{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T22:26:37Z","timestamp":1793831197010,"version":"4.6.1"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"45","license":[{"start":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T00:00:00Z","timestamp":1600992000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The aim of this study was to identify determinants of in-hospital and mid-term outcomes after isolated tricuspid valve surgery (ITVS) and more specifically the impact of tricuspid regurgitation (TR) mechanism and clinical presentation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Among 5661 consecutive adult patients who underwent a tricuspid valve (TV) surgery at 12 French tertiary centres in 2007\u20132017 collected from a mandatory administrative database, we identified 466 patients (8% of all tricuspid surgeries) who underwent an ITVS. Most patients presented with advanced disease [47% in New York Heart Association (NYHA) III\/IV, 57% with right-sided heart failure (HF) signs]. Tricuspid regurgitation was functional in 49% (22% with prior left-sided heart valve surgery and 27% isolated) and organic in 51% (infective endocarditis in 31% and other causes in 20%). In-hospital mortality and major complications rates were 10% and 31%, respectively. Rates of survival and survival free of HF readmission were 75% and 62% at 5\u2009years. Patients with functional TR incurred a worse in-hospital mortality than those with organic TR (14% vs. 6%, P\u2009=\u20090.004), but presentation was more severe. Independent determinants of outcomes were NYHA Class III\/IV [odd ratios (OR)\u2009=\u20092.7 (1.2\u20136.1), P\u2009=\u20090.01], moderate\/severe right ventricular dysfunction [OR\u2009=\u20092.6 (1.2\u20135.8), P\u2009=\u20090.02], lower prothrombin time [OR\u2009=\u20090.98 (0.96\u20130.99), P\u2009=\u20090.008], and with borderline statistical significance, right-sided HF signs [OR\u2009=\u20092.4 (0.9\u20136.5), P\u2009=\u20090.06] while TR mechanism was not [OR\u2009=\u20090.7 (0.3\u20131.8), P\u2009=\u20090.88].<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Isolated TV surgery was associated with high mortality and morbidity, both in hospital and during follow-up, predicted by the severity of the presentation but not by TR mechanism. Our results suggest that TV intervention should be performed earlier in the course of the disease.<\/jats:p>\n                    <jats:p\/>\n                  <\/jats:sec>","DOI":"10.1093\/eurheartj\/ehaa643","type":"journal-article","created":{"date-parts":[[2020,7,23]],"date-time":"2020-07-23T15:12:56Z","timestamp":1595517176000},"page":"4304-4317","source":"Crossref","is-referenced-by-count":298,"title":["Isolated tricuspid valve surgery: impact of aetiology and clinical presentation on outcomes"],"prefix":"10.1093","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1338-3007","authenticated-orcid":false,"given":"Julien","family":"Dreyfus","sequence":"first","affiliation":[{"name":"Cardiology Department, Centre Cardiologique du Nord , 32-36 rue des moulins g\u00e9meaux, Saint-Denis 93200, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Flagiello","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery and Transplantation, Louis Pradel Cardiovascular Hospital, Claude Bernard University , 59 Boulevard Pinel, 69500 Bron, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3437-3994","authenticated-orcid":false,"given":"Baptiste","family":"Bazire","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bichat Claude Bernard Hospital , 46 Rue Henri Huchard, 75018 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Eggenspieler","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Nancy-Brabois , 29 Avenue du Mar\u00e9chal de Lattre de Tassigny, 54035 Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1492-2447","authenticated-orcid":false,"given":"Florence","family":"Viau","sequence":"additional","affiliation":[{"name":"Cardiology Department, APHM, La Timone Hospital , 278 Rue Saint-Pierre, 13005 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Riant","sequence":"additional","affiliation":[{"name":"Cardiology Department, Expert Valve Center, Henri Mondor Hospital , 51 Avenue du Mar\u00e9chal de Lattre de Tassigny, 94010 Cr\u00e9teil, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yannick","family":"Mbaki","sequence":"additional","affiliation":[{"name":"Cardiology Department, CHU de RENNES, LTSI UMR1099, INSERM, Universit\u00e9 de Rennes-1 , 2 Rue Henri le Guilloux, 35000 Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohann","family":"Bohbot","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Amiens University Hospital , 1 Rue du Professeur Christian Cabrol, 80054 Amiens, France"},{"name":"UR UPJV 7517, Jules Verne University of Picardie , 51 Boulevard de Ch\u00e2teaudun, 80000 Amiens, 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France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9344-1814","authenticated-orcid":false,"given":"Martin","family":"Nicol","sequence":"additional","affiliation":[{"name":"Cardiology Department, Centre Cardiologique du Nord , 32-36 rue des moulins g\u00e9meaux, Saint-Denis 93200, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabien","family":"Doguet","sequence":"additional","affiliation":[{"name":"Service de chirurgie cardiovasculaire et thoracique, CHU Charles Nicolle , 37 Boulevard Gambetta, 76000 Rouen, France"},{"name":"Normandie Univ, Unirouen , INSERM U1096, Rouen 76000, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Cardiology Department, Centre Cardiologique du Nord , 32-36 rue des moulins g\u00e9meaux, Saint-Denis 93200, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augustin","family":"Coisne","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology and Echocardiography \u2013 Heart Valve Clinic , CHU Lille, 2 Avenue Oscar Lambret, 59000 Lille, France"},{"name":"Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille , U1011 - EGID, Lille F-59000, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Le Tourneau","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Nantes, CHU de Nantes, CNRS, INSERM, l\u2019institut du thorax , Nantes F-44000, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8310-4512","authenticated-orcid":false,"given":"Yoan","family":"Lavie-Badie","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rangueil University Hospital , 9 Place Lange, 31300 Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7867-3668","authenticated-orcid":false,"given":"Christophe","family":"Tribouilloy","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Amiens University Hospital , 1 Rue du Professeur Christian Cabrol, 80054 Amiens, France"},{"name":"UR UPJV 7517, Jules Verne University of Picardie , 51 Boulevard de Ch\u00e2teaudun, 80000 Amiens, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9083-1582","authenticated-orcid":false,"given":"Erwan","family":"Donal","sequence":"additional","affiliation":[{"name":"Cardiology Department, CHU de RENNES, LTSI UMR1099, INSERM, Universit\u00e9 de Rennes-1 , 2 Rue Henri le Guilloux, 35000 Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9382-3660","authenticated-orcid":false,"given":"Jacques","family":"Tomasi","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, CHU de RENNES, Universit\u00e9 de Rennes-1 , 2 Rue Henri le Guilloux, 35000 Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3899-9983","authenticated-orcid":false,"given":"Gilbert","family":"Habib","sequence":"additional","affiliation":[{"name":"Cardiology Department, APHM, La Timone Hospital , 278 Rue Saint-Pierre, 13005 Marseille, France"},{"name":"Aix Marseille Univ, IRD, APHM, MEPHI, IHU-M\u00e9diterran\u00e9e Infection , 19-21 Boulevard Jean Moulin, 13005 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4129-5784","authenticated-orcid":false,"given":"Christine","family":"Selton-Suty","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Nancy-Brabois , 29 Avenue du Mar\u00e9chal de Lattre de Tassigny, 54035 Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Raffoul","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, 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