{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T21:14:51Z","timestamp":1778706891898,"version":"3.51.4"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:00:00Z","timestamp":1778630400000},"content-version":"vor","delay-in-days":12,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2023-ER-1006-02"],"award-info":[{"award-number":["2023-ER-1006-02"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Soonchunhyang University Research Fund"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The ATTENTION (0\u201312\u00a0hours) and BAOCHE (6\u201324\u00a0hours) trials demonstrated the efficacy of endovascular treatment (EVT) for basilar artery occlusion (BAO) in highly selected populations, but real-world generalizability remains uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>We analyzed patients with acute BAO presenting within 24\u00a0hours of last known well from a nationwide, multicenter, prospective stroke registry. Patients were categorised as ATTENTION-eligible, BAOCHE-eligible, and ineligible based on clinical and neuroimaging criteria from both trials. The primary outcome was the distribution of 3-month modified Rankin Scale (mRS). Secondary outcomes included 3-month mRS of 0\u20133 and 0\u20132, 90-day mortality, and symptomatic hemorrhagic transformation. Inverse probability of treatment weighting was applied to adjust for baseline differences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 49,471 patients with acute ischemic stroke, 2.0% (n\u00a0=\u00a01012) had BAO. Of these, 24% met ATTENTION-criteria, 6% met BAOCHE-criteria, and 72% were ineligible for both. Endovascular treatment was performed in 75%, 59%, and 43% of these groups, respectively. In ATTENTION-eligible patients, EVT was associated with more favourable mRS distribution (cOR, 1.73; 95% CI, 1.03\u20132.93) and lower 3-month mortality (RR, 0.52; 95% CI, 0.33\u20130.80). In BAOCHE-eligible patients, adjusted models did not reach statistical significance due to limited sample size. Among ineligible patients, EVT was associated with lower mortality (RR, 0.77; 95% CI, 0.60\u20130.99). Symptomatic haemorrhage rates did not differ across groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Most BAO patients were ineligible for pivotal EVT trials, and eligibility for the more stringent BAOCHE criteria was particularly rare in real-world practice. Endovascular treatment was associated with reduced mortality even in ineligible patients. These findings highlight the practical limitations of current trial-based selection criteria and support broader application of EVT for BAO.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/esj\/aakag031","type":"journal-article","created":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T21:00:36Z","timestamp":1778706036000},"source":"Crossref","is-referenced-by-count":0,"title":["Real-world effectiveness of thrombectomy for basilar artery occlusion: lessons beyond the ATTENTION and BAOCHE trials"],"prefix":"10.1093","volume":"11","author":[{"given":"Jeong-Yoon","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Neurology, Soonchunhyang University Hospital Seoul, Soonchunhyang University College of Medicine , Seoul ,","place":["Republic of Korea"]},{"name":"Department of Translational Medicine, Graduate School of Medicine, Seoul National University College of Medicine , Seoul ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo-Hyun","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Neurology, Soonchunhyang University Hospital Seoul, Soonchunhyang University College of Medicine , Seoul ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyungbok","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurology, Soonchunhyang University Hospital Seoul, Soonchunhyang University College of Medicine , Seoul ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo Joo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurology, Daejeon Eulji Medical Center, Eulji University School of medicine , Daejeon ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyusik","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Nowon Eulji Medical Center, Eulji University School of Medicine , Seoul ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Kwan","family":"Cha","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dong-A University Hospital , Busan ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyung Seok","family":"Guk","sequence":"additional","affiliation":[{"name":"Division of Intensive Care Medicine, Department of Neurosurgery and Neurology, Seoul National University Bundang Hospital , Seongnam ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nakhoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital , Seongnam ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonguk","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital , Seongnam ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Do Yeon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital , Seongnam ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun Yup","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital , Seongnam ,","place":["Republic of 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Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Kyo","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Neurology, Seoul Medical Center , Seoul ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tai Hwan","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Neurology, Seoul Medical Center , Seoul ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doo Hyuk","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Neurology, Yeungnam University Medical Center , Daegu ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurology, Yeungnam University Medical Center , Daegu ,","place":["Republic of 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,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ho Geol","family":"Woo","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kyung Hee University Hospital , Seoul ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Hyuk","family":"Heo","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kyung Hee University Hospital , Seoul ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8073-9304","authenticated-orcid":false,"given":"Juneyoung","family":"Lee","sequence":"additional","affiliation":[{"name":"Korea University, BK21FOUR R&E Center for Learning Health Systems, Department of Biostatistics , Seoul ,","place":["Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8194-3462","authenticated-orcid":false,"given":"Ji 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