heart failure phenotypes and outcomes from PROTECT","volume":"15","author":"Meyer","year":"2013","journal-title":"Eur J Heart Fail"},{"key":"2026102406464520700_xvag235-B20","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1016\/j.jchf.2020.12.011","article-title":"Sex differences in clinical course and patient-reported outcomes among patients hospitalized for heart failure","volume":"9","author":"Blumer","year":"2021","journal-title":"JACC Heart Fail"},{"key":"2026102406464520700_xvag235-B21","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/j.jchf.2019.03.011","article-title":"Sex-based differences in heart failure across the ejection fraction Spectrum","volume":"7","author":"Stolfo","year":"2019","journal-title":"JACC Heart Fail"}],"container-title":["ESC Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eschf\/advance-article-pdf\/doi\/10.1093\/eschf\/xvag235\/71010481\/xvag235.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eschf\/article-pdf\/13\/5\/xvag235\/71010481\/xvag235.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eschf\/article-pdf\/13\/5\/xvag235\/71010481\/xvag235.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T10:46:53Z","timestamp":1792838813000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eschf\/article\/doi\/10.1093\/eschf\/xvag235\/8789418"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,27]]},"references-count":21,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,9,9]]},"published-print":{"date-parts":[[2026,8,27]]}},"URL":"https:\/\/doi.org\/10.1093\/eschf\/xvag235","relation":{},"ISSN":["2055-5822"],"issn-type":[{"value":"2055-5822","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,10]]},"published":{"date-parts":[[2026,8,27]]},"article-number":"xvag235"}}