{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:04:40Z","timestamp":1792785880414,"version":"4.5.0"},"reference-count":149,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fonds de Recherche du Qu\u00e9bec\u2014Sant\u00e9","id":[{"id":"https:\/\/ror.org\/00w3qhf76","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Over the past decades, advances in the diagnosis and treatment of congenital heart disease have reshaped its epidemiology. Congenital heart disease is now increasingly a chronic, lifelong disorder, with adult survivors outnumbering affected children in many countries. This demographic transition has shifted the focus from preventing early mortality towards optimizing long-term health and managing comorbidities. Adult congenital heart disease (ACHD) experience acquired cardiovascular and systemic complications that challenge traditional models of care. As the lifelong burden of disease in ACHD patients continues to rise globally, advanced training pathways in ACHD have spearheaded the content expertise required to deliver high quality of care. The well-established hub-and-scope model has been recommended in the last two decades to improve ACHD care by expanding the number of specialized centres that allow ACHD specialists to reach underserved regions more effectively. However, the advent of technology, digital health, and artificial intelligence\u2013enhanced decision-making provides an opportunity to imagine a different approach, to coordinate advances in research, clinical care, and health system design, with particular emphasis on scalable models that align expertise, data, and delivery across the life course. Networked care structures, workforce redesign, and digitally enabled learning health systems offer a pathway to close persistent gaps in care access and quality. Ultimately, the future of ACHD care will depend on our ability to integrate these innovations into routine practice, ensuring that extended survival is matched by preserved function, quality of life, and equitable outcomes at the population scale.<\/jats:p>","DOI":"10.1093\/eurheartj\/ehag616","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T11:56:23Z","timestamp":1784807783000},"source":"Crossref","is-referenced-by-count":0,"title":["Congenital heart disease in adults: evolving health systems and lifelong outcomes"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3050-5248","authenticated-orcid":false,"given":"Gerhard-Paul","family":"Diller","sequence":"first","affiliation":[{"name":"Department of Cardiology III\u2014Adult Congenital and Valvular Heart Disease, University Hospital Muenster , Albert-Schweitzer-Campus 1, Muenster ,","place":["Germany"]},{"name":"Adult Congenital Heart Centre, Royal Brompton Hospital, Guy\u2019s and St Thomas\u2019s NHS Foundation Trust, Imperial College , London ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4201-6337","authenticated-orcid":false,"given":"Curt","family":"Daniels","sequence":"additional","affiliation":[{"name":"The Adult Congenital Heart Program, The Ohio State University , Columbus, OH ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1784-8206","authenticated-orcid":false,"given":"Ariane","family":"Marelli","sequence":"additional","affiliation":[{"name":"McGill Adult Unit for Congenital Heart Disease , McGill University Health Centre, Montreal, Quebec H4A 3J1 ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,10,5]]},"reference":[{"key":"2026100502565768400_ehag616-B1","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1001\/jama.2018.12621","article-title":"From lifespan to healthspan","volume":"320","author":"Olshansky","year":"2018","journal-title":"JAMA"},{"key":"2026100502565768400_ehag616-B2","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1093\/geront\/gnv130","article-title":"Lifespan and healthspan: past, present, and promise","volume":"55","author":"Crimmins","year":"2015","journal-title":"Gerontologist"},{"key":"2026100502565768400_ehag616-B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacadv.2022.100012","article-title":"Born to age: when adult congenital heart disease converges with geroscience","volume":"1","author":"Moons","year":"2022","journal-title":"JACC Adv"},{"key":"2026100502565768400_ehag616-B4","doi-asserted-by":"publisher","first-page":"2241","DOI":"10.1016\/j.jacc.2011.08.025","article-title":"Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis","volume":"58","author":"van der Linde","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"2026100502565768400_ehag616-B5","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1093\/ije\/dyz009","article-title":"Global birth prevalence of congenital heart defects 1970-2017: updated systematic review and meta-analysis of 260 studies","volume":"48","author":"Liu","year":"2019","journal-title":"Int J Epidemiol"},{"key":"2026100502565768400_ehag616-B6","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1111\/chd.12176","article-title":"Temporal variation of birth prevalence of congenital heart disease in the United