{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T02:40:38Z","timestamp":1790217638209,"version":"4.1.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T00:00:00Z","timestamp":1704758400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Leonie-Wild Foundation"},{"name":"Leyla Erkan Family Fund"},{"DOI":"10.13039\/501100006688","name":"ARVD","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006688","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hugh Calkins"},{"name":"Bernstein Cardiac Arrhythmia Center"},{"name":"Chiaramonte Private Foundation"},{"name":"Robin Shah ARVD Fund"},{"name":"Bogle Foundation"},{"name":"Campanella Family"},{"name":"Harrison Family"},{"DOI":"10.13039\/501100019817","name":"Peter French Memorial Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019817","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Wilmerding Endowments"},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["T32HL007227"],"award-info":[{"award-number":["T32HL007227"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["L30HL165535"],"award-info":[{"award-number":["L30HL165535"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Philippa and Marvin Carsley Cardiology Research Chair"},{"DOI":"10.13039\/501100012651","name":"Montreal Heart Institute Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012651","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000156","name":"FRQS","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000156","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005416","name":"Norwegian Research Council","doi-asserted-by":"publisher","award":["309762"],"award-info":[{"award-number":["309762"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005416","name":"Norwegian Research Council","doi-asserted-by":"publisher","award":["288438"],"award-info":[{"award-number":["288438"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005416","name":"Norwegian Research Council","doi-asserted-by":"publisher","award":["298736"],"award-info":[{"award-number":["298736"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001826","name":"ZonMW","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Dutch Heart Association"},{"name":"Netherlands Cardiovascular Research Initiative"},{"DOI":"10.13039\/501100002996","name":"Dutch Heart Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002996","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Netherlands Arrhythmogenic Cardiomyopathy"},{"DOI":"10.13039\/100009183","name":"ACM","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009183","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014470","name":"Netherlands Heart Institute","doi-asserted-by":"publisher","award":["project 06901"],"award-info":[{"award-number":["project 06901"]}],"id":[{"id":"10.13039\/501100014470","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Zurich ARVC Program"},{"DOI":"10.13039\/501100011561","name":"Georg and Bertha Schwyzer-Winiker Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011561","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007252","name":"Baugarten Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007252","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Swiss National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004362","name":"Swiss Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004362","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Daniel Bravo Foundation and Spanish Society of Cardiology"},{"name":"Swedish Heart Lung and ALF foundations"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,2,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background and Aims<\/jats:title>\n                  <jats:p>Implantable cardioverter-defibrillators (ICDs) are critical for preventing sudden cardiac death (SCD) in arrhythmogenic right ventricular cardiomyopathy (ARVC). This study aims to identify cross-continental differences in utilization of primary prevention ICDs and survival free from sustained ventricular arrhythmia (VA) in ARVC.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This was a retrospective analysis of ARVC patients without prior VA enrolled in clinical registries from 11 countries throughout Europe and North America. Patients were classified according to whether they received treatment in North America or Europe and were further stratified by baseline predicted VA risk into low- (&amp;lt;10%\/5 years), intermediate- (10%\u201325%\/5 years), and high-risk (&amp;gt;25%\/5 years) groups. Differences in ICD implantation and survival free from sustained VA events (including appropriate ICD therapy) were assessed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>One thousand ninety-eight patients were followed for a median of 5.1 years; 554 (50.5%) received a primary prevention ICD, and 286 (26.0%) experienced a first VA event. After adjusting for baseline risk factors, North Americans were more than three times as likely to receive ICDs {hazard ratio (HR) 3.1 [95% confidence interval (CI) 2.5, 3.8]} but had only mildly increased risk for incident sustained VA [HR 1.4 (95% CI 1.1, 1.8)]. North Americans without ICDs were at higher risk for incident sustained VA [HR 2.1 (95% CI 1.3, 3.4)] than Europeans.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>North American ARVC patients were substantially more likely than Europeans to receive primary prevention ICDs across all arrhythmic risk strata. A lower rate of ICD implantation in Europe was not associated with a higher rate of VA events in those without ICDs.