{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T19:32:55Z","timestamp":1793734375477,"version":"4.6.1"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Australian Research Council and the Anindilyakwa Land Council","award":["LP160100736"],"award-info":[{"award-number":["LP160100736"]}],"id":[{"id":"https:\/\/ror.org\/05mmh0f86","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Groote Eylandt, Australia, is an island of international conservation significance as well as the site of one of the world\u2019s largest manganese (Mn) mines. Endangered northern quolls (Dasyurus hallucatus) living near active Mn mining sites on Groote Eylandt accumulate Mn at higher concentrations in the hair, testes, and brain than do animals living far from the mine. However, little is known about the potential developmental effects of Mn exposure on the tissues of quolls or other marsupials, and marsupial histology and ecotoxicology are relatively understudied. We examined relationships between exposure to Mn and other toxic metals and the histological endpoints of quolls and northern brown bandicoots (Isoodon macrourus). Male quolls (n\u2009=\u200918) and bandicoots (n\u2009=\u20099) were live trapped near and far from mining activities, euthanized, and dissected for target tissues (liver, lung, muscles [bicep, quadricep, skull], olfactory bulb), which were preserved in formalin for histology. Tissues were prepared with hematoxylin and eosin staining and analyzed with Leica imaging software. Although we did not find differences in most tissues between animals collected near and far from the mine, we found that Mn exposure was associated with altered muscle histomorphology of quolls, potentially affecting their ability to find food and avoid predators. Our results showed clear differences between the muscle histology of quolls and bandicoots. Given the ecological importance of Groote Eylandt and the conservation needs of species such as quolls and bandicoots, information on exposure to contaminants and effects on health and development is critical to successful management, including environmental remediation.<\/jats:p>","DOI":"10.1093\/etojnl\/vgag216","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T14:21:20Z","timestamp":1786371680000},"page":"3340-3350","source":"Crossref","is-referenced-by-count":0,"title":["Manganese exposure and histology of northern quolls (\n                    <i>Dasyurus hallucatus<\/i>\n                    ) and northern brown bandicoots (\n                    <i>Isoodon macrourus<\/i>\n                    ) on Groote Eylandt, Australia"],"prefix":"10.1093","volume":"45","author":[{"given":"Elise M","family":"Contreras","sequence":"first","affiliation":[{"name":"Department of Biological Sciences, Northern Arizona University , Flagstaff, AZ,","place":["United 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