{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T16:25:22Z","timestamp":1792686322844,"version":"4.5.0"},"reference-count":67,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T00:00:00Z","timestamp":1605657600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Chronic obstructive pulmonary disease (COPD) is highly prevalent among patients with atrial fibrillation (AF), shares common risk factors, and adds to the overall morbidity and mortality in this population. Additionally, it may promote AF and impair treatment efficacy. The prevalence of COPD in AF patients is high and is estimated to be \u223c25%. Diagnosis and treatment of COPD in AF patients requires a close interdisciplinary collaboration between the electrophysiologist\/cardiologist and pulmonologist. Differential diagnosis may be challenging, especially in elderly and smoking patients complaining of unspecific symptoms such as dyspnoea and fatigue. Routine evaluation of lung function and determination of natriuretic peptides and echocardiography may be reasonable to detect COPD and heart failure as contributing causes of dyspnoea. Acute exacerbation of COPD transiently increases AF risk due to hypoxia-mediated mechanisms, inflammation, increased use of beta-2 agonists, and autonomic changes. Observational data suggest that COPD promotes AF progression, increases AF recurrence after cardioversion, and reduces the efficacy of catheter-based antiarrhythmic therapy. However, it remains unclear whether treatment of COPD improves AF outcomes and which metric should be used to determine COPD severity and guide treatment in AF patients. Data from non-randomized studies suggest that COPD is associated with increased AF recurrence after electrical cardioversion and catheter ablation. Future prospective cohort studies in AF patients are needed to confirm the relationship between COPD and AF, the benefits of treatment of either COPD or AF in this population, and to clarify the need and cost-effectiveness of routine COPD screening.<\/jats:p>\n               <jats:p\/>","DOI":"10.1093\/eurheartj\/ehaa822","type":"journal-article","created":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T12:01:19Z","timestamp":1601553679000},"page":"532-540","source":"Crossref","is-referenced-by-count":112,"title":["Chronic obstructive pulmonary disease and atrial fibrillation: an interdisciplinary perspective"],"prefix":"10.1093","volume":"42","author":[{"given":"Sami O","family":"Simons","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Maastricht University Medical Centre , P. Debyelaan 25, 6229 HX Maastricht, the Netherlands"},{"name":"Division of Respiratory & Age-related Health, Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Universiteitssingel 40, 6229 ER \u00a0Maastricht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5951-4239","authenticated-orcid":false,"given":"Adrian","family":"Elliott","sequence":"additional","affiliation":[{"name":"Centre for Heart Rhythm Disorders, University of Adelaide and Royal Adelaide Hospital , 1 Port Road, SA 5000 Adelaide, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Sastry","sequence":"additional","affiliation":[{"name":"Academic Sleep Centre CIRO , Hornerheide 1, 6085 NM Horn, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4326-9256","authenticated-orcid":false,"given":"Jeroen M","family":"Hendriks","sequence":"additional","affiliation":[{"name":"Centre for Heart Rhythm Disorders, University of Adelaide and Royal Adelaide Hospital , 1 Port Road, SA 5000 Adelaide, Australia"},{"name":"Institute of Health, Medicine and Caring Sciences, Link\u00f6ping University , Campus US, SE 581 83 Link\u00f6ping, Sweden"},{"name":"Caring Futures Institute, College of Nursing and Health Sciences, Flinders University , GPO Box 2100, SA 5001 Adelaide, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4408-722X","authenticated-orcid":false,"given":"Michael","family":"Arzt","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, Centre of Sleep Medicine, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2581-070X","authenticated-orcid":false,"given":"Michiel","family":"Rienstra","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9700 RB, Groningen, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan M","family":"Kalman","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Royal Melbourne Hospital and Department of