{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T13:19:38Z","timestamp":1793020778780,"version":"4.5.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:00:00Z","timestamp":1784592000000},"content-version":"vor","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005971","name":"German Heart Foundation","doi-asserted-by":"publisher","award":["F\/11\/23"],"award-info":[{"award-number":["F\/11\/23"]}],"id":[{"id":"10.13039\/501100005971","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Atrial fibrillation (AF) burden, the time spent in AF, is increasingly investigated. Data on its characteristics and temporal patterns during early in-hospital telemetry after ischaemic stroke remain limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>Continuous ECG telemetry was analysed in consecutive patients with MRI-confirmed ischaemic stroke and AF admitted between October 2020 and January 2023 in this observational retrospective cohort trial. Peak AF burden within any 24-h window was categorised as low (\u22641\u00a0h), medium (&amp;gt;1\u20136\u00a0h), high (&amp;gt; 6\u00a0h) or no recorded AF episodes. Associations with clinical and imaging features were assessed using multivariable regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 392 patients with AF-related stroke (median monitoring duration 68\u00a0h, median AF burden 12.0\u00a0h), AF burden was low in 30 (7.7%), medium in 68 (17.3%), high in 193 (49.2%) and 101 (25.8%) had no recorded episodes. Left-insular stroke was negatively associated with high AF burden (aOR 0.38, 95% CI, 0.15\u20130.84, P\u00a0&amp;lt;\u00a0.05). There was a signal towards a positive association with right-insular stroke (aOR 1.75, 95% CI, 0.90\u20133.41, P\u00a0=\u00a0.09). The laterality difference persisted in continuous-scale analyses. First AF episodes clustered in the early evening among low-burden patients, with early morning episodes least common across all groups. Among patients with known stroke onset (n\u00a0=\u00a0102), 49 exhibited AF confined to the first 48\u00a0h.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>AF burden varies widely during early in-hospital monitoring after ischaemic stroke and seems to differ according to insular lesion laterality. Our findings are hypothesis-generating and highlight the need for integrating lesion location, circadian and arrhythmia dynamics to characterise AF burden after stroke.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/esj\/aakag079","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T18:01:09Z","timestamp":1784656869000},"source":"Crossref","is-referenced-by-count":1,"title":["Atrial fibrillation burden during in-patient cardiac monitoring after acute ischaemic stroke"],"prefix":"10.1093","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8990-262X","authenticated-orcid":false,"given":"Markus G","family":"Klammer","sequence":"first","affiliation":[{"name":"Center for Stroke Research Berlin (CSB) , Berlin ,","place":["Germany"]},{"name":"Department of Neurology with Experimental Neurology, Charit\u00e9 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and HumboldtUniversit\u00e4t zu Berlin , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Reimann","sequence":"additional","affiliation":[{"name":"Center for Stroke Research Berlin (CSB) , Berlin ,","place":["Germany"]},{"name":"Department of Neurology with Experimental Neurology, Charit\u00e9 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and HumboldtUniversit\u00e4t zu Berlin , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oskar","family":"Richter","sequence":"additional","affiliation":[{"name":"Center for Stroke Research Berlin (CSB) , Berlin ,","place":["Germany"]},{"name":"Department of Neurology with Experimental Neurology, Charit\u00e9 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and HumboldtUniversit\u00e4t zu Berlin , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Lieschke","sequence":"additional","affiliation":[{"name":"Center for Stroke Research Berlin (CSB) , Berlin ,","place":["Germany"]},{"name":"Department of Neurology with Experimental Neurology, Charit\u00e9 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and HumboldtUniversit\u00e4t zu Berlin , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Stengl","sequence":"additional","affiliation":[{"name":"Center for Stroke Research Berlin (CSB) , Berlin ,","place":["Germany"]},{"name":"Department of Neurology with Experimental Neurology, Charit\u00e9 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and HumboldtUniversit\u00e4t zu Berlin , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Hellwig","sequence":"additional","affiliation":[{"name":"Center for Stroke Research Berlin (CSB) , Berlin ,","place":["Germany"]},{"name":"Department of Neurology with Experimental Neurology, Charit\u00e9 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and HumboldtUniversit\u00e4t zu Berlin , Berlin ,","place":["Germany"]},{"name":"Berlin Institute of Health at Charit\u00e9, Universit\u00e4tsmedizin Berlin, BIH Biomedical Innovation Academy, BIH Charit\u00e9 Clinician Scientist Program , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Schoels","sequence":"additional","affiliation":[{"name":"Center for Stroke Research Berlin (CSB) , Berlin ,","place":["Germany"]},{"name":"Department of Neurology with Experimental Neurology, Charit\u00e9 Universit\u00e4tsmedizin Berlin, corporate 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Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and HumboldtUniversit\u00e4t zu Berlin , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7233-5342","authenticated-orcid":false,"given":"Andreas","family":"Meisel","sequence":"additional","affiliation":[{"name":"Center for Stroke Research Berlin (CSB) , Berlin ,","place":["Germany"]},{"name":"Department of Neurology with Experimental Neurology, Charit\u00e9 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and HumboldtUniversit\u00e4t zu Berlin , Berlin ,","place":["Germany"]},{"name":"Neuroscience Clinical Research Center, Charit\u00e9 Universit\u00e4tsmedizin Berlin , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfram","family":"Doehner","sequence":"additional","affiliation":[{"name":"Center for Stroke Research Berlin (CSB) , Berlin ,","place":["Germany"]},{"name":"German Center for Cardiovascular Research (DZHK), partner site Berlin , Berlin ,","place":["Germany"]},{"name":"Berlin Institute of Health Center for Regenerative Therapies, Charit\u00e9 - Universit\u00e4tsmedizin Berlin , Berlin ,","place":["Germany"]},{"name":"Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charit\u00e9 , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian H","family":"Nolte","sequence":"additional","affiliation":[{"name":"Center for Stroke Research Berlin (CSB) , Berlin ,","place":["Germany"]},{"name":"Department of Neurology with Experimental Neurology, Charit\u00e9 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and HumboldtUniversit\u00e4t zu Berlin , Berlin ,","place":["Germany"]},{"name":"Berlin Institute of Health , Berlin ,","place":["Germany"]},{"name":"German Center for Cardiovascular Research 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