{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T22:46:09Z","timestamp":1776725169491,"version":"3.51.2"},"reference-count":41,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T00:00:00Z","timestamp":1715385600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Dutch Ministry of Health with the innovation"},{"name":"Health Care Institute for conditional reimbursement"},{"DOI":"10.13039\/100001316","name":"Abbott Laboratories","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background and Aims<\/jats:title>\n                  <jats:p>In patients with chronic heart failure (HF), the MONITOR-HF trial demonstrated the efficacy of pulmonary artery (PA)-guided HF therapy over standard of care in improving quality of life and reducing HF hospitalizations and mean PA pressure. This study aimed to evaluate the consistency of these benefits in relation to clinically relevant subgroups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The effect of PA-guided HF therapy was evaluated in the MONITOR-HF trial among predefined subgroups based on age, sex, atrial fibrillation, diabetes mellitus, left ventricular ejection fraction, HF aetiology, cardiac resynchronization therapy, and implantable cardioverter defibrillator. Outcome measures were based upon significance in the main trial and included quality of life-, clinical-, and PA pressure endpoints, and were assessed for each subgroup. Differential effects in relation to the subgroups were assessed with interaction terms. Both unadjusted and multiple testing adjusted interaction terms were presented.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The effects of PA monitoring on quality of life, clinical events, and PA pressure were consistent in the predefined subgroups, without any clinically relevant heterogeneity within or across all endpoint categories (all adjusted interaction P-values were non-significant). In the unadjusted analysis of the primary endpoint quality-of-life change, weak trends towards a less pronounced effect in older patients (Pinteraction = .03; adjusted Pinteraction = .33) and diabetics (Pinteraction = .01; adjusted Pinteraction = .06) were observed. However, these interaction effects did not persist after adjusting for multiple testing.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This subgroup analysis confirmed the consistent benefits of PA-guided HF therapy observed in the MONITOR-HF trial across clinically relevant subgroups, highlighting its efficacy in improving quality of life, clinical, and PA pressure endpoints in chronic HF patients.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurheartj\/ehae323","type":"journal-article","created":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T08:18:24Z","timestamp":1715415504000},"source":"Crossref","is-referenced-by-count":5,"title":["Pulmonary artery pressure monitoring in chronic heart failure: effects across clinically relevant subgroups in the MONITOR-HF trial"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9752-6962","authenticated-orcid":false,"given":"Pascal R D","family":"Clephas","sequence":"first","affiliation":[{"name":"Department of Cardiology, Thorax Centre, Cardiovascular Institute, Erasmus University Medical Center , Dr. Molewaterplein 40, 3015GD Rotterdam , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor W","family":"Zwartkruis","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Medical Centre Groningen , Groningen , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jishnu","family":"Malgie","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Thorax Centre, Cardiovascular Institute, Erasmus University Medical Center , Dr. Molewaterplein 40, 3015GD Rotterdam , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco W F","family":"van Gent","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Albert Schweitzer Hospital , Dordrecht , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Peter","family":"Brunner-La Rocca","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Maastricht University Medical Centre , Maastricht , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariusz K","family":"Szymanski","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Medical Center Utrecht , Utrecht , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vokko P","family":"van Halm","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centre, University of Amsterdam , Amsterdam , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M Louis","family":"Handoko","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Medical Center Utrecht , Utrecht , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wouter E M","family":"Kok","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centre, University of Amsterdam , Amsterdam , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1692-8669","authenticated-orcid":false,"given":"Folkert W","family":"Asselbergs","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centre, University of Amsterdam , Amsterdam , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland R J","family":"van Kimmenade","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Radboud University Medical Centre , Nijmegen , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier C","family":"Manintveld","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Thorax Centre, Cardiovascular Institute, Erasmus University Medical Center , Dr. Molewaterplein 40, 3015GD Rotterdam , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas M D A","family":"van Mieghem","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Thorax Centre, Cardiovascular Institute, Erasmus University Medical Center , Dr. Molewaterplein 40, 3015GD Rotterdam , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1916-078X","authenticated-orcid":false,"given":"Saskia L M A","family":"Beeres","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Centre , Leiden , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco C","family":"Post","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Medical Center Utrecht , Utrecht , Netherlands"},{"name":"Department of Cardiology, St. Antonius Hospital , Nieuwegein , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C Jan Willem","family":"Borleffs","sequence":"additional","affiliation":[{"name":"Department of Cardiology, HAGA Hospital , Den Haag , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond","family":"Tukkie","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Spaarne Hospital , Haarlem , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arend","family":"Mosterd","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Meander Medical Centre , Amersfoort , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerard C M","family":"Linssen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Group Twente , Almelo , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruud F","family":"Spee","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Maxima Medical Centre , Veldhoven\/Eindhoven , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mireille E","family":"Emans","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ikazia Hospital , Rotterdam , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom D J","family":"Smilde","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Scheeper Hospital TREANT , Emmen , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"van Ramshorst","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Noordwest Hospital Group , Alkmaar , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles J H J","family":"Kirchhof","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Alrijne Hospital , Leiderdorp , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margriet W","family":"Feenema-Aardema","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Medical Centre Leeuwarden , Leeuwarden , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos A","family":"da Fonseca","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Medical Centre Leeuwarden , Leeuwarden , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mieke","family":"van den Heuvel","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Medisch Spectrum Twente , Enschede , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald","family":"Hazeleger","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Vie Curi Hospital , Venlo , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martijn","family":"van Eck","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Jeroen Bosch Hospital , \u2018s-Hertogenbosch , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loek","family":"van Heerebeek","sequence":"additional","affiliation":[{"name":"Department of Cardiology, OLVG Hospital , Amsterdam , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Boersma","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Thorax Centre, Cardiovascular Institute, Erasmus University Medical Center , Dr. Molewaterplein 40, 3015GD Rotterdam , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michiel","family":"Rienstra","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Medical Centre Groningen , Groningen , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolf A","family":"de Boer","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Thorax Centre, Cardiovascular Institute, Erasmus University Medical Center , Dr. Molewaterplein 40, 3015GD Rotterdam , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasper J","family":"Brugts","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Thorax Centre, Cardiovascular Institute, Erasmus University Medical Center , Dr. Molewaterplein 40, 3015GD Rotterdam , Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,5,11]]},"reference":[{"key":"2024062713092912500_ehae323-B1","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.cardfail.2021.12.017","article-title":"Economic issues in heart failure in the United States","volume":"28","author":"Heidenreich","year":"2022","journal-title":"J Card Fail"},{"key":"2024062713092912500_ehae323-B2","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1007\/s40273-020-00952-0","article-title":"A systematic review of medical costs associated with heart failure in the USA (2014\u20132020)","volume":"38","author":"Urbich","year":"2020","journal-title":"Pharmacoeconomics"},{"key":"2024062713092912500_ehae323-B3","doi-asserted-by":"crossref","first-page":"2911","DOI":"10.1093\/eurheartj\/ehad280","article-title":"Telemonitoring for heart failure: a meta-analysis","volume":"44","author":"Scholte","year":"2023","journal-title":"Eur Heart J"},{"key":"2024062713092912500_ehae323-B4","first-page":"S1050-1738(23)00111-1","article-title":"Benefits of remote hemodynamic monitoring in heart failure","author":"Clephas","year":"2023","journal-title":"Trends Cardiovasc Med"},{"key":"2024062713092912500_ehae323-B5","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.3390\/s23031364","article-title":"Recent advances in remote pulmonary artery pressure monitoring for patients with chronic heart failure: current evidence and future perspectives","volume":"23","author":"Clephas","year":"2023","journal-title":"Sensors (Basel)"},{"key":"2024062713092912500_ehae323-B6","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/S0140-6736(21)01754-2","article-title":"Haemodynamic-guided management of heart failure (GUIDE-HF): a randomised controlled trial","volume":"398","author":"Lindenfeld","year":"2021","journal-title":"Lancet"},{"key":"2024062713092912500_ehae323-B7","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/S0140-6736(11)60101-3","article-title":"Wireless pulmonary artery haemodynamic monitoring in chronic heart failure: a randomised controlled