{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T08:24:12Z","timestamp":1787127852412,"version":"build-2736575974"},"reference-count":4,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:00:00Z","timestamp":1787011200000},"content-version":"vor","delay-in-days":17,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,5]]},"DOI":"10.1093\/esj\/aakag095","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:25:30Z","timestamp":1787066730000},"source":"Crossref","is-referenced-by-count":0,"title":["Net water uptake and lesion extent as joint expressions of ischaemic injury: a comment on the TENSION secondary analysis"],"prefix":"10.1093","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9630-6949","authenticated-orcid":false,"given":"Apostolos","family":"Safouris","sequence":"first","affiliation":[{"name":"Stroke Unit, Metropolitan Hospital , Piraeus ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1631-7056","authenticated-orcid":false,"given":"Wim H","family":"van Zwam","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine, Maastricht University Medical Center , Maastricht ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,8,18]]},"reference":[{"key":"2026081903261105900_ref1","doi-asserted-by":"publisher","first-page":"aakag055","DOI":"10.1093\/esj\/aakag055","article-title":"Oedema reduction mediates thrombectomy benefit in large core stroke: secondary analysis of the TENSION trial","volume":"11","author":"Broocks","year":"2026","journal-title":"Eur Stroke J"},{"key":"2026081903261105900_ref2","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1177\/0271678X19848505","article-title":"Ischemic lesion growth in acute stroke: water uptake quantification distinguishes between edema and tissue infarct","volume":"40","author":"Broocks","year":"2020","journal-title":"J Cereb Blood Flow Metab"},{"key":"2026081903261105900_ref3","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1515\/em-2012-0010","article-title":"Mediation analysis with multiple mediators","volume":"2","author":"VanderWeele","year":"2014","journal-title":"Epidemiol Methods"},{"key":"2026081903261105900_ref4","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1002\/ana.26587","article-title":"Mediation of successful reperfusion effect through infarct growth and cerebral edema: a pooled, patient-level analysis of EXTEND-IA trials and SELECT prospective cohort","volume":"93","author":"Sarraj","year":"2023","journal-title":"Ann Neurol"}],"container-title":["European Stroke Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/esj\/article-pdf\/11\/8\/aakag095\/70685421\/aakag095.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/esj\/article-pdf\/11\/8\/aakag095\/70685421\/aakag095.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T07:26:18Z","timestamp":1787124378000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/esj\/article\/doi\/10.1093\/esj\/aakag095\/8763870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":4,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8,5]]}},"URL":"https:\/\/doi.org\/10.1093\/esj\/aakag095","relation":{},"ISSN":["2396-9873","2396-9881"],"issn-type":[{"value":"2396-9873","type":"print"},{"value":"2396-9881","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,8]]},"published":{"date-parts":[[2026,8]]},"article-number":"aakag095"}}