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Using data from women enrolled in the ESC EORP PPCM Registry, the aim was to derive a prognostic model to predict LV recovery at 6 months and develop the \u2018ESC EORP PPCM Recovery Score\u2019\u2014a tool for clinicians to estimate the probability of LV recovery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>From 2012 to 2018, 752 women from 51 countries were enrolled. Eligibility included (i) a peripartum state, (ii) signs or symptoms of heart failure, (iii) LV ejection fraction (LVEF) \u2264 45%, and (iv) exclusion of alternative causes of heart failure. The model was derived using data from participants in the Registry and internally validated using bootstrap methods. The outcome was LV recovery (LVEF \u226550%) at six months. An integer score was created.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Overall, 465 women had a 6-month echocardiogram. LV recovery occurred in 216 (46.5%). The final model included baseline LVEF, baseline LV end diastolic diameter, human development index (a summary measure of a country\u2019s social and economic development), duration of symptoms, QRS duration and pre-eclampsia. The model was well-calibrated and had good discriminatory ability (C-statistic 0.79, 95% confidence interval [CI] 0.74\u20130.83). The model was internally validated (optimism-corrected C-statistic 0.78, 95% CI 0.73\u20130.82).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>A model which accurately predicts LV recovery at 6 months in women with PPCM was derived. The corresponding ESC EORP PPCM Recovery Score can be easily applied in clinical practice to predict the probability of LV recovery for an individual in order to guide tailored counselling and treatment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurheartj\/ehad888","type":"journal-article","created":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T08:22:56Z","timestamp":1706516576000},"page":"1430-1439","source":"Crossref","is-referenced-by-count":36,"title":["A novel score to predict left ventricular recovery in peripartum cardiomyopathy derived from the ESC EORP Peripartum Cardiomyopathy Registry"],"prefix":"10.1093","volume":"45","author":[{"given":"Alice M","family":"Jackson","sequence":"first","affiliation":[{"name":"BHF Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow , Glasgow , United 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Baghdad Heart Center , Medical City, Baghdad , Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hawani Sasmaya","family":"Prameswari","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, Hasan Sadikin General Hospital , Bandung , Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2976-2514","authenticated-orcid":false,"given":"Michael","family":"B\u00f6hm","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universit\u00e4tsklinikum des Saarlandes, Saarland University , Homburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4306-5317","authenticated-orcid":false,"given":"Pardeep S","family":"Jhund","sequence":"additional","affiliation":[{"name":"BHF Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow , Glasgow , United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aldo P","family":"Maggioni","sequence":"additional","affiliation":[{"name":"ANMCO Research Center, Heart Care Foundation , Firenze , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"van der Meer","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Medical Center Groningen, University of Groningen , Groningen , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8272-0911","authenticated-orcid":false,"given":"Karen","family":"Sliwa","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Department of Medicine and Cardiology University of Cape Town, Cape Heart Institute , Cape Town, South 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