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This study aimed to develop a strategy to reduce the concentration of 13 POPs found in soil. The compounds studied were: \u03b1-hexachlorocyclohexane (\u03b1-HCH), \u03b2-hexachlorocyclohexane (\u03b2-HCH), \u03b3-hexachlorocyclohexane (\u03b3-HCH), heptachlor, heptachlor epoxide, aldrin, dieldrin, endrin, 2,4\u2032-dichloro diphenyl dichloroethane (2,4\u2032DDD), 4,4\u2032-dichlorodiphenyl dichloroethane (4,4\u2032DDD), 4,4\u2032-dichlorodiphenyl dichloroethylene (4,4\u2032DDE), 2,4\u2032-dichlorodiphenyl trichloroethane (2,4\u2032DDT), and 4,4\u2032-dichlorodiphenyl trichloroethane (4,4\u2032DDT). Additionally, to support the possible source distribution of POPs, a characterization of their presence in plasma from free-ranging dogs was conducted. The analyzed plasma samples revealed average concentrations of 4,4\u2032DDT (92.20\u2009ng\/g lipid), 4,4\u2032 DDD (124.11\u2009ng\/g lipid), and 4,4\u2032DDE (149.64\u2009ng\/g lipid), indicating that the area occupied by Tekchem plant is a source point of DDT compounds, which are bioavailable, suggesting a possible exposure to environmental. The remediation strategy involved the use of molasses and zero-valent iron (ZVI) at three different concentrations in subsurface extracted soil (up to 30\u2009cm deep). This soil was homogenized and characterized, initially showing a concentration of \u2211POPs of 6,078.34\u2009mg\/kg; the 4,4\u2032DDT concentration is particularly noteworthy at 4,200\u2009mg\/kg. Remediation treatment results demonstrated that the 1% ZVI (w\/w) application achieved a maximum reduction of \u2211POPs by 96.45%. However, statistical analysis revealed no significant differences between the treatments applied. Although differences were noted when comparing the treatments with the control group and among the individual treatments, the conclusion suggests that selecting a specific agent for reducing POPs at the study site should be guided by a comprehensive cost-benefit analysis.<\/jats:p>","DOI":"10.1093\/etojnl\/vgaf157","type":"journal-article","created":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T18:10:51Z","timestamp":1755886251000},"page":"555-563","source":"Crossref","is-referenced-by-count":1,"title":["Assessment of persistent organic pollutants and a remediation proposal at a former pesticide plant in Salamanca, Mexico"],"prefix":"10.1093","volume":"45","author":[{"given":"Israel","family":"Castro Ram\u00edrez","sequence":"first","affiliation":[{"name":"Environmental Science Department, DICIVA, University of Guanajuato , Irapuato,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Ram\u00edrez 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