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurheartj\/ehad799","type":"journal-article","created":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T00:01:25Z","timestamp":1704844885000},"page":"538-548","source":"Crossref","is-referenced-by-count":23,"title":["Implantable cardioverter defibrillator use in arrhythmogenic right ventricular cardiomyopathy in North America and Europe"],"prefix":"10.1093","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5589-1216","authenticated-orcid":false,"given":"Richard T","family":"Carrick","sequence":"first","affiliation":[{"name":"Heart and Vascular Institute, Johns Hopkins University , Baltimore, MD , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4717-2892","authenticated-orcid":false,"given":"Corrado","family":"De Marco","sequence":"additional","affiliation":[{"name":"Cardiovascular Genetics Centre, Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al , 5000 rue B\u00e9langer , Montr\u00e9al, Qu\u00e9bec H1T 1C8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3432-070X","authenticated-orcid":false,"given":"Alessio","family":"Gasperetti","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute, Johns Hopkins University , Baltimore, MD , USA"},{"name":"Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University , Utrecht , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7847-4607","authenticated-orcid":false,"given":"Laurens P","family":"Bosman","sequence":"additional","affiliation":[{"name":"Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University , Utrecht , The Netherlands"},{"name":"Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6961-2131","authenticated-orcid":false,"given":"Jean-Baptiste","family":"Gourraud","sequence":"additional","affiliation":[{"name":"Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart)"},{"name":"Department of Cardiology, Centre Hospitalier Universitaire Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2181-8245","authenticated-orcid":false,"given":"Alessandro","family":"Trancuccio","sequence":"additional","affiliation":[{"name":"Molecular Cardiology, Istituti Clinici Scientifici Maugeri (IRCCS) , Pavia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0208-2172","authenticated-orcid":false,"given":"Andrea","family":"Mazzanti","sequence":"additional","affiliation":[{"name":"Molecular Cardiology, Istituti Clinici Scientifici Maugeri (IRCCS) , Pavia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7870-8584","authenticated-orcid":false,"given":"Brittney","family":"Murray","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute, Johns Hopkins University , Baltimore, MD , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Pendleton","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute, Johns Hopkins University , Baltimore, MD , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crystal","family":"Tichnell","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute, Johns Hopkins University , Baltimore, MD , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harikrishna","family":"Tandri","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute, Johns Hopkins University , Baltimore, MD , USA"},{"name":"Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7034-1017","authenticated-orcid":false,"given":"Katja","family":"Zeppenfeld","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Center , Leiden , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur A M","family":"Wilde","sequence":"additional","affiliation":[{"name":"Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart)"},{"name":"Amsterdam UMC, Heart Center Department of Cardiology, Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, University of Amsterdam , Amsterdam , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9469-7109","authenticated-orcid":false,"given":"Brianna","family":"Davies","sequence":"additional","affiliation":[{"name":"Center for Cardiac Innovation, Division of Cardiology, University of British Columbia , Vancouver, British Columbia , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colette","family":"Seifer","sequence":"additional","affiliation":[{"name":"St.Boniface Hospital, University of Manitoba , Winnipeg, Manitoba , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason D","family":"Roberts","sequence":"additional","affiliation":[{"name":"Hamilton Health Sciences, Population Health Research Institute, McMaster University , Hamilton, Ontario , Canada"},{"name":"Section of Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, Western University , London, Ontario , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeff S","family":"Healey","sequence":"additional","affiliation":[{"name":"Hamilton Health Sciences, Population Health Research Institute, McMaster University , Hamilton, Ontario , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciorsti","family":"MacIntyre","sequence":"additional","affiliation":[{"name":"Queen Elizabeth II Health Sciences Centre, Dalhousie University , Halifax, Nova Scotia , Canada"},{"name":"Department of Medicine, Mayo Clinic , Rochester, Minnesota , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5324-6993","authenticated-orcid":false,"given":"Wael","family":"Alqarawi","sequence":"additional","affiliation":[{"name":"Department of Cardiac Sciences, College of Medicine, King Saudi University , Riyadh , Saudi Arabia"},{"name":"Division of Cardiology, University of Ottawa Heart Institute, University of Ottawa , Ottawa , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafik","family":"Tadros","sequence":"additional","affiliation":[{"name":"Cardiovascular Genetics Centre, Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al , 5000 rue B\u00e9langer , Montr\u00e9al, Qu\u00e9bec H1T 1C8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J","family":"Cutler","sequence":"additional","affiliation":[{"name":"Intermountain Medical Center, Intermountain Medical Center Heart Institute , Murray, UT , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mattia","family":"Targetti","sequence":"additional","affiliation":[{"name":"Cardiomyopathy Unit, Careggi Hospital and Meyer Children\u2019s Hospital IRCCS , Florence , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Cal\u00f2","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Policlinico Casilino , Rome , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Vitali","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Sant\u2019Anna University Hospital, University of Ferrara , Ferrara , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5285-7140","authenticated-orcid":false,"given":"Matteo","family":"Bertini","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Sant\u2019Anna University Hospital, University of Ferrara , Ferrara , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1924-6548","authenticated-orcid":false,"given":"Paolo","family":"Compagnucci","sequence":"additional","affiliation":[{"name":"Cardiology and Arrhythmology Clinic, University Hospital Ospedali Riuniti , Ancona , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michela","family":"Casella","sequence":"additional","affiliation":[{"name":"Cardiology and Arrhythmology Clinic, University Hospital Ospedali Riuniti , Ancona , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Dello Russo","sequence":"additional","affiliation":[{"name":"Cardiology