Medicine, University of Melbourne , Grattan St Parkville, 3050 Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9301-8127","authenticated-orcid":false,"given":"Hein","family":"Heidbuchel","sequence":"additional","affiliation":[{"name":"University of Antwerp and Antwerp University Hospital , Drie Eikenstraat 655, 2650 Antwerp, Belgium"},{"name":"Faculty of Medicine and Life Sciences, Hasselt University , Martelarenlaan 42, 3500 Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5565-3311","authenticated-orcid":false,"given":"Stanley","family":"Nattel","sequence":"additional","affiliation":[{"name":"Department of Medicine, Montreal Heart Institute and Universit\u00e9 de Montr\u00e9al , 5000 Rue B\u00e9langer, QC H1T 1C8, Montr\u00e9al, Canada"},{"name":"Department of Pharmacology and Therapeutics, McGill University , 3649 Promenade Sir-William-Osler, QC H3A 1A3, Canada"},{"name":"Institute of Pharmacology, West German Heart and Vascular Center, Faculty of Medicine, University Duisburg-Essen , Hufelandstra\u00dfe 55, 45147 Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2032-0557","authenticated-orcid":false,"given":"Geertjan","family":"Wesseling","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Maastricht University Medical Centre , P. Debyelaan 25, 6229 HX Maastricht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Schotten","sequence":"additional","affiliation":[{"name":"University Maastricht, Cardiovascular Research Institute Maastricht (CARIM) , Universiteitssingel 50, 6229 ER Maastricht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle C","family":"van Gelder","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9700 RB, Groningen, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1633-6356","authenticated-orcid":false,"given":"Frits M E","family":"Franssen","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Maastricht University Medical Centre , P. Debyelaan 25, 6229 HX Maastricht, the Netherlands"},{"name":"Division of Respiratory & Age-related Health, Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Universiteitssingel 40, 6229 ER \u00a0Maastricht, the Netherlands"},{"name":"Academic Sleep Centre CIRO , Hornerheide 1, 6085 NM Horn, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3803-8429","authenticated-orcid":false,"given":"Prashanthan","family":"Sanders","sequence":"additional","affiliation":[{"name":"Centre for Heart Rhythm Disorders, University of Adelaide and Royal Adelaide Hospital , 1 Port Road, SA 5000 Adelaide, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1073-5337","authenticated-orcid":false,"given":"Harry J G M","family":"Crijns","sequence":"additional","affiliation":[{"name":"University Maastricht, Cardiovascular Research Institute Maastricht (CARIM) , Universiteitssingel 50, 6229 ER Maastricht, the Netherlands"},{"name":"Department of Cardiology, Maastricht University Medical Centre , P. Debyelaan 25, 6229 HX Maastricht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4893-0824","authenticated-orcid":false,"given":"Dominik","family":"Linz","sequence":"additional","affiliation":[{"name":"Centre for Heart Rhythm Disorders, University of Adelaide and Royal Adelaide Hospital , 1 Port Road, SA 5000 Adelaide, Australia"},{"name":"University Maastricht, Cardiovascular Research Institute Maastricht (CARIM) , Universiteitssingel 50, 6229 ER Maastricht, the Netherlands"},{"name":"Department of Cardiology, Maastricht University Medical Centre , P. Debyelaan 25, 6229 HX Maastricht, the Netherlands"},{"name":"Department of Cardiology, Radboud University Medical Centre , Geert Grooteplein Zuid 10, 6525 GA Nijmegen, the Netherlands"},{"name":"Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 K\u00f8benhavn N, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,11,18]]},"reference":[{"key":"2022102512215009900_ehaa822-B1","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1161\/CIRCULATIONAHA.113.005119","article-title":"Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study","volume":"129","author":"Chugh","year":"2014","journal-title":"Circulation"},{"key":"2022102512215009900_ehaa822-B2","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S0140-6736(14)61774-8","article-title":"50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study","volume":"386","author":"Schnabel","year":"2015","journal-title":"Lancet"},{"key":"2022102512215009900_ehaa822-B3","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/S0140-6736(07)61377-4","article-title":"International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study","volume":"370","author":"Buist","year":"2007","journal-title":"Lancet"},{"key":"2022102512215009900_ehaa822-B4","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ahj.2016.08.011","article-title":"Impact