{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T22:27:18Z","timestamp":1793831238976,"version":"4.6.1"},"reference-count":52,"publisher":"Oxford University Press (OUP)","issue":"48","license":[{"start":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T00:00:00Z","timestamp":1699228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>While endomyocardial biopsy (EMB) is recommended in adult patients with fulminant myocarditis, the clinical impact of its timing is still unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data were collected from 419 adult patients with clinically suspected fulminant myocarditis admitted to intensive care units across 36 tertiary centres in 15 countries worldwide. The diagnosis of myocarditis was histologically proven in 210 (50%) patients, either by EMB (n = 183, 44%) or by autopsy\/explanted heart examination (n = 27, 6%), and clinically suspected cardiac magnetic resonance imaging confirmed in 96 (23%) patients. The primary outcome of survival free of heart transplantation (HTx) or left ventricular assist device (LVAD) at 1 year was specifically compared between patients with early EMB (within 2 days after intensive care unit admission, n = 103) and delayed EMB (n = 80). A propensity score-weighted analysis was done to control for confounders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Median age on admission was 40 (29\u201352) years, and 322 (77%) patients received temporary mechanical circulatory support. A total of 273 (65%) patients survived without HTx\/LVAD. The primary outcome was significantly different between patients with early and delayed EMB (70% vs. 49%, P = .004). After propensity score weighting, the early EMB group still significantly differed from the delayed EMB group in terms of survival free of HTx\/LVAD (63% vs. 40%, P = .021). Moreover, early EMB was independently associated with a lower rate of death or HTx\/LVAD at 1 year (odds ratio of 0.44; 95% confidence interval: 0.22\u20130.86; P = .016).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Endomyocardial biopsy should be broadly and promptly used in patients admitted to the intensive care unit for clinically suspected fulminant myocarditis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurheartj\/ehad707","type":"journal-article","created":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T08:55:57Z","timestamp":1696668957000},"page":"5110-5124","source":"Crossref","is-referenced-by-count":75,"title":["Fulminant myocarditis proven by early biopsy and outcomes"],"prefix":"10.1093","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3063-1546","authenticated-orcid":false,"given":"Florent","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Cardiology, Foch Hospital , Suresnes , France"},{"name":"Medical Intensive Care Unit, Assistance Publique-H\u00f4pitaux de Paris, Piti\u00e9-Salp\u00eatri\u00e8re Hospital , Paris Cedex 13 , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Ammirati","sequence":"additional","affiliation":[{"name":"De Gasperis Cardio Center and Transplant Center, Niguarda Hospital , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7761-4228","authenticated-orcid":false,"given":"Maharajah","family":"Ponnaiah","sequence":"additional","affiliation":[{"name":"ICAN Intelligence and Omics, Institute of Cardiometabolism and Nutrition, Piti\u00e9-Salp\u00eatri\u00e8re Hospital , Paris , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0984-3472","authenticated-orcid":false,"given":"Santiago","family":"Montero","sequence":"additional","affiliation":[{"name":"Acute Cardiovascular Care Unit, Cardiology, Departament de Medicina, Hospital Germans Trias i Pujol, Universitat Aut\u00f2noma de Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Raimbault","sequence":"additional","affiliation":[{"name":"Medical Intensive Care Unit, Assistance Publique-H\u00f4pitaux de Paris, Piti\u00e9-Salp\u00eatri\u00e8re Hospital , Paris Cedex 13 , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darryl","family":"Abrams","sequence":"additional","affiliation":[{"name":"Columbia University College of Physicians and Surgeons\/NewYork-Presbyterian Hospital and Center for Acute Respiratory Failure, Columbia University Medical Center , New York, NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4308-506X","authenticated-orcid":false,"given":"Guillaume","family":"Lebreton","sequence":"additional","affiliation":[{"name":"Service de Chirurgie Cardiaque, Assistance Publique-H\u00f4pitaux de Paris, Sorbonne Universit\u00e9 , Paris Cedex 13 , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Pellegrino","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Alfred Hospital , Melbourne , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Ihle","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Alfred Hospital , Melbourne , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Bottiroli","sequence":"additional","affiliation":[{"name":"De