States","volume":"10","author":"Egbe","year":"2015","journal-title":"Congenit Heart Dis"},{"key":"2026100502565768400_ehag616-B7","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1289\/EHP171","article-title":"Risk of congenital heart defects after ambient heat exposure early in pregnancy","volume":"125","author":"Auger","year":"2017","journal-title":"Environ Health Perspect"},{"key":"2026100502565768400_ehag616-B8","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1161\/CIRCULATIONAHA.112.001054","article-title":"Association between maternal chronic conditions and congenital heart defects: a population-based cohort study","volume":"128","author":"Liu","year":"2013","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B9","doi-asserted-by":"publisher","first-page":"29","DOI":"10.2147\/tacg.s8794","article-title":"Congenital malformations in Ecuadorian children: urgent need to create a national registry of birth defects","volume":"3","author":"Gonzalez-Andrade","year":"2010","journal-title":"Appl Clin Genet"},{"key":"2026100502565768400_ehag616-B10","doi-asserted-by":"publisher","first-page":"1404","DOI":"10.1002\/bdr2.2117","article-title":"Prevalence of congenital heart defects in Europe, 2008-2015: a registry-based study","volume":"114","author":"Mamasoula","year":"2022","journal-title":"Birth Defects Res"},{"key":"2026100502565768400_ehag616-B11","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1111\/j.1365-3016.2008.00987.x","article-title":"Descriptive epidemiology of congenital heart disease in Northern England","volume":"23","author":"Dadvand","year":"2009","journal-title":"Paediatr Perinat Epidemiol"},{"key":"2026100502565768400_ehag616-B12","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1016\/j.ahj.2008.10.017","article-title":"National time trends in congenital heart defects, Denmark, 1977-2005","volume":"157","author":"Oyen","year":"2009","journal-title":"Am Heart J"},{"key":"2026100502565768400_ehag616-B13","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1161\/CIRCULATIONAHA.116.021793","article-title":"Congenital heart defects and indices of placental and fetal growth in a nationwide study of 924 422 liveborn infants","volume":"134","author":"Matthiesen","year":"2016","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B14","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2013-004244","article-title":"Trends in the prevalences of congenital anomalies and age at motherhood in a Southern European region: a population-based study","volume":"4","author":"Cambra","year":"2014","journal-title":"BMJ Open"},{"key":"2026100502565768400_ehag616-B15","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1159\/000091488","article-title":"Epidemiological characterization of congenital heart disease in Sao Miguel Island, Azores, Portugal","volume":"9","author":"Cymbron","year":"2006","journal-title":"Community Genet"},{"key":"2026100502565768400_ehag616-B16","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.pepo.2012.10.001","article-title":"The congenital malformations in children aged 0-2 in Zielona G\u00f3ra province (1988-1997) and Lubuskie province (1998-2007) according to the Polish registry of congenital malformations. Part 3. Age of mother and frequency of congenital malformations in children","volume":"88","author":"Pa\u015bnicki","year":"2013","journal-title":"Pediatr Pol"},{"key":"2026100502565768400_ehag616-B17","first-page":"36","article-title":"[Prevalence, mortality and lethality of congenital heart defects from the Tuscan registry (Tuscany Region, Central Italy), 1992-2009]","volume":"39","author":"Baldacci","year":"2015","journal-title":"Epidemiol Prev"},{"key":"2026100502565768400_ehag616-B18","doi-asserted-by":"publisher","first-page":"139","DOI":"10.3390\/medicina44020018","article-title":"[The incidence and diagnostics of congenital heart defects in Kaunas infant population during 1999-2005]","volume":"44","author":"Dulskiene","year":"2008","journal-title":"Medicina (Kaunas)"},{"key":"2026100502565768400_ehag616-B19","first-page":"81","article-title":"Distribution of congenital heart disease in Croatia and outcome analysis. A Croatian epidemiological study (2002-2007)","volume":"133","author":"Malcic","year":"2011","journal-title":"Lijec Vjesn"},{"key":"2026100502565768400_ehag616-B20","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1093\/eurjpc\/zwac227","article-title":"Congenital heart disease: changes in recorded birth prevalence and cardiac interventions over the past half-century in Sweden","volume":"30","author":"Giang","year":"2023","journal-title":"Eur J Prev Cardiol"},{"key":"2026100502565768400_ehag616-B21","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1007\/s10654-020-00653-0","article-title":"Birth prevalence of congenital heart disease in China, 1980\u20132019: a systematic review and meta-analysis of 617 studies","volume":"35","author":"Zhao","year":"2020","journal-title":"Eur J Epidemiol"},{"key":"2026100502565768400_ehag616-B22","doi-asserted-by":"publisher","DOI":"10.34172\/ijhpm.2024.7931","article-title":"Spatial