of chronic obstructive pulmonary disease on prognosis in atrial fibrillation: a report from the EURObservational Research Programme Pilot Survey on Atrial Fibrillation (EORP-AF) general registry","volume":"181","author":"Proietti","year":"2016","journal-title":"Am Heart J"},{"key":"2022102512215009900_ehaa822-B5","doi-asserted-by":"crossref","first-page":"371","DOI":"10.2147\/COPD.S174443","article-title":"A prospective study of the clinical outcomes and prognosis associated with comorbid COPD in the atrial fibrillation population","volume":"14","author":"Rodr\u00edguez-Ma\u00f1ero","year":"2019","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"2022102512215009900_ehaa822-B6","first-page":"129","article-title":"Risk of new-onset atrial fibrillation in elderly patients with the overlap syndrome: a retrospective cohort study","volume":"10","author":"Ganga","year":"2013","journal-title":"J Geriatr Cardiol"},{"key":"2022102512215009900_ehaa822-B7","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.jacc.2009.11.040","article-title":"Progression from paroxysmal to persistent atrial \ufb01brillation clinical correlates and prognosis","volume":"55","author":"de Vos","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"2022102512215009900_ehaa822-B8","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1093\/europace\/eur406","article-title":"Clinical correlates of immediate success and outcome at 1-year follow-up of real-world cardioversion of atrial \ufb01brillation: the Euro Heart Survey","volume":"14","author":"Pisters","year":"2012","journal-title":"Europace"},{"key":"2022102512215009900_ehaa822-B9","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/j.1540-8167.2012.02448.x","article-title":"Impact of chronic obstructive pulmonary disease on procedural outcomes and quality of life in patients with atrial \ufb01brillation undergoing catheter ablation","volume":"24","author":"Gu","year":"2013","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2022102512215009900_ehaa822-B10","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ijcard.2017.02.017","article-title":"Chronic obstructive pulmonary disease predicts higher incidence and in hospital mortality for atrial fibrillation. An observational study using hospital discharge data in Spain (2004-2013","volume":"236","author":"M\u00e9ndez-Bail\u00f3n","year":"2017","journal-title":"Int J Cardiol"},{"key":"2022102512215009900_ehaa822-B11","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1136\/heartjnl-2017-312735","article-title":"Characteristics and outcomes of adults with chronic obstructive pulmonary disease and atrial fibrillation","volume":"104","author":"Durheim","year":"2018","journal-title":"Heart"},{"key":"2022102512215009900_ehaa822-B12","doi-asserted-by":"crossref","first-page":"2893","DOI":"10.1093\/eurheartj\/ehw210","article-title":"2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS","volume":"37","author":"Kirchhof","year":"2016","journal-title":"Eur Heart J"},{"key":"2022102512215009900_ehaa822-B13","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1093\/europace\/eux275","article-title":"2017\u2009HRS\/EHRA\/ECAS\/APHRS\/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: executive summary","volume":"20","author":"Calkins","year":"2018","journal-title":"Europace"},{"key":"2022102512215009900_ehaa822-B14","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1056\/NEJMra1900475","article-title":"Update on the pathogenesis of chronic obstructive pulmonary disease","volume":"381","author":"Agust","year":"2019","journal-title":"N Engl J Med"},{"key":"2022102512215009900_ehaa822-B15","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1183\/09031936.04.00113204","article-title":"Flow limitation and dynamic hyperinflation: key concepts in modern respiratory physiology","volume":"25","author":"Calverley","year":"2005","journal-title":"Eur Respir J"},{"key":"2022102512215009900_ehaa822-B16","doi-asserted-by":"crossref","first-page":"190065","DOI":"10.1183\/16000617.0065-2019","article-title":"Pulmonary