and Arrhythmology Clinic, University Hospital Ospedali Riuniti , Ancona , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5447-5595","authenticated-orcid":false,"given":"Chiara","family":"Cappelletto","sequence":"additional","affiliation":[{"name":"Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart)"},{"name":"Division of Cardiology, Cardiothoracovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina and University of Trieste , Trieste , Italy"},{"name":"Division of Cardiology, Department of Medicine, Karolinska Institutet, Solna , Stockholm , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"De Luca","sequence":"additional","affiliation":[{"name":"Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart)"},{"name":"Division of Cardiology, Cardiothoracovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina and University of Trieste , Trieste , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4538-6811","authenticated-orcid":false,"given":"Davide","family":"Stolfo","sequence":"additional","affiliation":[{"name":"Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart)"},{"name":"Division of Cardiology, Cardiothoracovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina and University of Trieste , Trieste , Italy"},{"name":"Division of Cardiology, Department of Medicine, Karolinska Institutet, Solna , Stockholm , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4748-0158","authenticated-orcid":false,"given":"Firat","family":"Duru","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Heart Center Zurich , Zurich , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik K","family":"Jensen","sequence":"additional","affiliation":[{"name":"Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart)"},{"name":"Department of Cardiology, Aarhus University Hospital , Aarhus N , Denmark"},{"name":"Department of Clinical Medicine, Health, Aarhus University , Aarhus N , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anneli","family":"Svensson","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Link\u00f6ping University Hospital , Link\u00f6ping , Sweden"},{"name":"Department of Health, Medicine and Caring Sciences, Link\u00f6ping University , Link\u00f6ping , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia","family":"Dahlberg","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Sahlgrenska University Hospital , Gothenburg , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina E","family":"Hasselberg","sequence":"additional","affiliation":[{"name":"ProCardio Center for Innovation, Department of Cardiology, Oslo University Hospital, Rikshospitalet, University of Oslo , Oslo , Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8322-8112","authenticated-orcid":false,"given":"Andrea","family":"Di Marco","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Department ofCardiology, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat , Barcelona , Spain"},{"name":"BioHeartCardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paloma","family":"Jord\u00e0","sequence":"additional","affiliation":[{"name":"Cardiovascular Genetics Centre, Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al , 5000 rue B\u00e9langer , Montr\u00e9al, Qu\u00e9bec H1T 1C8, Canada"},{"name":"Arrhythmia Section, Department of Cardiology, Hospital Cl\u00ednic, Universitat de Barcelona , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0424-6393","authenticated-orcid":false,"given":"Elena","family":"Arbelo","sequence":"additional","affiliation":[{"name":"Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart)"},{"name":"Arrhythmia Section, Department of Cardiology, Hospital Cl\u00ednic, Universitat de Barcelona , Barcelona , Spain"},{"name":"Institut d'Investigaci\u00f3 August Pi i Sunyer (IDIBAPS), Barcelona, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoraida","family":"Moreno Weidmann","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Department of Cardiology, Hospital Universitari Sant Pau , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Borowiec","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Diseases, Cardinal Wyszynski National Institute of Cardiology , Warsaw , Poland"},{"name":"Outpatient Department of Genetic Arrhythmias, Cardinal Wyszynski National Institute of Cardiology , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3742-9674","authenticated-orcid":false,"given":"Antoine","family":"Delini\u00e8re","sequence":"additional","affiliation":[{"name":"Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart)"},{"name":"Department of Cardiology, National Reference Center for Inherited Arrhythmias of Lyon, Louis Pradel Cardiovascular Hospital, Hospices Civils de Lyon , Lyon , France"},{"name":"University of Lyon, Claude Bernard Lyon 1 University, MeLiS, CNRS UMR 5284, INSERM U1314, Institut NeuroMyoG\u00e8ne, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"El\u017cbieta K","family":"Biernacka","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Diseases, Cardinal Wyszynski National Institute of Cardiology , Warsaw , Poland"},{"name":"Outpatient Department of Genetic Arrhythmias, Cardinal Wyszynski National Institute of Cardiology , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J Peter","family":"van Tintelen","sequence":"additional","affiliation":[{"name":"Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart)"},{"name":"Department of Genetics, University Medical Center Utrecht, Utrecht University , Utrecht , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pyotr G","family":"Platonov","sequence":"additional","affiliation":[{"name":"Department of Cardiology, 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Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moniek","family":"Cox","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Medical Center Groningen , Groningen , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Tondo","sequence":"additional","affiliation":[{"name":"Department of Clinical Electrophysiology and Cardiac Pacing, Centro Cardiologico Monzino, IRCCS, University of Milan , Milan , Italy"},{"name":"Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1022-3131","authenticated-orcid":false,"given":"Marco","family":"Merlo","sequence":"additional","affiliation":[{"name":"Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart)"},{"name":"Division of Cardiology, Cardiothoracovascular 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