distribution and birth prevalence of congenital heart disease in Iran: a systematic review and hierarchical Bayesian meta-analysis","volume":"13","author":"Farhadi Hassankiadeh","year":"2024","journal-title":"Int J Health Policy Manag"},{"key":"2026100502565768400_ehag616-B23","doi-asserted-by":"publisher","first-page":"2595","DOI":"10.1186\/s12889-025-23800-2","article-title":"The burden of congenital heart disease in Malaysia: a comprehensive review and meta-analytic synthesis, 1970\u20132024","volume":"25","author":"Kong","year":"2025","journal-title":"BMC Public Health"},{"key":"2026100502565768400_ehag616-B24","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1007\/s100380050102","article-title":"Prevalence of congenital malformations and genetic diseases in Korea","volume":"44","author":"Jung","year":"1999","journal-title":"J Hum Genet"},{"key":"2026100502565768400_ehag616-B25","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1007\/s10654-023-00971-z","article-title":"Accuracy of congenital anomaly coding in live birth children recorded in European health care databases, a EUROlinkCAT study","volume":"38","author":"Bakker","year":"2023","journal-title":"Eur J Epidemiol"},{"key":"2026100502565768400_ehag616-B26","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.athoracsur.2025.06.049","article-title":"Variation of prenatal detection of congenital heart disease in infants: updated analysis of The Society of Thoracic Surgeons Congenital Heart Surgery database","volume":"121","author":"Ribeiro","year":"2026","journal-title":"Ann Thorac Surg"},{"key":"2026100502565768400_ehag616-B27","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1186\/s12884-025-07612-1","article-title":"Global, regional, and national epidemiology of congenital birth defects in children from 1990 to 2021: a cross-sectional study","volume":"25","author":"Li","year":"2025","journal-title":"BMC Pregnancy Childbirth"},{"key":"2026100502565768400_ehag616-B28","doi-asserted-by":"publisher","first-page":"e019","DOI":"10.25259\/IJMA_44_2024","article-title":"Burden of fetal anomalies among antenatal mothers attending a public referral hospital: a mixed cohort study","volume":"14","author":"Fotedar","year":"2025","journal-title":"Int J MCH AIDS"},{"key":"2026100502565768400_ehag616-B29","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1161\/CIRCULATIONAHA.106.627224","article-title":"Congenital heart disease in the general population: changing prevalence and age distribution","volume":"115","author":"Marelli","year":"2007","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B30","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1161\/circresaha.116.309302","article-title":"Changing landscape of congenital heart disease","volume":"120","author":"Bouma","year":"2017","journal-title":"Circ Res"},{"key":"2026100502565768400_ehag616-B31","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1001\/jamainternmed.2016.7765","article-title":"Survivorship in children and young adults with congenital heart disease in Sweden","volume":"177","author":"Mandalenakis","year":"2017","journal-title":"JAMA Intern Med"},{"key":"2026100502565768400_ehag616-B32","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1016\/j.jacc.2010.03.085","article-title":"Changing mortality in congenital heart disease","volume":"56","author":"Khairy","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"2026100502565768400_ehag616-B33","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1016\/j.ahj.2009.08.014","article-title":"Mortality associated with adult congenital heart disease: trends in the US population from 1979 to 2005","volume":"158","author":"Pillutla","year":"2009","journal-title":"Am Heart J"},{"key":"2026100502565768400_ehag616-B34","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2022-056294","article-title":"Lesion-specific congenital heart disease mortality trends in children: 1999 to 2017","volume":"150","author":"Lynn","year":"2022","journal-title":"Pediatrics"},{"key":"2026100502565768400_ehag616-B35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacadv.2025.101812","article-title":"Longitudinal trends in pediatric survival by congenital heart defect in Texas, 1999 to 2017","volume":"4","author":"Stephens","year":"2025","journal-title":"JACC Adv"},{"key":"2026100502565768400_ehag616-B36","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/s2352-4642(19)30402-x","article-title":"Global, regional, and national burden of congenital heart disease, 1990-2017: a systematic analysis for the global burden of disease study 2017","volume":"4","author":"GBD 2017 Congenital Heart Disease Collaborators","year":"2020","journal-title":"Lancet Child Adolesc Health"},{"key":"2026100502565768400_ehag616-B37","volume-title":"Operational Framework for Monitoring Social Determinants of Health Equity","author":"Organization","year":"2024"},{"key":"2026100502565768400_ehag616-B38","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1016\/S0140-6736(06)68337-2","article-title":"Mortality