hypertension and chronic lung disease: where are we headed?","volume":"28","author":"Elia","year":"2019","journal-title":"Eur Respir Rev"},{"key":"2022102512215009900_ehaa822-B17","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1001\/jamacardio.2018.0095","article-title":"Associations of obstructive sleep apnea with atrial fibrillation and continuous positive airway pressure treatment: a review","volume":"3","author":"Linz","year":"2018","journal-title":"JAMA Cardiol"},{"key":"2022102512215009900_ehaa822-B18","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.jacc.2019.06.066","article-title":"Right atrial mechanisms of atrial fibrillation in a rat model of right heart disease","volume":"74","author":"Hiram","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2022102512215009900_ehaa822-B19","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.trsl.2020.04.013","article-title":"Atrial arrhythmogenesis in a rabbit model of chronic obstructive pulmonary disease","volume":"223","author":"Chan","year":"2020","journal-title":"Transl Res"},{"key":"2022102512215009900_ehaa822-B20","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1378\/chest.106.5.1432","article-title":"Decreased heart rate variability in patients with chronic obstructive pulmonary disease","volume":"106","author":"Volterrani","year":"1994","journal-title":"Chest"},{"key":"2022102512215009900_ehaa822-B21","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1164\/ajrccm.164.4.2007085","article-title":"Marked sympathetic activation in patients with chronic respiratory failure","volume":"164","author":"Heindl","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"2022102512215009900_ehaa822-B22","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.ijcard.2018.11.091","article-title":"Atrial autonomic innervation: a target for interventional antiarrhythmic therapy?","volume":"287","author":"Linz","year":"2019","journal-title":"Int J Cardiol"},{"key":"2022102512215009900_ehaa822-B23","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1378\/chest.09-2810","article-title":"Decreasing cardiac chamber sizes and associated heart dysfunction in COPD: role of hyperinflation","volume":"138","author":"Watz","year":"2010","journal-title":"Chest"},{"key":"2022102512215009900_ehaa822-B24","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.jchf.2019.05.009","article-title":"Diagnostic and therapeutic gaps in patients with heart failure and chronic obstructive pulmonary disease","volume":"7","author":"Canepa","year":"2019","journal-title":"JACC Heart Fail"},{"key":"2022102512215009900_ehaa822-B25","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1093\/eurheartj\/ehy838","article-title":"Composition of nocturnal hypoxaemic burden and its prognostic value for cardiovascular mortality in older community-dwelling men","volume":"41","author":"Baumert","year":"2020","journal-title":"Eur Heart J"},{"key":"2022102512215009900_ehaa822-B26","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.chest.2018.12.021","article-title":"Prevalence of atrial fibrillation in hospital encounters with end-stage COPD on home oxygen: national trends in the United States","volume":"155","author":"Xiao","year":"2019","journal-title":"Chest"},{"key":"2022102512215009900_ehaa822-B27","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.ijcard.2018.09.056","article-title":"Chronic obstructive pulmonary disease and the development of atrial fibrillation","volume":"276","author":"Grymonprez","year":"2019","journal-title":"Int J Cardiol"},{"key":"2022102512215009900_ehaa822-B28","doi-asserted-by":"crossref","first-page":"e006322","DOI":"10.1161\/CIRCEP.118.006322","article-title":"Acute exacerbation of chronic obstructive pulmonary disease and subsequent risk of emergency department visits and hospitalizations for atrial fibrillation","volume":"11","author":"Hirayama","year":"2018","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2022102512215009900_ehaa822-B29","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.hrthm.2010.03.020","article-title":"Atrial electrophysiology is altered by acute hypercapnia but not hypoxemia: implications for promotion of atrial fibrillation in pulmonary disease and sleep apnea","volume":"7","author":"Stevenson","year":"2010","journal-title":"Heart