Gasperis Cardio Center and Transplant Center, Niguarda Hospital , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Persichini","sequence":"additional","affiliation":[{"name":"Medical-Surgical Intensive Care Unit, F\u00e9lix Guyon Hospital , CHU de La R\u00e9union , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa Isabel","family":"Barrionuevo-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Intensive Cardiac Care Unit, Cardiology Department, Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, Bellvitge University Hospital , L'Hospitalet de Llobregat , Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Ariza-Sol\u00e9","sequence":"additional","affiliation":[{"name":"Intensive Cardiac Care Unit, Cardiology Department, Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, Bellvitge University Hospital , L'Hospitalet de Llobregat , Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline Yeung","family":"Ng","sequence":"additional","affiliation":[{"name":"Adult Intensive Care Unit, Queen Mary Hospital , Hong-Kong , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon Wai Ching","family":"Sin","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, The University of Hong Kong , Hong-Kong , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj","family":"Ayer","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, St Vincent Hospital , Sydney , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hergen","family":"Buscher","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, St Vincent Hospital , Sydney , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Slimane","family":"Belaid","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rangueil University Hospital , Toulouse , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9ment","family":"Delmas","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rangueil University Hospital , Toulouse , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Saint Jo\u00e3o Hospital , Porto , Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Roberto","family":"Roncon-Albuquerque","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Saint Jo\u00e3o Hospital , Porto , Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"L\u00f3pez-Sobrino","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Cl\u00ednic Barcelona , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen J H","family":"Bunge","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Adults, and Department of Cardiology, Erasmus Medical Center , Rotterdam , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Fisser","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, University Medical Centre Regensburg , Regensburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Franchineau","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine and Infectious Diseases, Assistance Publique-H\u00f4pitaux de Paris, Bichat-Claude Bernard Hospital, Sorbonne Universit\u00e9 , Paris Cedex 18 , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie","family":"McCanny","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust Hospital , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichiro","family":"Ohshimo","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University , Hiroshima , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0843-9512","authenticated-orcid":false,"given":"Alessandro","family":"Sionis","sequence":"additional","affiliation":[{"name":"Intensive Cardiac Care Unit, Department of Cardiology, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, Universitat Aut\u00f2noma de Barcelona , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Jos\u00e9","family":"Hern\u00e1ndez-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Advanced Heart Failure and Transplant Unit, Department of Cardiology, Hospital Universitario Puerta de Hierro , Madrid , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Barge-Caballero","sequence":"additional","affiliation":[{"name":"Cardiology Department, Complejo Hospitalario Universitario de A Coru\u00f1a (CHUAC), Instituto de Investigaci\u00f3n Biom\u00e9dica de A Coru\u00f1a (INIBIC), CIBERCV , A Coru\u00f1a , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Balik","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care, General University Hospital , Prague , Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique","family":"Muglia","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Erasme Hospital , Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunghoon","family":"Park","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Hallym University Sacred Heart Hospital , Anyang , South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk W","family":"Donker","sequence":"additional","affiliation":[{"name":"Intensive Care Center, University Medical Center Utrecht , Utrecht , The Netherlands"},{"name":"Cardiovascular and Respiratory Physiology, TechMed Center, University of Twente , Enschede , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Porral","sequence":"additional","affiliation":[{"name":"Intensive Care Department, Hospital Alvaro Cunqueiro , Vigo , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"A\u00efssaoui","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Cochin Hospital, Sorbonne Universit\u00e9, Assistance Publique-H\u00f4pitaux de Paris , Paris Cedex 5 , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armand","family":"Mekontso Dessap","sequence":"additional","affiliation":[{"name":"Medical Intensive Care Unit, Assistance Publique-H\u00f4pitaux de Paris, Mondor Hospital , Cr\u00e9teil , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Burgos","sequence":"additional","affiliation":[{"name":"Acute Cardiac Care Unit, Department of Cardiology, Hospital Marqu\u00e9s de Valdecilla , Santander , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Lesouhaitier","sequence":"additional","affiliation":[{"name":"Departement of Infectious Diseases and Intensive Care Unit, Pontchaillou Hospital , Rennes 35200 , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Fried","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Columbia University Irving Medical Center\/NewYork-Presbyterian Hospital , New York, NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Seung","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Korea University Anam Hospital , Seoul , South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Rosillo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Universitario La Paz, IDIPAZ , Madrid , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Scherrer","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care, CHU Rouen , Rouen F-76000 , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saad","family":"Nseir","sequence":"additional","affiliation":[{"name":"M\u00e9decine Intensive-R\u00e9animation, Inserm U1285, CNRS, UMR 8576-UGSF-Unit\u00e9 de Glycobiologie Structurale et Fonctionnelle, CHU de Lille, University Lille , Lille , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadrien","family":"Winszewski","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Jean-Minjoz Hospital , Besan\u00e7on , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Jorge-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Universitario de Canarias Nuestra Se\u00f1ora de Candelaria , Canary Islands , Tenerife, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Kimmoun","sequence":"additional","affiliation":[{"name":"CHRU de NANCY, Service de M\u00e9decine Intensive et R\u00e9animation, Inserm U1116, Universit\u00e9 de Lorraine , Nancy , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Diaz","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cl\u00ednica Las Condes , Las Condes , Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Combes","sequence":"additional","affiliation":[{"name":"Medical Intensive Care Unit, Assistance Publique-H\u00f4pitaux de Paris, Piti\u00e9-Salp\u00eatri\u00e8re Hospital , Paris Cedex 13 , France"},{"name":"Sorbonne Universit\u00e9, INSERM UMRS_1166-iCAN, Institute of Cardiometabolism and Nutrition , Paris , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2931-4412","authenticated-orcid":false,"given":"Matthieu","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Medical Intensive Care Unit, Assistance Publique-H\u00f4pitaux de Paris, Piti\u00e9-Salp\u00eatri\u00e8re Hospital , Paris Cedex 13 , France"},{"name":"Sorbonne Universit\u00e9, INSERM UMRS_1166-iCAN, Institute of Cardiometabolism and Nutrition , Paris , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the FULLMOON Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florent","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Kerneis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Montalescot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Philippe","family":"Collet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9ment","family":"Delmas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Slimane","family":"Belaid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoan","family":"Lavie-Badie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Biendel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Lesouhaitier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Marc","family":"Tadi\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Scherrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Barge-Caballero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Blanco-Canosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zulaika","family":"Grille-Cancela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Porral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Raposeiras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Rosillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esteban","family":"L\u00f3pez-de-S\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Sionis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00edctor