of HIV-1-infected patients in the first year of antiretroviral therapy: comparison between low-income and high-income countries","volume":"367","author":"Braitstein","year":"2006","journal-title":"Lancet"},{"key":"2026100502565768400_ehag616-B39","volume-title":"Congenital Heart Defects-Recent Advances","author":"Elshazali","year":"2022"},{"key":"2026100502565768400_ehag616-B40","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh-2023-012049","article-title":"Recommendations for developing effective and safe paediatric and congenital heart disease services in low-income and middle-income countries: a public health framework","volume":"8","author":"Hasan","year":"2023","journal-title":"BMJ Glob Health"},{"key":"2026100502565768400_ehag616-B41","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1186\/s12884-025-07617-w","article-title":"Trends in burden and mortality of congenital birth defects in G20 countries (1990-2021) and predictions for 2022-2040","volume":"25","author":"Li","year":"2025","journal-title":"BMC Pregnancy Childbirth"},{"key":"2026100502565768400_ehag616-B42","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2025.1601620","article-title":"Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050","volume":"13","author":"Ye","year":"2025","journal-title":"Front Pediatr"},{"key":"2026100502565768400_ehag616-B43","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.jtcvs.2021.01.134","article-title":"Long-term outcomes of the arterial switch operation","volume":"163","author":"Fricke","year":"2022","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2026100502565768400_ehag616-B44","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1161\/circulationaha.113.008396","article-title":"Lifetime prevalence of congenital heart disease in the general population from 2000 to 2010","volume":"130","author":"Marelli","year":"2014","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B45","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1186\/s12963-015-0063-z","article-title":"Projected growth of the adult congenital heart disease population in the United States to 2050: an integrative systems modeling approach","volume":"13","author":"Benziger","year":"2015","journal-title":"Popul Health Metr"},{"key":"2026100502565768400_ehag616-B46","doi-asserted-by":"publisher","DOI":"10.1161\/jaha.117.007907","article-title":"Adult congenital heart disease in a nationwide population 2000-2014: epidemiological trends, arrhythmia, and standardized mortality ratio","volume":"7","author":"Wu","year":"2018","journal-title":"J Am Heart Assoc"},{"key":"2026100502565768400_ehag616-B47","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.ijcard.2009.05.032","article-title":"Prevalence of adult patients with congenital heart disease in Japan","volume":"146","author":"Shiina","year":"2011","journal-title":"Int J Cardiol"},{"key":"2026100502565768400_ehag616-B48","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1038\/s41569-022-00749-y","article-title":"Changing epidemiology of congenital heart disease: effect on outcomes and quality of care in adults","volume":"20","author":"Liu","year":"2023","journal-title":"Nat Rev Cardiol"},{"key":"2026100502565768400_ehag616-B49","doi-asserted-by":"publisher","first-page":"2237","DOI":"10.1016\/j.jacc.2016.03.477","article-title":"Quality of life of adults with congenital heart disease in 15 countries: evaluating country-specific characteristics","volume":"67","author":"Apers","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"2026100502565768400_ehag616-B50","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2024.114156","article-title":"Wellbeing in children and adolescents with Fontan physiology","volume":"273","author":"Marshall","year":"2024","journal-title":"J Pediatr"},{"key":"2026100502565768400_ehag616-B51","doi-asserted-by":"publisher","first-page":"2092","DOI":"10.1016\/j.jacc.2024.02.055","article-title":"Clinical risk assessment and prediction in congenital heart disease across the lifespan: JACC scientific statement","volume":"83","author":"Opotowsky","year":"2024","journal-title":"J Am Coll Cardiol"},{"key":"2026100502565768400_ehag616-B52","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.ijcard.2015.04.230","article-title":"The care of adults with congenital heart disease across the globe: current assessment and future perspective: a position statement from the International Society for Adult Congenital Heart Disease (ISACHD)","volume":"195","author":"Webb","year":"2015","journal-title":"Int J Cardiol"},{"key":"2026100502565768400_ehag616-B53","doi-asserted-by":"publisher","first-page":"1609","DOI":"10.1016\/j.cjca.2019.09.015","article-title":"The future of adult congenital heart disease research: precision health services delivery for the next decade","volume":"35","author":"Marelli","year":"2019","journal-title":"Can J Cardiol"},{"key":"2026100502565768400_ehag616-B54","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1111\/joim.13048","article-title":"Trajectories of care in