Rhythm"},{"key":"2022102512215009900_ehaa822-B30","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.hrthm.2011.03.053","article-title":"Negative tracheal pressure during obstructive respiratory events promotes atrial fibrillation by vagal activation","volume":"8","author":"Linz","year":"2011","journal-title":"Heart Rhythm"},{"key":"2022102512215009900_ehaa822-B31","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1183\/09031936.00175714","article-title":"Obstructive respiratory events and premature atrial contractions after cardioversion","volume":"45","author":"Linz","year":"2015","journal-title":"Eur Respir J"},{"key":"2022102512215009900_ehaa822-B32","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.amjcard.2014.04.030","article-title":"Relation of chronic obstructive pulmonary disease to atrial and ventricular arrhythmias","volume":"114","author":"Konecny","year":"2014","journal-title":"Am J Cardiol"},{"key":"2022102512215009900_ehaa822-B33","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1183\/09031936.03.00051502","article-title":"Reduced lung function and risk of atrial fibrillation in the Copenhagen City Heart Study","volume":"21","author":"Buch","year":"2003","journal-title":"Eur Respir J"},{"key":"2022102512215009900_ehaa822-B34","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1161\/CIRCULATIONAHA.113.004050","article-title":"Airflow obstruction, lung function, and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study","volume":"129","author":"Li","year":"2014","journal-title":"Circulation"},{"key":"2022102512215009900_ehaa822-B35","doi-asserted-by":"crossref","first-page":"e006322","DOI":"10.1161\/CIRCEP.118.006322","article-title":"Acute exacerbation of chronic obstructive pulmonary disease and subsequent risk of emergency department visits and hospitalizations for atrial \ufb01brillation","volume":"11","author":"Hirayama","year":"2018","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2022102512215009900_ehaa822-B36","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.ijcard.2019.01.074","article-title":"The burden and impact of arrhythmia in chronic obstructive pulmonary disease: insights from the National Inpatient Sample","volume":"281","author":"Desai","year":"2019","journal-title":"Int J Cardiol"},{"key":"2022102512215009900_ehaa822-B37","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ijcard.2017.11.036","article-title":"Competitive interaction between chronic obstructive pulmonary disease and CHA2DS2-VASc score in predicting incident atrial fibrillation","volume":"255","author":"Perticone","year":"2018","journal-title":"Int J Cardiol"},{"key":"2022102512215009900_ehaa822-B38","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1093\/europace\/eut158","article-title":"Prevalence and electrophysiological characteristics of typical atrial flutter in patients with atrial fibrillation and chronic obstructive pulmonary disease","volume":"15","author":"Hayashi","year":"2013","journal-title":"Europace"},{"key":"2022102512215009900_ehaa822-B39","year":"2019"},{"key":"2022102512215009900_ehaa822-B40","doi-asserted-by":"crossref","first-page":"e008133","DOI":"10.1136\/bmjopen-2015-008133","article-title":"Diagnostic accuracy of screening tests for COPD: a systematic review and meta-analysis","volume":"5","author":"Haroon","year":"2015","journal-title":"BMJ Open"},{"key":"2022102512215009900_ehaa822-B41","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/s41533-018-0083-9","article-title":"Point of care microspirometry to facilitate the COPD diagnostic process in primary care: a clustered randomised trial","volume":"28","author":"Schermer","year":"2018","journal-title":"NPJ Prim Care Respir Med"},{"key":"2022102512215009900_ehaa822-B42","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1183\/16000617.0048-2016","article-title":"Exertional dyspnoea in chronic heart failure: the role of the lung and respiratory mechanical factors","volume":"25","author":"Dub\u00e9","year":"2016","journal-title":"Eur Respir Rev"},{"key":"2022102512215009900_ehaa822-B43","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","article-title":"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) Developed with the special contribution of the Heart Failure Association (HFA) of the ESC","volume":"37","author":"Ponikowski","year":"2016","journal-title":"Eur Heart