Garc\u00eda","family":"Hernando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"L\u00f3pez-Sobrino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rut Andrea","family":"Riba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Sandoval","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Burgos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta Ruiz","family":"Lera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela Canteli","family":"Alvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina Castrillo","family":"Bustamante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia Royuela","family":"Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo Jorge-P\u00e9rez","family":"Mart\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Garc\u00eda-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta M","family":"Mart\u00edn-Cabeza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinis Reis","family":"Miranda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen J H","family":"Bunge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kadir","family":"Caliskan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Fried","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon Sin Wai","family":"Ching","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Seung","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jieon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong Ju","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichiro","family":"Ohshimo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuya","family":"Kikutani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuaki","family":"Shime","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,11,6]]},"reference":[{"key":"2024030118203250300_ehad707-B1","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1056\/NEJMra0800028","article-title":"Myocarditis","volume":"360","author":"Cooper","year":"2009","journal-title":"N Engl J Med"},{"key":"2024030118203250300_ehad707-B2","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/S0140-6736(11)60648-X","article-title":"Myocarditis","volume":"379","author":"Sagar","year":"2012","journal-title":"Lancet"},{"key":"2024030118203250300_ehad707-B3","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1038\/nrcardio.2015.108","article-title":"Viral myocarditis\u2014diagnosis, treatment options, and current controversies","volume":"12","author":"Pollack","year":"2015","journal-title":"Nat Rev Cardiol."},{"key":"2024030118203250300_ehad707-B4","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/s41569-020-00435-x","article-title":"Myocarditis and inflammatory cardiomyopathy: current evidence and future directions","volume":"18","author":"Tsch\u00f6pe","year":"2021","journal-title":"Nat Rev Cardiol"},{"key":"2024030118203250300_ehad707-B5","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1093\/eurheartj\/eht210","article-title":"Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology working group on myocardial and pericardial diseases","volume":"34","author":"Caforio","year":"2013","journal-title":"Eur Heart J"},{"key":"2024030118203250300_ehad707-B6","doi-asserted-by":"crossref","first-page":"e69","DOI":"10.1161\/CIR.0000000000000745","article-title":"Recognition and initial management of fulminant myocarditis: a scientific statement from the American Heart Association","volume":"141","author":"Kociol","year":"2020","journal-title":"Circulation"},{"key":"2024030118203250300_ehad707-B7","doi-asserted-by":"crossref","first-page":"e007405","DOI":"10.1161\/CIRCHEARTFAILURE.120.007405","article-title":"Management of acute myocarditis and chronic inflammatory cardiomyopathy: an expert consensus document","volume":"13","author":"Ammirati","year":"2020","journal-title":"Circ Heart Fail."},{"key":"2024030118203250300_ehad707-B8","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1097\/CCM.0000000000000920","article-title":"Extracorporeal membrane oxygenation for the support of adults with acute myocarditis","volume":"43","author":"Diddle","year":"2015","journal-title":"Crit Care Med"},{"key":"2024030118203250300_ehad707-B9","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1253\/circj.CJ-17-0549","article-title":"Early prediction model for successful bridge to recovery in patients with fulminant myocarditis supported with percutaneous venoarterial extracorporeal membrane oxygenation\u2014insights from the CHANGE PUMP study","volume":"82","author":"Sawamura","year":"2018","journal-title":"Circ J"},{"key":"2024030118203250300_ehad707-B10","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.jacc.2019.04.063","article-title":"Fulminant versus acute nonfulminant myocarditis in patients with left ventricular systolic dysfunction","volume":"74","author":"Ammirati","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2024030118203250300_ehad707-B11","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1002\/ejhf.2190","article-title":"Heart