{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T23:55:13Z","timestamp":1782777313276,"version":"3.54.5"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2020,3,2]],"date-time":"2020-03-02T00:00:00Z","timestamp":1583107200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Hatter Institute for Cardiovascular Research in African"},{"DOI":"10.13039\/501100007112","name":"University of Cape Town","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007112","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Medical Research Council SA"},{"DOI":"10.13039\/501100001321","name":"National Research Foundation SA","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Maurice Hatter Foundation"},{"DOI":"10.13039\/501100011725","name":"SERVIER Laboratories","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,3,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The principle of \u2018sick individuals vs. sick population\u2019, a concept pioneered by Geoffrey Rose 35\u2009years ago, is particularly applicable to heart failure (HF). This perspective article summarizes and expands on the Geoffrey Rose lecture given at the European Society of Cardiology meeting held in conjunction with the World Congress of Cardiology, in Paris, 2019. This article focuses on the fact that, clearly, HF not only affects a large spectrum of the population globally, but it occurs in all ages and equally in both genders. Heart failure, in most parts of the world, is clearly not a disease of the elderly. There are multiple and complex pathways leading to HF which include various risk factors (including communicable diseases and exposure to indoor and environmental pollutants), poverty and overcrowding, as well as sub-optimal access to health care systems due to socioeconomic inequities. Reflecting on Geoffrey Rose\u2019s concept 35\u2009years later motivates us to confront our global responsibility to address the population distribution of risk factors more effectively, instead of focusing solely on interventions that target high-risk individuals.<\/jats:p>\n               <jats:p\/>","DOI":"10.1093\/eurheartj\/ehaa084","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T12:10:57Z","timestamp":1580299857000},"page":"1298-1306","source":"Crossref","is-referenced-by-count":24,"title":["Heart failure can affect everyone: the ESC Geoffrey Rose lecture"],"prefix":"10.1093","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8272-0911","authenticated-orcid":false,"given":"Karen","family":"Sliwa","sequence":"first","affiliation":[{"name":"Department of Medicine, Faculty of Health Sciences, Hatter Institute for Cardiovascular Research in Africa , University of Cape Town, 3 Anzio road, Observatory 7925, Cape Town, South Africa"},{"name":"Soweto Cardiovascular Research Unit, University of the Witwatersrand , 1 Jan Smuts Ave, Johannesburg 2000, South Africa"},{"name":"Mary McKillop Institute , Melbourne, 215 Spring St, Melbourne, Victoria, 3000, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,3,2]]},"reference":[{"key":"2022101805470335500_ehaa084-B1","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1093\/ije\/14.1.32","article-title":"Sick individuals and sick populations","volume":"14","author":"Rose","year":"1985","journal-title":"Int J Epidemiol"},{"key":"2022101805470335500_ehaa084-B2","volume-title":"The Strategy of Preventative Medicine","author":"Rose","year":"1992"},{"key":"2022101805470335500_ehaa084-B3","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/j.jacc.2013.11.053","article-title":"The global health and economic burden of hospitalizations for heart failure: lessons learned from hospitalized 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