{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T19:26:03Z","timestamp":1787253963994,"version":"build-2736575974"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Endovascular thrombectomy (EVT) is the standard of care for LVO stroke; however, rapid workflow is critical for a beneficial outcome. Artificial intelligence (AI)-supported imaging tools, such as Brainomix 360 Stroke, may improve the efficiency of acute stroke imaging and reduce treatment delays. We evaluated the effects of regional implementation of Brainomix 360 Stroke in a high-volume system with routine use of perfusion imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>We conducted a retrospective register-based cohort study of consecutive patients treated with EVT at Sahlgrenska University Hospital from June 2021 to May 2024. Patients outside the Region V\u00e4stra G\u00f6taland prehospital area or aged under 18\u00a0years were excluded. The study period was divided into pre-implementation, learning and established periods following Brainomix 360 Stroke introduction. Primary organisational outcomes were time from non-contrast brain CT (NCCT) to CT perfusion map availability (CT-to-perfusion-map-availability) and from NCCT to groin puncture (CT\u2013puncture). Clinical outcomes included early neurological improvement (\u22654 points on the NIHSS or a score of 0\u20131 at 24\u00a0h) and favourable functional outcome (mRS scores 0\u20132 or return to pre-stroke mRS at 90\u00a0days).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 970 EVT patients were included. Adjusted median CT\u2013puncture significantly decreased from 47\u00a0min pre-implementation to 36 and 35\u00a0min in the learning and established periods, respectively. Adjusted median CT-to-perfusion-map-availability significantly decreased from 7\u00a0min pre-implementation to 6\u00a0min in the established period. In subgroup analyses of primary stroke centres (PSCs), results were similar while no significant differences were found in subgroup analyses of the comprehensive stroke centre. No significant differences were observed in clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion and conclusion<\/jats:title>\n                    <jats:p>Implementation of an AI-supported imaging decision-making tool was associated with significant reductions in key workflow times, largely attributable to decreased times at PSCs in the region.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/esj\/aakag098","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T18:40:13Z","timestamp":1787251213000},"source":"Crossref","is-referenced-by-count":0,"title":["Implementation of an AI-supported decision-making tool in a high-volume stroke system with routine perfusion imaging"],"prefix":"10.1093","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5428-9995","authenticated-orcid":false,"given":"Adrian","family":"Karlsson","sequence":"first","affiliation":[{"name":"Department of Radiology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg , Gothenburg ,","place":["Sweden"]},{"name":"Section of Diagnostic and Interventional Neuroradiology, Department of Radiology, Sahlgrenska University Hospital , Region V\u00e4stra G\u00f6taland, Gothenburg ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1225-7359","authenticated-orcid":false,"given":"Erik","family":"Cadeborn","sequence":"additional","affiliation":[{"name":"Section of Diagnostic and Interventional Neuroradiology, Department of Radiology, Sahlgrenska University Hospital , Region V\u00e4stra G\u00f6taland, Gothenburg ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9291-3151","authenticated-orcid":false,"given":"Malin","family":"Woock","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg , Gothenburg ,","place":["Sweden"]},{"name":"Department of Neurology, Sahlgrenska University Hospital , Region V\u00e4stra G\u00f6taland, Gothenburg ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9142-0737","authenticated-orcid":false,"given":"Arne","family":"Allardt","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg , Gothenburg ,","place":["Sweden"]},{"name":"Department of Neurology, Sahlgrenska University Hospital , Region V\u00e4stra G\u00f6taland, Gothenburg ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8746-1771","authenticated-orcid":false,"given":"Katarina","family":"Jood","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg , Gothenburg ,","place":["Sweden"]},{"name":"Department of Neurology, Sahlgrenska University Hospital , Region V\u00e4stra G\u00f6taland, Gothenburg ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9023-3363","authenticated-orcid":false,"given":"Isabella","family":"Bj\u00f6rkman-Burtscher","sequence":"additional","affiliation":[{"name":"Department of Radiology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg , Gothenburg ,","place":["Sweden"]},{"name":"Section of Diagnostic and Interventional Neuroradiology, Department of Radiology, Sahlgrenska University Hospital , Region V\u00e4stra G\u00f6taland, Gothenburg ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6610-7802","authenticated-orcid":false,"given":"Alexandros","family":"Rentzos","sequence":"additional","affiliation":[{"name":"Department of Radiology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg , Gothenburg ,","place":["Sweden"]},{"name":"Section of Diagnostic and Interventional Neuroradiology, Department of Radiology, Sahlgrenska University Hospital , Region V\u00e4stra G\u00f6taland, Gothenburg ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,8,20]]},"reference":[{"key":"2026082014400615000_ref1","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1056\/NEJMoa1706442","article-title":"Thrombectomy 6 to 24 hours after stroke with 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