failure association of the ESC, heart failure society of America and Japanese Heart Failure Society position statement on endomyocardial biopsy","volume":"23","author":"Seferovi","year":"2021","journal-title":"Eur J Heart Fail"},{"key":"2024030118203250300_ehad707-B12","doi-asserted-by":"crossref","first-page":"3076","DOI":"10.1093\/eurheartj\/ehm456","article-title":"The role of endomyocardial biopsy in the management of cardiovascular disease: a scientific statement from the American Heart Association, the American College of Cardiology, and the European Society of Cardiology endorsed by the Heart Failure Society of America and the Heart Failure Association of the European Society of Cardiology","volume":"28","author":"Cooper","year":"2007","journal-title":"Eur Heart J"},{"key":"2024030118203250300_ehad707-B13","doi-asserted-by":"crossref","first-page":"e023719","DOI":"10.1161\/JAHA.121.023719","article-title":"Differences in prognosis and cardiac function according to required percutaneous mechanical circulatory support and histological findings in patients with fulminant myocarditis: insights from the CHANGE PUMP 2 study","volume":"11","author":"Kondo","year":"2022","journal-title":"J Am Heart Assoc"},{"key":"2024030118203250300_ehad707-B14","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.athoracsur.2015.08.014","article-title":"Venoarterial extracorporeal membrane oxygenation for acute fulminant myocarditis in adult patients: a 5-year multi-institutional experience","volume":"101","author":"Lorusso","year":"2016","journal-title":"Ann Thorac Surg"},{"key":"2024030118203250300_ehad707-B15","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1253\/circj.66.133","article-title":"National survey of fulminant myocarditis in Japan: therapeutic guidelines and long-term prognosis of using percutaneous cardiopulmonary support for fulminant myocarditis (special report from a scientific committee)","volume":"66","author":"Aoyama","year":"2002","journal-title":"Circ J"},{"key":"2024030118203250300_ehad707-B16","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1097\/CCM.0b013e31820ead45","article-title":"Outcomes, long-term quality of life, and psychologic assessment of fulminant myocarditis patients rescued by mechanical circulatory support","volume":"39","author":"Mirabel","year":"2011","journal-title":"Crit Care Med"},{"key":"2024030118203250300_ehad707-B17","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1007\/s00380-011-0211-8","article-title":"Long-term follow-up on cardiac function following fulminant myocarditis requiring percutaneous extracorporeal cardiopulmonary support","volume":"28","author":"Ishida","year":"2013","journal-title":"Heart Vessels"},{"key":"2024030118203250300_ehad707-B18","first-page":"3","article-title":"Myocarditis. A histopathologic definition and classification","volume":"1","author":"Aretz","year":"1987","journal-title":"Am J Cardiovasc Pathol"},{"key":"2024030118203250300_ehad707-B19","doi-asserted-by":"crossref","first-page":"3158","DOI":"10.1016\/j.jacc.2018.09.072","article-title":"Cardiovascular magnetic resonance in nonischemic myocardial inflammation","volume":"72","author":"Ferreira","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"2024030118203250300_ehad707-B20","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1007\/BF01709751","article-title":"The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction\/failure","volume":"22","author":"Vincent","year":"1996","journal-title":"Intensive Care Med"},{"key":"2024030118203250300_ehad707-B21","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1001\/jama.1993.03510240069035","article-title":"A new simplified acute physiology score (SAPS II) based on a European\/North American multicenter study","volume":"270","author":"Le Gall","year":"1993","journal-title":"JAMA"},{"key":"2024030118203250300_ehad707-B22","doi-asserted-by":"crossref","first-page":"2246","DOI":"10.1093\/eurheartj\/ehv194","article-title":"Predicting survival after ECMO for refractory cardiogenic shock: the survival after veno-arterial-ECMO (SAVE)-score","volume":"36","author":"Schmidt","year":"2015","journal-title":"Eur Heart J"},{"key":"2024030118203250300_ehad707-B23","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"370","author":"von Elm","year":"2007","journal-title":"Lancet"},{"key":"2024030118203250300_ehad707-B24","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1161\/CIRCULATIONAHA.118.035319","article-title":"Clinical presentation and outcome in a contemporary cohort of patients with acute myocarditis: multicenter lombardy registry","volume":"138","author":"Ammirati","year":"2018","journal-title":"Circulation"},{"key":"2024030118203250300_ehad707-B25","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1093\/eurjhf\/hfq229","article-title":"Prognostic electrocardiographic parameters in patients