congenital heart disease\u2013the long arm of disease in the womb","volume":"288","author":"Marelli","year":"2020","journal-title":"J Intern Med"},{"key":"2026100502565768400_ehag616-B55","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1016\/S2352-4642(23)00053-6","article-title":"Improving long-term care and outcomes of congenital heart disease: fulfilling the promise of a healthy life","volume":"7","author":"Su","year":"2023","journal-title":"Lancet Child Adolesc Health"},{"key":"2026100502565768400_ehag616-B56","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1007\/s11886-025-02307-7","article-title":"Toward providing equitable care for adults with congenital heart disease: where we are and where we need to be","volume":"27","author":"Lin","year":"2025","journal-title":"Curr Cardiol Rep"},{"key":"2026100502565768400_ehag616-B57","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1161\/CIRCULATIONAHA.122.060834","article-title":"Adults with congenital heart disease: trends in event-free survival past middle age","volume":"147","author":"Dellborg","year":"2023","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B58","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1093\/eurheartj\/eht358","article-title":"Geriatric congenital heart disease: a new challenge in the care of adults with congenital heart disease?","volume":"35","author":"Baumgartner","year":"2014","journal-title":"Eur Heart J"},{"key":"2026100502565768400_ehag616-B59","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.hlc.2020.05.114","article-title":"Adult congenital heart disease survivors at age 50 years: medical and psychosocial Status","volume":"30","author":"Rehan","year":"2021","journal-title":"Heart Lung Circ"},{"key":"2026100502565768400_ehag616-B60","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.33963\/KP.a2021.0129","article-title":"The burden of cardiovascular risk factors among seniors with congenital heart disease: a single tertiary center experience","volume":"79","author":"Kwiatek-Wrzosek","year":"2021","journal-title":"Kardiol Pol"},{"key":"2026100502565768400_ehag616-B61","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1016\/j.jacc.2011.06.041","article-title":"Geriatric congenital heart disease: burden of disease and predictors of mortality","volume":"58","author":"Afilalo","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"2026100502565768400_ehag616-B62","doi-asserted-by":"publisher","first-page":"2219","DOI":"10.1016\/j.jacc.2021.03.012","article-title":"Lifespan perspective on congenital heart disease research: JACC state-of-the-art review","volume":"77","author":"Diller","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"2026100502565768400_ehag616-B63","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1161\/CIRCULATIONAHA.123.066983","article-title":"Adult congenital heart disease","volume":"149","author":"Dellborg","year":"2024","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B64","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacadv.2025.102081","article-title":"Critical care of the adult with congenital heart disease","volume":"4","author":"Valle","year":"2025","journal-title":"JACC Adv"},{"key":"2026100502565768400_ehag616-B65","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.ijcard.2020.08.039","article-title":"Risk prediction models for heart failure admissions in adults with congenital heart disease","volume":"322","author":"Cohen","year":"2021","journal-title":"Int J Cardiol"},{"key":"2026100502565768400_ehag616-B66","doi-asserted-by":"publisher","first-page":"2487","DOI":"10.1016\/j.ijcard.2013.03.003","article-title":"Heart failure admissions in adults with congenital heart disease; risk factors and prognosis","volume":"168","author":"Zomer","year":"2013","journal-title":"Int J Cardiol"},{"key":"2026100502565768400_ehag616-B67","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.122.009675","article-title":"Incidence and outcomes of advanced heart failure in adults with congenital heart disease","volume":"15","author":"Egbe","year":"2022","journal-title":"Circ Heart Fail"},{"key":"2026100502565768400_ehag616-B68","doi-asserted-by":"publisher","first-page":"1679","DOI":"10.1161\/CIRCULATIONAHA.109.866319","article-title":"Atrial arrhythmias in adults with congenital heart disease","volume":"120","author":"Bouchardy","year":"2009","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B69","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1093\/eurheartj\/ehaf466","article-title":"Arrhythmias in congenitally corrected transposition of the great arteries: an international study","volume":"47","author":"Sellal","year":"2026","journal-title":"Eur Heart J"},{"key":"2026100502565768400_ehag616-B70","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1016\/j.jacc.2007.10.043","article-title":"Mechanisms, prevention, and treatment of atrial fibrillation after cardiac surgery","volume":"51","author":"Echahidi","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"2026100502565768400_ehag616-B71","doi-asserted-by":"publisher","first-page":"2103","DOI":"10.1093\/eurheartj\/ehac104","article-title":"Sudden