J"},{"key":"2022102512215009900_ehaa822-B44","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1161\/CIRCHEARTFAILURE.114.001825","article-title":"Mechanisms of exercise intolerance in heart failure with preserved ejection fraction: the role of abnormal peripheral oxygen extraction","volume":"8","author":"Dhakal","year":"2015","journal-title":"Circ Heart Fail"},{"key":"2022102512215009900_ehaa822-B45","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/HCR.0000000000000423","article-title":"Exercise testing and exercise rehabilitation for patients with atrial fibrillation","volume":"39","author":"Keteyian","year":"2019","journal-title":"J Cardiopulm Rehabil Prev"},{"key":"2022102512215009900_ehaa822-B46","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1183\/16000617.0054-2016","article-title":"Exertional dyspnoea in COPD: the clinical utility of cardiopulmonary exercise testing","volume":"25","author":"O'Donnell","year":"2016","journal-title":"Eur Respir Rev"},{"key":"2022102512215009900_ehaa822-B47","doi-asserted-by":"crossref","first-page":"978","DOI":"10.5603\/KP.a2016.0044","article-title":"The role of HATCH score in predicting the success rate of sinus rhythm following electrical cardioversion of atrial fibrillation","volume":"74","author":"Emren","year":"2016","journal-title":"Kardiol Pol"},{"key":"2022102512215009900_ehaa822-B48","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1161\/CIRCEP.110.960435","article-title":"Catheter ablation of atrial fibrillation in patients with chronic lung disease","volume":"4","author":"Roh","year":"2011","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2022102512215009900_ehaa822-B49","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.009294","article-title":"Causes and predictors of readmission in patients with atrial fibrillation undergoing catheter ablation: a national population-based cohort study","volume":"7","author":"Arora","year":"2018","journal-title":"J Am Heart Assoc"},{"key":"2022102512215009900_ehaa822-B50","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s00392-014-0682-6","article-title":"Risk of atrial fibrillation, stroke, and death after radiofrequency catheter ablation of typical atrial flutter","volume":"103","author":"Seara","year":"2014","journal-title":"Clin Res Cardiol"},{"key":"2022102512215009900_ehaa822-B51","doi-asserted-by":"crossref","first-page":"e007775","DOI":"10.1161\/CIRCEP.119.007775","article-title":"Factors associated with large improvements in health-related quality of life in patients with atrial fibrillation: results from ORBIT-AF","volume":"13","author":"Steinberg","year":"2020","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2022102512215009900_ehaa822-B52","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1016\/j.hrthm.2015.04.008","article-title":"HATCH score in the prediction of new-onset atrial fibrillation after catheter ablation of typical atrial flutter","volume":"12","author":"Chen","year":"2015","journal-title":"Heart Rhythm"},{"key":"2022102512215009900_ehaa822-B53","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.amjcard.2011.04.024","article-title":"Population-level incidence and risk factors for pulmonary toxicity associated with amiodarone","volume":"108","author":"Jackevicius","year":"2011","journal-title":"Am J Cardiol"},{"key":"2022102512215009900_ehaa822-B54","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1513\/AnnalsATS.201708-626OC","article-title":"\u03b2-Blocker therapy and clinical outcomes in patients with moderate chronic obstructive pulmonary disease and heightened cardiovascular risk. An observational substudy of SUMMIT","volume":"15","author":"Dransfield","year":"2018","journal-title":"Ann Am Thorac Soc"},{"key":"2022102512215009900_ehaa822-B55","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1056\/NEJMoa1908142","article-title":"Metoprolol for the prevention of acute exacerbations of COPD","volume":"381","author":"Dransfield","year":"2019","journal-title":"N Engl J Med"},{"key":"2022102512215009900_ehaa822-B56","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/s13063-019-3907-1","article-title":"Beta-blockeRs tO patieNts with CHronIc Obstructive puLmonary diseasE (BRONCHIOLE)\u2014atudy protocol from a randomized controlled trial","volume":"21","author":"Sundh","year":"2020","journal-title":"Trials"},{"key":"2022102512215009900_ehaa822-B57","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1136\/heartjnl-2016-310897","article-title":"Cardiovascular