with suspected myocarditis","volume":"13","author":"Ukena","year":"2011","journal-title":"Eur J Heart Fail"},{"key":"2024030118203250300_ehad707-B26","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1007\/s00380-017-0960-0","article-title":"Factors and values at admission that predict a fulminant course of acute myocarditis: data from Tokyo CCU network database","volume":"32","author":"Inaba","year":"2017","journal-title":"Heart Vessels"},{"key":"2024030118203250300_ehad707-B27","first-page":"682","article-title":"Extracorporeal membranous oxygenation support for acute fulminant myocarditis: analysis of a single center\u2019s experience","volume":"40","author":"Hsu","year":"2011","journal-title":"Eur J Cardio-Thorac Surg"},{"key":"2024030118203250300_ehad707-B28","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1093\/eurheartj\/ehi411","article-title":"Favourable clinical outcome in patients with cardiogenic shock due to fulminant myocarditis supported by percutaneous extracorporeal membrane oxygenation","volume":"26","author":"Asaumi","year":"2005","journal-title":"Eur Heart J."},{"key":"2024030118203250300_ehad707-B29","doi-asserted-by":"crossref","first-page":"b2393","DOI":"10.1136\/bmj.b2393","article-title":"Multiple imputation for missing data in epidemiological and clinical research: potential and pitfalls","volume":"338","author":"Sterne","year":"2009","journal-title":"BMJ"},{"key":"2024030118203250300_ehad707-B30","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1161\/CIRCULATIONAHA.117.026386","article-title":"Survival and left ventricular function changes in fulminant versus nonfulminant acute myocarditis","volume":"136","author":"Ammirati","year":"2017","journal-title":"Circulation"},{"key":"2024030118203250300_ehad707-B31","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1161\/CIRCULATIONAHA.121.058869","article-title":"Features and outcomes of histologically proven myocarditis with fulminant presentation","volume":"146","author":"Kanaoka","year":"2022","journal-title":"Circulation"},{"key":"2024030118203250300_ehad707-B32","doi-asserted-by":"crossref","first-page":"838564","DOI":"10.3389\/fmed.2022.838564","article-title":"Immunomodulating therapies in acute myocarditis and recurrent\/acute pericarditis","volume":"9","author":"Ammirati","year":"2022","journal-title":"Front Med"},{"key":"2024030118203250300_ehad707-B33","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1016\/j.jacc.2017.09.023","article-title":"Eosinophilic myocarditis: characteristics, treatment, and outcomes","volume":"70","author":"Brambatti","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2024030118203250300_ehad707-B34","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1136\/heartjnl-2020-317202","article-title":"Hypereosinophilic syndrome: considerations for the cardiologist","volume":"108","author":"Bondue","year":"2022","journal-title":"Heart"},{"key":"2024030118203250300_ehad707-B35","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/j.jacc.2020.11.074","article-title":"Management of patients with giant cell myocarditis: JACC review topic of the week","volume":"77","author":"Bang","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"2024030118203250300_ehad707-B36","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1001\/jamacardio.2021.2241","article-title":"Clinical strategy for the diagnosis and treatment of immune checkpoint inhibitor-associated myocarditis: a narrative review","volume":"6","author":"Lehmann","year":"2021","journal-title":"JAMA Cardiol"},{"key":"2024030118203250300_ehad707-B37","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1056\/NEJM199508033330501","article-title":"A clinical trial of immunosuppressive therapy for myocarditis. The myocarditis treatment trial investigators","volume":"333","author":"Mason","year":"1995","journal-title":"N Engl J Med"},{"key":"2024030118203250300_ehad707-B38","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1161\/01.CIR.104.1.39","article-title":"Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results","volume":"104","author":"Wojnicz","year":"2001","journal-title":"Circulation"},{"key":"2024030118203250300_ehad707-B39","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1093\/eurheartj\/ehp249","article-title":"Randomized study on the efficacy of immunosuppressive therapy in patients with virus-negative inflammatory cardiomyopathy: the TIMIC study","volume":"30","author":"Frustaci","year":"2009","journal-title":"Eur Heart J"},{"key":"2024030118203250300_ehad707-B40","doi-asserted-by":"crossref","first-page":"3463","DOI":"10.1093\/eurheartj\/ehac348","article-title":"Immunosuppressive therapy in virus-negative inflammatory cardiomyopathy: 20-year follow-up of the TIMIC trial","volume":"43","author":"Chimenti","year":"2022","journal-title":"Eur Heart J"},{"key":"2024030118203250300_ehad707-B41","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.ijcard.2017.10.053","article-title":"Fulminant