cardiac death in congenital heart disease","volume":"43","author":"Khairy","year":"2022","journal-title":"Eur Heart J"},{"key":"2026100502565768400_ehag616-B72","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1093\/europace\/euw060","article-title":"Sudden cardiac death in adult congenital heart disease: can the unpredictable be foreseen?","volume":"19","author":"Koyak","year":"2017","journal-title":"Europace"},{"key":"2026100502565768400_ehag616-B73","doi-asserted-by":"publisher","first-page":"1944","DOI":"10.1161\/CIRCULATIONAHA.112.104786","article-title":"Sudden cardiac death in adult congenital heart disease","volume":"126","author":"Koyak","year":"2012","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B74","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1136\/heartjnl-2020-316791","article-title":"Predicting sudden cardiac death in adults with congenital heart disease","volume":"107","author":"Oliver","year":"2021","journal-title":"Heart"},{"key":"2026100502565768400_ehag616-B75","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1016\/j.jtcvs.2006.03.057","article-title":"Impaired cardiac autonomic nervous activity predicts sudden cardiac death in patients with operated and unoperated congenital cardiac disease","volume":"132","author":"Lammers","year":"2006","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2026100502565768400_ehag616-B76","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1016\/j.ijcard.2014.04.072","article-title":"Contemporary prevalence of pulmonary arterial hypertension in adult congenital heart disease following the updated clinical classification","volume":"174","author":"van Riel","year":"2014","journal-title":"Int J Cardiol"},{"key":"2026100502565768400_ehag616-B77","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/j.jjcc.2022.07.019","article-title":"Status of adult outpatients with congenital heart disease in Japan: the Japanese network of cardiovascular departments for adult congenital heart disease registry","volume":"80","author":"Yao","year":"2022","journal-title":"J Cardiol"},{"key":"2026100502565768400_ehag616-B78","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.121.022596","article-title":"Pulmonary hypertension in adult congenital heart disease in Asia: a distinctive feature of Complex congenital heart disease","volume":"11","author":"Chiu","year":"2022","journal-title":"J Am Heart Assoc"},{"key":"2026100502565768400_ehag616-B79","doi-asserted-by":"publisher","first-page":"2385","DOI":"10.1161\/circulationaha.115.011241","article-title":"Stroke in adults with congenital heart disease: incidence, cumulative risk, and predictors","volume":"132","author":"Lanz","year":"2015","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B80","doi-asserted-by":"publisher","first-page":"1912","DOI":"10.1161\/CIRCULATIONAHA.117.029686","article-title":"Risk of dementia in adults with congenital heart disease: population-based cohort study","volume":"137","author":"Bagge","year":"2018","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B81","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.ijcard.2021.05.001","article-title":"Neurocognitive disorders amongst patients with congenital heart disease undergoing procedures in childhood","volume":"336","author":"Sterling","year":"2021","journal-title":"Int J Cardiol"},{"key":"2026100502565768400_ehag616-B82","doi-asserted-by":"publisher","first-page":"1928","DOI":"10.1056\/NEJMoa067393","article-title":"Abnormal brain development in newborns with congenital heart disease","volume":"357","author":"Miller","year":"2007","journal-title":"N Engl J Med"},{"key":"2026100502565768400_ehag616-B83","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1016\/S1474-4422(10)70112-5","article-title":"Cognitive deficits and associated neurological complications in individuals with Down's syndrome","volume":"9","author":"Lott","year":"2010","journal-title":"Lancet Neurol"},{"key":"2026100502565768400_ehag616-B84","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/ejhf.631","article-title":"Heart failure and risk of dementia: a Danish nationwide population-based cohort study","volume":"19","author":"Adelborg","year":"2017","journal-title":"Eur J Heart Fail"},{"key":"2026100502565768400_ehag616-B85","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1161\/STROKEAHA.116.015242","article-title":"Long-term risk of dementia among survivors of ischemic or hemorrhagic stroke","volume":"48","author":"Corraini","year":"2017","journal-title":"Stroke"},{"key":"2026100502565768400_ehag616-B86","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.ijcard.2010.08.030","article-title":"Measures of exercise capacity in adults with congenital heart disease","volume":"153","author":"Buys","year":"2011","journal-title":"Int J Cardiol"},{"key":"2026100502565768400_ehag616-B87","doi-asserted-by":"publisher","first-page":"1514","DOI":"10.1093\/brain\/awu041","article-title":"Cardiovascular and