{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T11:01:41Z","timestamp":1776855701149,"version":"3.51.2"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"16","license":[{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,22]]},"DOI":"10.1093\/eurheartj\/ehaf908","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T11:23:45Z","timestamp":1763465025000},"page":"2003-2003","source":"Crossref","is-referenced-by-count":1,"title":["Low-dose, slow-infusion tPA is the treatment of choice for left-sided PVT"],"prefix":"10.1093","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2073-2917","authenticated-orcid":false,"given":"Ganesan","family":"Karthikeyan","sequence":"first","affiliation":[{"name":"24, Cardiothoracic Sciences Centre, All India Institute of Medical Sciences , New Delhi 110029 ,","place":["India"]},{"name":"Translational Health Science and Technology Institute , Faridabad ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,11,18]]},"reference":[{"key":"2026042119584433000_ehaf908-B1","doi-asserted-by":"publisher","first-page":"3373","DOI":"10.1093\/eurheartj\/ehaf391","article-title":"Urgent surgery vs fibrinolytic therapy for left-sided prosthetic valve thrombosis: a randomized trial","volume":"46","author":"Karthikeyan","year":"2025","journal-title":"Eur Heart J"},{"key":"2026042119584433000_ehaf908-B2","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1016\/j.jacc.2021.12.027","article-title":"Thrombolysis or surgery in patients with obstructive mechanical valve thrombosis: the multicenter HATTUSHA study","volume":"79","author":"Ozkan","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"2026042119584433000_ehaf908-B3","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/S1010-7940(03)00568-2","article-title":"Surgery for prosthetic valve obstruction. A single center study of 136 patients","volume":"24","author":"Roudaut","year":"2003","journal-title":"Eur J Cardiothorac Surg"},{"key":"2026042119584433000_ehaf908-B4","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.1016\/j.jacc.2014.12.062","article-title":"Spontaneous normalization of valve function after failed fibrinolytic therapy for left-sided prosthetic valve thrombosis","volume":"65","author":"Karthikeyan","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"2026042119584433000_ehaf908-B5","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1056\/NEJMoa2209051","article-title":"Rivaroxaban in rheumatic heart disease-associated atrial fibrillation","volume":"387","author":"Connolly","year":"2022","journal-title":"N Engl J Med"}],"container-title":["European Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eurheartj\/article-pdf\/47\/16\/2003\/65370024\/ehaf908.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurheartj\/article-pdf\/47\/16\/2003\/65370024\/ehaf908.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T23:58:48Z","timestamp":1776815928000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurheartj\/article\/47\/16\/2003\/8326469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,18]]},"references-count":5,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2025,11,18]]},"published-print":{"date-parts":[[2026,4,22]]}},"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/ehaf908","relation":{},"ISSN":["0195-668X","1522-9645"],"issn-type":[{"value":"0195-668X","type":"print"},{"value":"1522-9645","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,4,21]]},"published":{"date-parts":[[2025,11,18]]}}}