{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T18:08:26Z","timestamp":1793729306331,"version":"4.6.1"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"44","license":[{"start":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T00:00:00Z","timestamp":1699056000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HL125303"],"award-info":[{"award-number":["R01 HL125303"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["F32 HL154750-01A1"],"award-info":[{"award-number":["F32 HL154750-01A1"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Given limited evidence and lack of consensus on donor acceptance for heart transplant (HT), selection practices vary widely across HT centres in the USA. Similar variation likely exists on a broader scale\u2014across countries and HT systems\u2014but remains largely unexplored. This study characterized differences in heart donor populations and selection practices between the USA and Eurotransplant\u2014a consortium of eight European countries\u2014and their implications for system-wide outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Characteristics of adult reported heart donors and their utilization (the percentage of reported donors accepted for HT) were compared between Eurotransplant (n = 8714) and the USA (n = 60 882) from 2010 to 2020. Predictors of donor acceptance were identified using multivariable logistic regression. Additional analyses estimated the impact of achieving Eurotransplant-level utilization in the USA amongst donors of matched quality, using probability of acceptance as a marker of quality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eurotransplant reported donors were older with more cardiovascular risk factors but with higher utilization than in the USA (70% vs. 44%). Donor age, smoking history, and diabetes mellitus predicted non-acceptance in the USA and, by a lesser magnitude, in Eurotransplant; donor obesity and hypertension predicted non-acceptance in the USA only. Achieving Eurotransplant-level utilization amongst the top 30%\u201350% of donors (by quality) would produce an additional 506\u2013930 US HTs annually.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Eurotransplant countries exhibit more liberal donor heart acceptance practices than the USA. Adopting similar acceptance practices could help alleviate the scarcity of donor hearts and reduce waitlist morbidity in the USA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurheartj\/ehad684","type":"journal-article","created":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T09:36:31Z","timestamp":1697016991000},"page":"4665-4674","source":"Crossref","is-referenced-by-count":51,"title":["Disparities in donor heart acceptance between the USA and Europe: clinical implications"],"prefix":"10.1093","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7005-9938","authenticated-orcid":false,"given":"Brian","family":"Wayda","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Stanford University School of Medicine , Stanford, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8378-0633","authenticated-orcid":false,"given":"Philipp","family":"Angleitner","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical University of Vienna , Waehringer Guertel 18-20 , Vienna A-1090, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline M","family":"Smits","sequence":"additional","affiliation":[{"name":"Eurotransplant , Leiden , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arne","family":"van Kins","sequence":"additional","affiliation":[{"name":"Eurotransplant , Leiden , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Berchtold-Herz","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University of Freiburg , Freiburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"De Pauw","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ghent University Hospital , Ghent , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiel E","family":"Erasmus","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Groningen, University of Groningen , Groningen , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6956-9110","authenticated-orcid":false,"given":"Jan","family":"Gummert","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Heart and Diabetes Center NRW , Bad Oeynhausen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Istvan","family":"Hartyanszky","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University , Budapest , Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Knezevic","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Medical Center Ljubljana , Ljubljana , Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guenther","family":"Laufer","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical University of Vienna , Waehringer Guertel 18-20 , Vienna A-1090, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davor","family":"Milicic","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases, University Hospital Center Zagreb, University of Zagreb , Zagreb , Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8428-2302","authenticated-orcid":false,"given":"Filip","family":"Rega","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Katholieke Universiteit Leuven , Leuven , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P Christian","family":"Schulze","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, Jena University Hospital\u2014Friedrich Schiller University Jena , Am Klinikum 1 , Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"van Caeneghem","sequence":"additional","affiliation":[{"name":"Department of Cardiac Research, Universit\u00e9 Catholique de Louvain Clinique Saint-Luc , Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiran K","family":"Khush","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Stanford University School of Medicine , Stanford, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas O","family":"Zuckermann","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical University of Vienna , Waehringer Guertel 18-20 , Vienna A-1090, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,11,4]]},"reference":[{"key":"2023112102040114800_ehad684-B1","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.healun.2019.08.004","article-title":"The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-sixth adult heart transplantation report\u20142019; focus theme: donor and recipient size match","volume":"38","author":"Khush","year":"2019","journal-title":"J Heart Lung Transplant"},{"key":"2023112102040114800_ehad684-B2","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/ajt.16977","article-title":"OPTN\/SRTR 2020 annual data report: 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