cognitive fitness at age 18 and risk of early-onset dementia","volume":"137","author":"Nyberg","year":"2014","journal-title":"Brain"},{"key":"2026100502565768400_ehag616-B88","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.amjcard.2022.05.031","article-title":"Prevalence of metabolic syndrome in young adults with congenital heart disease","volume":"179","author":"Umapathi","year":"2022","journal-title":"Am J Cardiol"},{"key":"2026100502565768400_ehag616-B89","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.114.001132","article-title":"Metabolic syndrome in adults with congenital heart disease","volume":"5","author":"Deen","year":"2016","journal-title":"J Am Heart Assoc"},{"key":"2026100502565768400_ehag616-B90","doi-asserted-by":"publisher","first-page":"e375","DOI":"10.3346\/jkms.2023.38.e375","article-title":"Prognosis of chronic kidney disease and metabolic syndrome in adults with congenital heart disease","volume":"38","author":"Jang","year":"2023","journal-title":"J Korean Med Sci"},{"key":"2026100502565768400_ehag616-B91","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.115.003076","article-title":"Congenital heart disease with and without cyanotic potential and the long-term risk of diabetes Mellitus: a population-based follow-up study","volume":"5","author":"Madsen","year":"2016","journal-title":"J Am Heart Assoc"},{"key":"2026100502565768400_ehag616-B92","doi-asserted-by":"publisher","DOI":"10.1093\/ehjopen\/oeac055","article-title":"Chronic kidney disease in patients with congenital heart disease: a nationwide, register-based cohort study","volume":"2","author":"Gillesen","year":"2022","journal-title":"Eur Heart J Open"},{"key":"2026100502565768400_ehag616-B93","doi-asserted-by":"publisher","first-page":"2320","DOI":"10.1161\/CIRCULATIONAHA.107.734921","article-title":"Prevalence, predictors, and prognostic value of renal dysfunction in adults with congenital heart disease","volume":"117","author":"Dimopoulos","year":"2008","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B94","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/s40697-015-0063-8","article-title":"Chronic kidney disease in congenital heart disease patients: a narrative review of evidence","volume":"2","author":"Morgan","year":"2015","journal-title":"Can J Kidney Health Dis"},{"key":"2026100502565768400_ehag616-B95","doi-asserted-by":"publisher","first-page":"1742","DOI":"10.1016\/j.amjcard.2016.08.057","article-title":"Prevalence of cancer in adults with congenital heart disease compared with the general population","volume":"118","author":"Gurvitz","year":"2016","journal-title":"Am J Cardiol"},{"key":"2026100502565768400_ehag616-B96","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0116844","article-title":"The risk of cancer in patients with congenital heart disease: a nationwide population-based cohort study in Taiwan","volume":"10","author":"Lee","year":"2015","journal-title":"PLoS One"},{"key":"2026100502565768400_ehag616-B97","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2019.6762","article-title":"Risk of Cancer among children and young adults with congenital heart disease compared with healthy controls","volume":"2","author":"Mandalenakis","year":"2019","journal-title":"JAMA Netw Open"},{"key":"2026100502565768400_ehag616-B98","doi-asserted-by":"publisher","first-page":"1334","DOI":"10.1161\/circulationaha.117.029138","article-title":"Exposure to low-dose ionizing radiation from cardiac procedures and malignancy risk in adults with congenital heart disease","volume":"137","author":"Cohen","year":"2018","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B99","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1093\/aje\/kwz114","article-title":"Flexible modeling of the association between cumulative exposure to low-dose ionizing radiation from cardiac procedures and risk of cancer in adults with congenital heart disease","volume":"188","author":"Danieli","year":"2019","journal-title":"Am J Epidemiol"},{"key":"2026100502565768400_ehag616-B100","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.122.026604","article-title":"CanCHD study of hematopoietic cancers in children with and without genetic syndromes","volume":"13","author":"Hasan","year":"2024","journal-title":"J Am Heart Assoc"},{"key":"2026100502565768400_ehag616-B101","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/j.jacc.2023.10.043","article-title":"Anxiety and depression in adults with congenital heart disease","volume":"83","author":"Kovacs","year":"2024","journal-title":"J Am Coll Cardiol"},{"key":"2026100502565768400_ehag616-B102","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1002\/bdr2.1971","article-title":"Post-traumatic stress disorder, anxiety, and depression among adults with congenital heart defects","volume":"114","author":"Simeone","year":"2022","journal-title":"Birth Defects Res"},{"key":"2026100502565768400_ehag616-B103","doi-asserted-by":"publisher","DOI":"10.1161\/jaha.119.014820","article-title":"Prevalence and prognostic association of a clinical