{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T17:18:18Z","timestamp":1788283098101,"version":"build-2803163510"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":31,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Japan Society for the Promotion of Science (JSPS) KAKENHI","award":["24K19537"],"award-info":[{"award-number":["24K19537"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Distal occlusion tracker (DOT) signs on immediate post-interventional flat-panel detector CT (FDCT) can identify residual vessel occlusions underestimated by conventional angiography after endovascular thrombectomy (EVT). However, whether these FDCT-detected occlusions are associated with tissue-level outcomes remains unclear. We investigated whether FDCT-augmented reperfusion grading better reflects tissue imaging outcomes than operator-assessed reperfusion grading in patients with ischaemic stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>We retrospectively analysed EVT-treated patients with expanded thrombolysis in cerebral infarction (TICI) \u2265 2b who underwent post-interventional FDCT and follow-up MRI. DOT signs were defined as punctiform or tubular hyperdensities on FDCT. Final infarct volume (FIV) was segmented using follow-up DWI. Reperfusion status was categorised as incomplete (TICI 2b) or near-complete\/complete (TICI 2c\/3) based on FDCT-augmented TICI assessed by a core laboratory or operator-graded TICI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 200 patients, the median FIV was 20.0\u00a0mL (IQR, 5.9\u201374.6), and DOT signs were identified in 86 (43.0%). Operator-graded TICI classified 61 patients (30.5%) as having incomplete reperfusion, compared with 72 patients (36.0%) by FDCT-augmented TICI; 17 patients were reclassified. Compared with near-complete\/complete reperfusion, incomplete reperfusion by FDCT-augmented TICI was associated with larger FIV (\u03b2\u00a0=\u00a024.0\u00a0mL; 95% CI, 3.6\u201344.4), whereas operator-defined incomplete reperfusion was not (\u03b2\u00a0=\u00a012.2\u00a0mL; 95% CI, \u22129.5 to 33.9). The model incorporating FDCT-augmented TICI explained slightly more variance in FIV than the model incorporating operator-graded TICI (adjusted R2 0.256 vs 0.239).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>FDCT-augmented reperfusion assessment may provide additional tissue-relevant information after EVT by identifying residual vessel occlusions associated with larger FIV.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/esj\/aakag104","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:40:09Z","timestamp":1788280809000},"source":"Crossref","is-referenced-by-count":0,"title":["Refining reperfusion assessment with flat-panel detector CT: association with final infarct volume after endovascular thrombectomy"],"prefix":"10.1093","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9632-2164","authenticated-orcid":false,"given":"Junpei","family":"Koge","sequence":"first","affiliation":[{"name":"Department of Comprehensive Strokology, Fujita Health University School of Medicine , Toyoake ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Department of Comprehensive Strokology, Fujita Health University School of Medicine , Toyoake ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichiro","family":"Suyama","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University School of Medicine , Toyoake ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Comprehensive Strokology, Fujita Health University School of Medicine , Toyoake ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyonori","family":"Kuwahara","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University School of Medicine , Toyoake ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiji","family":"Fujiwara","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University School of Medicine , Toyoake ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daijiro","family":"Kojima","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University School of Medicine , Toyoake ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsunori","family":"Mase","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University School of Medicine , Toyoake ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiho","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University School of Medicine , Toyoake ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saki","family":"Hyoudou","sequence":"additional","affiliation":[{"name":"Department of Radiology, Fujita Health University Hospital , Toyoake ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syouta","family":"Naito","sequence":"additional","affiliation":[{"name":"Department of Radiology, Fujita Health University Hospital , Toyoake ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuyoshi","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Radiology, Fujita Health University Hospital , Toyoake 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