giant-cell myocarditis on mechanical circulatory support: management and outcomes of a French multicentre cohort","volume":"253","author":"Montero","year":"2018","journal-title":"Int J Cardiol"},{"key":"2024030118203250300_ehad707-B42","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1056\/NEJM199706263362603","article-title":"Idiopathic giant-cell myocarditis\u2013natural history and treatment. Multicenter giant cell myocarditis study group investigators","volume":"336","author":"Cooper","year":"1997","journal-title":"N Engl J Med"},{"key":"2024030118203250300_ehad707-B43","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1161\/CIRCHEARTFAILURE.112.969261","article-title":"Diagnosis, treatment, and outcome of giant-cell myocarditis in the era of combined immunosuppression","volume":"6","author":"Kandolin","year":"2013","journal-title":"Circ Heart Fail"},{"key":"2024030118203250300_ehad707-B44","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1002\/ejhf.606","article-title":"Long-term outcome and its predictors in giant cell myocarditis","volume":"18","author":"Ekstr\u00f6m","year":"2016","journal-title":"Eur J Heart Fail"},{"key":"2024030118203250300_ehad707-B45","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.amjcard.2017.10.021","article-title":"Comparison of utilization trends, indications, and complications of endomyocardial biopsy in native versus donor hearts (from the nationwide inpatient sample 2002 to 2014)","volume":"121","author":"Singh","year":"2018","journal-title":"Am J Cardiol"},{"key":"2024030118203250300_ehad707-B46","doi-asserted-by":"crossref","first-page":"e008387","DOI":"10.1161\/CIRCHEARTFAILURE.121.008387","article-title":"Safety of endomyocardial biopsy in new-onset acute heart failure requiring veno-arterial extracorporeal membrane oxygenation","volume":"14","author":"van der Boon","year":"2021","journal-title":"Circ Heart Fail"},{"key":"2024030118203250300_ehad707-B47","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/s11886-022-01680-x","article-title":"State-of-the-art of endomyocardial biopsy on acute myocarditis and chronic inflammatory cardiomyopathy","volume":"24","author":"Ammirati","year":"2022","journal-title":"Curr Cardiol Rep"},{"key":"2024030118203250300_ehad707-B48","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1002\/ejhf.2496","article-title":"Predictors of relapse, death or heart transplantation in myocarditis before the introduction of immunosuppression: negative prognostic impact of female gender, fulminant onset, lower ejection fraction and serum autoantibodies","volume":"24","author":"Baritussio","year":"2022","journal-title":"Eur J Heart Fail"},{"key":"2024030118203250300_ehad707-B49","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1164\/rccm.201409-1634OC","article-title":"Association of hospital-level volume of extracorporeal membrane oxygenation cases and mortality. Analysis of the extracorporeal life support organization registry","volume":"191","author":"Barbaro","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"key":"2024030118203250300_ehad707-B50","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.chest.2020.08.2099","article-title":"Coronavirus disease 2019 acute myocarditis and multisystem inflammatory syndrome in adult intensive and cardiac care units","volume":"159","author":"H\u00e9kimian","year":"2021","journal-title":"Chest"},{"key":"2024030118203250300_ehad707-B51","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1016\/j.jacc.2018.02.037","article-title":"Myocarditis in patients treated with immune checkpoint inhibitors","volume":"71","author":"Mahmood","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"2024030118203250300_ehad707-B52","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1161\/CIRCULATIONAHA.121.056817","article-title":"Prevalence, characteristics, and outcomes of COVID-19-associated acute myocarditis","volume":"145","author":"Ammirati","year":"2022","journal-title":"Circulation"}],"container-title":["European Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eurheartj\/article-pdf\/44\/48\/5110\/56813950\/ehad707.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurheartj\/article-pdf\/44\/48\/5110\/56813950\/ehad707.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T13:20:51Z","timestamp":1709299251000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurheartj\/article\/44\/48\/5110\/7370226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,6]]},"references-count":52,"journal-issue":{"issue":"48","published-online":{"date-parts":[[2023,11,6]]},"published-print":{"date-parts":[[2023,12,21]]}},"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/ehad707","relation":{},"ISSN":["0195-668X","1522-9645"],"issn-type":[{"value":"0195-668X","type":"print"},{"value":"1522-9645","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,12,21]]},"published":{"date-parts":[[2023,11,6]]}}}