{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T05:21:11Z","timestamp":1790572871264,"version":"4.1.0"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"42","license":[{"start":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T00:00:00Z","timestamp":1695686400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Chong Kun Dang Inc."}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background and Aims<\/jats:title>\n                  <jats:p>The authors investigated the impact of smoking and its cessation after percutaneous coronary intervention (PCI) on cardiovascular outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Using a nationwide database from the Korean National Health Insurance System, 74 471 patients undergoing PCI between 2009 and 2016 were classified as non-, ex-, or current smokers, depending on smoking status at the first health check-up within 1 year after PCI. The primary outcome was major adverse cardiovascular and cerebrovascular event (MACCE), a composite of all-cause death, myocardial infarction, coronary revascularization, and stroke.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>During 4.0 years of follow-up, current smokers had a 19.8% higher rate of MACCE than non-smokers [adjusted hazard ratio (aHR) 1.198; 95% confidence interval (CI) 1.137\u20131.263], and ex-smokers tended to have a comparable rate with that of non-smokers (aHR 1.036; 95% CI .992\u20131.081). For 31 887 patients with both pre- and post-PCI health check-up data, the effects of smoking cessation were analysed. Among quitters who stopped smoking after PCI, quitters with cumulative smoking exposure of &amp;lt;20 pack-years (PYs) tended to have a comparable rate of MACCE with that of persistent non-smokers. However, the rate in quitters with cumulative exposure of \u226520 PYs was comparable with that of persistent smokers [aHR (95% CI) for &amp;lt;10 PY, 1.182 (.971\u20131.438); 10\u201320 PYs 1.114 (.963\u20131.290); 20\u201330 PYs 1.206 (1.054\u20131.380); \u2265 30 PYs 1.227 (1.113\u20131.352); persistent smokers 1.223 (1.126\u20131.328), compared with persistent non-smokers, respectively, P for interaction &amp;lt;.001].<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Smoking is associated with a higher risk of adverse outcomes in patients undergoing PCI. Quitters after PCI with &amp;lt;20 PYs were associated with a risk comparable with that of non-smokers.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurheartj\/ehad616","type":"journal-article","created":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T21:37:33Z","timestamp":1695850653000},"page":"4461-4472","source":"Crossref","is-referenced-by-count":28,"title":["Smoking and cardiovascular outcomes after percutaneous coronary intervention: a Korean study"],"prefix":"10.1093","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0102-2810","authenticated-orcid":false,"given":"You-Jeong","family":"Ki","sequence":"first","affiliation":[{"name":"Cardiovascular Center, Uijeongbu Eulji Medical Center , Uijeongbu-si, Gyeonggi-do , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6096-1263","authenticated-orcid":false,"given":"Kyungdo","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Statistics and Actuarial Science, Soongsil University , Seoul , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0847-5329","authenticated-orcid":false,"given":"Hyo-Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Cardiovascular Center, Seoul National University Hospital , 101 Daehak-ro, Jongno-gu, Seoul 03080 , Republic of Korea"},{"name":"Department of Internal Medicine, College of Medicine, Seoul National University , 103 Daehak-ro, Jongno-gu, Seoul 03080 , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0016-0747","authenticated-orcid":false,"given":"Jung-Kyu","family":"Han","sequence":"additional","affiliation":[{"name":"Cardiovascular Center, Seoul National University Hospital , 101 Daehak-ro, Jongno-gu, Seoul 03080 , Republic of Korea"},{"name":"Department of Internal Medicine, College of Medicine, Seoul National University , 103 Daehak-ro, Jongno-gu, Seoul 03080 , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,9,26]]},"reference":[{"key":"2023110920445986800_ehad616-B1","author":"World Health Organization"},{"key":"2023110920445986800_ehad616-B2","author":"World Health Organization"},{"key":"2023110920445986800_ehad616-B3","doi-asserted-by":"crossref","first-page":"3259","DOI":"10.1093\/eurheartj\/eht352","article-title":"Managing tobacco use: the neglected cardiovascular disease risk factor","volume":"34","author":"Rigotti","year":"2013","journal-title":"Eur Heart J"},{"key":"2023110920445986800_ehad616-B4","doi-asserted-by":"crossref","first-page":"3243","DOI":"10.1161\/01.CIR.96.9.3243","article-title":"Cigarette smoking, cardiovascular disease, and stroke: a statement for healthcare professionals from the American Heart Association. 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