trial","volume":"377","author":"Abraham","year":"2011","journal-title":"Lancet"},{"key":"2024062713092912500_ehae323-B8","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0140-6736(15)00723-0","article-title":"Sustained efficacy of pulmonary artery pressure to guide adjustment of chronic heart failure therapy: complete follow-up results from the CHAMPION randomised trial","volume":"387","author":"Abraham","year":"2016","journal-title":"Lancet"},{"key":"2024062713092912500_ehae323-B9","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1002\/ejhf.1943","article-title":"Pulmonary artery pressure-guided therapy in ambulatory patients with symptomatic heart failure: the CardioMEMS European Monitoring Study for Heart Failure (MEMS-HF)","volume":"22","author":"Angermann","year":"2020","journal-title":"Eur J Heart Fail"},{"key":"2024062713092912500_ehae323-B10","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/ehf2.13748","article-title":"Real-world evidence in a national health service: results of the UK CardioMEMS HF system post-market study","volume":"9","author":"Cowie","year":"2022","journal-title":"ESC Heart Fail"},{"key":"2024062713092912500_ehae323-B11","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1016\/j.jacc.2017.03.009","article-title":"Ambulatory hemodynamic monitoring reduces heart failure hospitalizations in \u201creal-world\u201d clinical practice","volume":"69","author":"Desai","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2024062713092912500_ehae323-B12","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.cardfail.2022.10.422","article-title":"Sustained reduction in pulmonary artery pressures and hospitalizations during 2 years of ambulatory monitoring","volume":"29","author":"Heywood","year":"2023","journal-title":"J Card Fail"},{"key":"2024062713092912500_ehae323-B13","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1016\/S0140-6736(23)00923-6","article-title":"Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial","volume":"401","author":"Brugts","year":"2023","journal-title":"Lancet"},{"key":"2024062713092912500_ehae323-B14","doi-asserted-by":"crossref","first-page":"3658","DOI":"10.1093\/eurheartj\/ehad346","article-title":"Efficacy of pulmonary artery pressure monitoring in patients with chronic heart failure: a meta-analysis of three randomized controlled trials","volume":"44","author":"Clephas","year":"2023","journal-title":"Eur Heart J"},{"key":"2024062713092912500_ehae323-B15","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1016\/j.jacc.2017.08.010","article-title":"Pulmonary artery pressure-guided management of patients with heart failure and reduced ejection fraction","volume":"70","author":"Givertz","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2024062713092912500_ehae323-B16","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1161\/CIRCHEARTFAILURE.113.001229","article-title":"Wireless pulmonary artery pressure monitoring guides management to reduce decompensation in heart failure with preserved ejection fraction","volume":"7","author":"Adamson","year":"2014","journal-title":"Circ Heart Fail"},{"key":"2024062713092912500_ehae323-B17","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.jchf.2021.05.020","article-title":"Pulmonary artery pressure monitoring effectively guides management to reduce heart failure hospitalizations in obesity","volume":"9","author":"Brinkley","year":"2021","journal-title":"JACC Heart Fail"},{"key":"2024062713092912500_ehae323-B18","doi-asserted-by":"crossref","first-page":"e007892","DOI":"10.1161\/CIRCHEARTFAILURE.120.007892","article-title":"Remote hemodynamic monitoring equally reduces heart failure hospitalizations in women and men in clinical practice: a sex-specific analysis of the CardioMEMS post-approval study","volume":"14","author":"DeFilippis","year":"2021","journal-title":"Circ Heart Fail"},{"key":"2024062713092912500_ehae323-B19","doi-asserted-by":"crossref","first-page":"e009721","DOI":"10.1161\/CIRCHEARTFAILURE.122.009721","article-title":"Pulmonary artery pressure-guided heart failure management reduces hospitalizations in patients with chronic kidney disease","volume":"16","author":"Raval","year":"2023","journal-title":"Circ Heart Fail"},{"key":"2024062713092912500_ehae323-B20","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1002\/ejhf.2656","article-title":"Effects of remote haemodynamic-guided heart failure management in patients with different subtypes of pulmonary hypertension: insights from the MEMS-HF study","volume":"24","author":"Assmus","year":"2022","journal-title":"Eur J Heart Fail"},{"key":"2024062713092912500_ehae323-B21","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/eurheartj\/ehv317","article-title":"2015 ESC\/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: the joint task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT)","volume":"37","author":"Galie","year":"2016","journal-title":"Eur Heart J"},{"key":"2024062713092912500_ehae323-B22","volume-title":"Obesity and overweight","author":"World Health Organization"},{"key":"2024062713092912500_ehae323-B23","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1038\/s41433-022-01948-0","article-title":"When to believe a subgroup analysis: revisiting the 11 criteria","volume":"36","author":"Farrokhyar","year":"2022","journal-title":"Eye (Lond)"},{"key":"2024062713092912500_ehae323-B24","first-page":"65","article-title":"A simple sequentially rejective multiple test procedure","volume":"6","author":"Holm","year":"1979","journal-title":"Scand J Stat"},{"key":"2024062713092912500_ehae323-B25","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0895-4356(00)00314-0","article-title":"Adjusting for multiple testing\u2013when and how?","volume":"54","author":"Bender","year":"2001","journal-title":"J Clin Epidemiol"},{"key":"2024062713092912500_ehae323-B26","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1056\/NEJMp068070","article-title":"The challenge of subgroup analyses\u2013reporting