{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T09:23:29Z","timestamp":1771838609738,"version":"3.50.1"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T00:00:00Z","timestamp":1767312000000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Cervical arterial dissections (CeAD) can involve either single (sCeAD) or multiple (mCeAD) arteries. Whether the involvement of a single versus multiple arteries is associated with outcomes remains unclear. We aimed to study associations between the number of affected arteries and clinical, imaging and outcome parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>Patients with CeAD from the STOP-CAD multicenter registry study were included. Clinical, imaging, treatment and outcome parameters were compared between patients with sCeAD and mCeAD. Regression analyses were performed to identify associations with multi-arteries involvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, 3858 STOP-CAD patients were included in this analysis and 443 (11.5%) had mCeAD. The presence of mCeAD was associated with age (adjusted odds ratio [aOR] 95% confidence intervals [95% CI] 0.99; (0.98\u20131.00)), female sex (aOR 1.5; 95% CI 1.17\u20131.91), recent upper respiratory infection (aOR 2.25; 95% CI 1.55\u20133.27), presence of connective tissue disease (aOR 3.11; 95% CI 2.32\u20134.17), severe arterial stenosis (aOR 1.95; 95% CI 1.95\u20132.58), intracranial extension (aOR 1.47; 95% CI 1.04\u20132.09), vertebral artery involvement (aOR 2.50; 95% CI 1.94\u20133.22) and presence of dissecting aneurysm (aOR 2.59; 95% CI 1.95\u20133.42). In adjusted analyses, mCeAD was not associated with clinical outcomes (ischemic stroke, mortality, and sICH; all p\u2009&amp;gt;\u20090.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>mCeAD does not appear to increase risk of subsequent stroke as compared to sCAD despite baseline risk factors suggestive of vasculopathy. mCeAD patients who did develop a stroke presented with milder strokes and less often had vessel occlusions compared to those with sCeAD. The presence of mCeAD did not impact outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/esj\/23969873251383313","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T11:01:23Z","timestamp":1768906883000},"source":"Crossref","is-referenced-by-count":0,"title":["Characteristics of patients with extracranial cervical artery dissections involving more than a single vessels: A subgroup analysis of STOP-CAD"],"prefix":"10.1093","volume":"11","author":[{"given":"Issa","family":"Metanis","sequence":"first","affiliation":[{"name":"Department of Neurology , Hadassah-Hebrew University Medical Center, Jerusalem ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Favour","family":"Akpokiere","sequence":"additional","affiliation":[{"name":"Department of Neurology , Brown University Medical Center, Providence, RI ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liqi","family":"Shu","sequence":"additional","affiliation":[{"name":"Department of Neurology , Brown University Medical Center, Providence, RI ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoel","family":"Schwartzmann","sequence":"additional","affiliation":[{"name":"Department of Neurology , Hadassah-Hebrew University Medical Center, Jerusalem ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8228-1347","authenticated-orcid":false,"given":"Hamza","family":"Jubran","sequence":"additional","affiliation":[{"name":"Department of Neurology , Hadassah-Hebrew University Medical Center, Jerusalem ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kateryna","family":"Antonenko","sequence":"additional","affiliation":[{"name":"Department of Neurology , Inselspital University 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T","family":"Engelter","sequence":"additional","affiliation":[{"name":"Department Rehabilitation and Neurology , University Department of Geriatric Medicine FELIX PLATTER, University of Basel, Basel ,","place":["Switzerland"]},{"name":"Neurology and Stroke Center , University Hospital Basel, Depart. of Clinical Research, University Basel, Basel ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7744-2796","authenticated-orcid":false,"given":"Josefin E","family":"Kaufmann","sequence":"additional","affiliation":[{"name":"Department Rehabilitation and Neurology , University Department of Geriatric Medicine FELIX PLATTER, University of Basel, Basel ,","place":["Switzerland"]},{"name":"Neurology and Stroke Center , University Hospital Basel, Depart. of Clinical Research, University Basel, Basel ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher Kenan","family":"Traenka","sequence":"additional","affiliation":[{"name":"Department Rehabilitation and Neurology , University Department of Geriatric Medicine FELIX PLATTER, University of Basel, Basel ,","place":["Switzerland"]},{"name":"Neurology and Stroke Center , University Hospital Basel, Depart. of Clinical Research, University Basel, Basel ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2277-5950","authenticated-orcid":false,"given":"Joao Pedro","family":"Marto","sequence":"additional","affiliation":[{"name":"Department of Neurology , Hospital de Egas Moniz, Centro Hospitalar Lisboa Ocidental, Lisbon ,","place":["Portugal"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Romoli","sequence":"additional","affiliation":[{"name":"Department of Neurosciences , Bufalini Hospital, Cesena 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