outcomes with an inhaled beta2 agonist\/corticosteroid in patients with COPD at high cardiovascular risk","volume":"103","author":"Brook","year":"2017","journal-title":"Heart"},{"key":"2022102512215009900_ehaa822-B58","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1001\/jama.2019.4973","article-title":"Effect of aclidinium bromide on major cardiovascular events and exacerbations in high-risk patients with chronic obstructive pulmonary disease: the ASCENT-COPD randomized clinical trial","volume":"321","author":"Wise","year":"2019","journal-title":"JAMA"},{"key":"2022102512215009900_ehaa822-B59","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S2213-2600(15)00518-4","article-title":"Cardiac effects of current treatments of chronic obstructive pulmonary disease","volume":"4","author":"Lahousse","year":"2016","journal-title":"Lancet Respir Med"},{"key":"2022102512215009900_ehaa822-B60","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1378\/chest.11-1597","article-title":"Bronchodilator use and the risk of arrhythmia in COPD: part 2: reassessment in the larger Quebec cohort","volume":"142","author":"Wilchesky","year":"2012","journal-title":"Chest"},{"key":"2022102512215009900_ehaa822-B61","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1097\/01.ede.0000158743.90664.a7","article-title":"Respiratory medications and the risk of cardiac arrhythmias","volume":"16","author":"Huerta","year":"2005","journal-title":"Epidemiology"},{"key":"2022102512215009900_ehaa822-B62","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1001\/archinte.166.9.1016","article-title":"Corticosteroids and the risk of atrial fibrillation","volume":"166","author":"van der Hooft","year":"2006","journal-title":"Arch Intern Med"},{"key":"2022102512215009900_ehaa822-B63","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/S2213-2600(14)70153-5","article-title":"Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled clinical trial","volume":"2","author":"K\u00f6hnlein","year":"2014","journal-title":"Lancet Respir Med"},{"key":"2022102512215009900_ehaa822-B64","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1016\/j.jacc.2014.09.028","article-title":"Aggressive risk factor reduction study for atrial fibrillation and implications for the outcome of ablation: the ARREST-AF cohort study","volume":"64","author":"Pathak","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"2022102512215009900_ehaa822-B65","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1093\/europace\/euy117","article-title":"PREVEntion and regReSsive Effect of weight-loss and risk factor modification on Atrial Fibrillation: the REVERSE-AF study","volume":"20","author":"Middeldorp","year":"2018","journal-title":"Europace"},{"key":"2022102512215009900_ehaa822-B66","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1111\/resp.12966","article-title":"Home-based telerehabilitation via real-time videoconferencing improves endurance exercise capacity in patients with COPD: the randomized controlled TeleR Study","volume":"22","author":"Tsai","year":"2017","journal-title":"Respirology"},{"key":"2022102512215009900_ehaa822-B67","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.ijcard.2018.04.076","article-title":"Assessment and interpretation of sleep disordered breathing severity in cardiology: clinical implications and perspectives","volume":"271","author":"Linz","year":"2018","journal-title":"Int J Cardiol"}],"container-title":["European Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eurheartj\/article-pdf\/42\/5\/532\/46621182\/ehaa822.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurheartj\/article-pdf\/42\/5\/532\/46621182\/ehaa822.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T12:25:03Z","timestamp":1666700703000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurheartj\/article\/42\/5\/532\/5989803"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,18]]},"references-count":67,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2020,11,18]]},"published-print":{"date-parts":[[2021,2,1]]}},"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/ehaa822","relation":{},"ISSN":["0195-668X","1522-9645"],"issn-type":[{"value":"0195-668X","type":"print"},{"value":"1522-9645","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,2,1]]},"published":{"date-parts":[[2020,11,18]]}}}