without distorting","volume":"354","author":"Lagakos","year":"2006","journal-title":"N Engl J Med"},{"key":"2024062713092912500_ehae323-B27","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1016\/S0140-6736(05)66516-6","article-title":"Multiplicity in randomised trials II: subgroup and interim analyses","volume":"365","author":"Schulz","year":"2005","journal-title":"Lancet"},{"key":"2024062713092912500_ehae323-B28","doi-asserted-by":"crossref","first-page":"h5651","DOI":"10.1136\/bmj.h5651","article-title":"Three simple rules to ensure reasonably credible subgroup analyses","volume":"351","author":"Burke","year":"2015","journal-title":"BMJ"},{"key":"2024062713092912500_ehae323-B29","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1002\/ejhf.2033","article-title":"A current and future outlook on upcoming technologies in remote monitoring of patients with heart failure","volume":"23","author":"Bekfani","year":"2021","journal-title":"Eur J Heart Fail"},{"key":"2024062713092912500_ehae323-B30","doi-asserted-by":"crossref","first-page":"M57","DOI":"10.1093\/eurheartj\/suz214","article-title":"The trialist's perspective: what do you need to prove for remote monitoring devices to be approved?","volume":"21","author":"Angermann","year":"2019","journal-title":"Eur Heart J Suppl"},{"key":"2024062713092912500_ehae323-B31","doi-asserted-by":"crossref","DOI":"10.1002\/ejhf.3213","article-title":"Cost-effectiveness of remote haemodynamic monitoring by an implantable pulmonary artery pressure monitoring sensor (CardioMEMS-HF system) in chronic heart failure in the Netherlands","author":"Mokri","year":"2024","journal-title":"Eur J Heart Fail"},{"key":"2024062713092912500_ehae323-B32","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1002\/ejhf.642","article-title":"Pulmonary artery pressure-guided heart failure management: US cost-effectiveness analyses using the results of the CHAMPION clinical trial","volume":"19","author":"Martinson","year":"2017","journal-title":"Eur J Heart Fail"},{"key":"2024062713092912500_ehae323-B33","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/clc.22696","article-title":"Cost-effectiveness of remote cardiac monitoring with the CardioMEMS heart failure system","volume":"40","author":"Schmier","year":"2017","journal-title":"Clin Cardiol"},{"key":"2024062713092912500_ehae323-B34","doi-asserted-by":"crossref","first-page":"3046","DOI":"10.1002\/ehf2.14496","article-title":"Real-time pulmonary artery pressure monitoring in heart failure patients: an updated cost-effectiveness analysis","volume":"10","author":"Cowie","year":"2023","journal-title":"ESC Heart Fail"},{"key":"2024062713092912500_ehae323-B35","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.jacc.2023.11.030","article-title":"Implantable hemodynamic monitors improve survival in patients with heart failure and reduced ejection fraction","volume":"83","author":"Lindenfeld","year":"2024","journal-title":"J Am Coll Cardiol"},{"key":"2024062713092912500_ehae323-B36","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.jchf.2022.08.012","article-title":"Hemodynamically-Guided management of heart failure across the ejection fraction Spectrum: the GUIDE-HF trial","volume":"10","author":"Zile","year":"2022","journal-title":"JACC Heart Fail"},{"key":"2024062713092912500_ehae323-B37","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/j.jchf.2019.10.003","article-title":"Frailty among older decompensated heart failure patients: prevalence, association with patient-centered outcomes, and efficient detection methods","volume":"7","author":"Pandey","year":"2019","journal-title":"JACC Heart Fail"},{"key":"2024062713092912500_ehae323-B38","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1002\/jcsm.13306","article-title":"Frailty and heart failure: state-of-the-art review","volume":"14","author":"Talha","year":"2023","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"2024062713092912500_ehae323-B39","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.jchf.2019.09.004","article-title":"Impact of age on comorbidities and outcomes in heart failure with reduced ejection fraction","volume":"7","author":"Regan","year":"2019","journal-title":"JACC Heart Fail"},{"key":"2024062713092912500_ehae323-B40","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s12933-019-0885-2","article-title":"Relationship between frailty and mortality, hospitalization, and cardiovascular diseases in diabetes: a systematic review and meta-analysis","volume":"18","author":"Ida","year":"2019","journal-title":"Cardiovasc Diabetol"},{"key":"2024062713092912500_ehae323-B41","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1093\/eurheartj\/ehu202","article-title":"Pre-specified vs. Post-hoc subgroup analyses: are we wiser before or after a trial has been performed?","volume":"35","author":"Schuhlen","year":"2014","journal-title":"Eur Heart J"}],"container-title":["European Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eurheartj\/advance-article-pdf\/doi\/10.1093\/eurheartj\/ehae323\/57500805\/ehae323.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurheartj\/advance-article-pdf\/doi\/10.1093\/eurheartj\/ehae323\/58346488\/ehae323.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurheartj\/advance-article-pdf\/doi\/10.1093\/eurheartj\/ehae323\/58346488\/ehae323.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T13:21:58Z","timestamp":1719494518000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurheartj\/advance-article\/doi\/10.1093\/eurheartj\/ehae323\/7668040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,11]]},"references-count":41,"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/ehae323","relation":{},"ISSN":["0195-668X","1522-9645"],"issn-type":[{"value":"0195-668X","type":"print"},{"value":"1522-9645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,11]]},"article-number":"ehae323"}}