diagnosis of depression in adult congenital heart disease: results of the Boston adult congenital heart disease biobank","volume":"9","author":"Carazo","year":"2020","journal-title":"J Am Heart Assoc"},{"key":"2026100502565768400_ehag616-B104","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1016\/j.amjcard.2015.11.065","article-title":"Prevalence and correlates of post-traumatic stress disorder in adults with congenital heart disease","volume":"117","author":"Deng","year":"2016","journal-title":"Am J Cardiol"},{"key":"2026100502565768400_ehag616-B105","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.jacc.2020.05.025","article-title":"Characteristics of adults with congenital heart defects in the United States","volume":"76","author":"Gurvitz","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"2026100502565768400_ehag616-B106","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/j.pcad.2018.08.002","article-title":"Neurocognitive impairment and its long-term impact on adults with congenital heart disease","volume":"61","author":"Cohen","year":"2018","journal-title":"Prog Cardiovasc Dis"},{"key":"2026100502565768400_ehag616-B107","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1016\/j.cjca.2022.03.021","article-title":"Canadian Cardiovascular Society 2022 guidelines for cardiovascular interventions in adults with congenital heart disease","volume":"38","author":"Marelli","year":"2022","journal-title":"Can J Cardiol"},{"key":"2026100502565768400_ehag616-B108","doi-asserted-by":"publisher","first-page":"e18","DOI":"10.1161\/CIR.0000000000001078","article-title":"Life's essential 8: updating and enhancing the American Heart Association's construct of cardiovascular health: a presidential advisory from the American Heart Association","volume":"146","author":"Lloyd-Jones","year":"2022","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B109","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1056\/NEJM199609193351213","article-title":"Part 1: quality of care\u2013what is it?","volume":"335","author":"Blumenthal","year":"1996","journal-title":"N Engl J Med"},{"key":"2026100502565768400_ehag616-B110","doi-asserted-by":"publisher","first-page":"100563","DOI":"10.1016\/j.ijcchd.2024.100563","article-title":"Toronto ACHD program: a 65 year legacy","volume":"19","author":"Colman","year":"2025","journal-title":"Int J Cardiol Congenit Heart Dis"},{"key":"2026100502565768400_ehag616-B111"},{"key":"2026100502565768400_ehag616-B112","author":"Directory AC"},{"key":"2026100502565768400_ehag616-B113","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.cjca.2023.08.004","article-title":"Adult congenital heart disease care in Canada: has quality of care improved in the last decade?","volume":"40","author":"Ducas","year":"2024","journal-title":"Can J Cardiol"},{"key":"2026100502565768400_ehag616-B114","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1093\/eurheartj\/eht572","article-title":"Recommendations for organization of care for adults with congenital heart disease and for training in the subspecialty of \u2018grown-up congenital heart disease\u2019 in Europe: a position paper of the working group on grown-up congenital heart disease of the European Society of Cardiology","volume":"35","author":"Baumgartner","year":"2014","journal-title":"Eur Heart J"},{"key":"2026100502565768400_ehag616-B115","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2023-002558","article-title":"Adult congenital heart disease training in Europe: current status, disparities and potential solutions","volume":"10","author":"McMahon","year":"2023","journal-title":"Open Heart"},{"key":"2026100502565768400_ehag616-B116","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/j.hlc.2018.10.015","article-title":"Adult congenital heart disease in Australia and New Zealand: a call for optimal care","volume":"28","author":"Nicolae","year":"2019","journal-title":"Heart Lung Circ"},{"key":"2026100502565768400_ehag616-B117"},{"key":"2026100502565768400_ehag616-B118","author":"Specialists and training centers"},{"key":"2026100502565768400_ehag616-B119","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcchd.2023.100461","article-title":"Position statement for the development of adult congenital heart disease units in Latin America and the Caribbean: recommendations by the adult congenital heart disease chapter and pediatric cardiology council of the interamerican society of cardiology","volume":"13","author":"Araujo","year":"2023","journal-title":"Int J Cardiol Congenit Heart Dis"},{"key":"2026100502565768400_ehag616-B120","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.1016\/s0735-1097(01)01280-3","article-title":"Care of the adult with congenital heart disease: introduction","volume":"37","author":"Webb","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"2026100502565768400_ehag616-B121","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ahj.2008.08.029","article-title":"Planning the specialized care of adult congenital heart disease patients: from numbers to guidelines; an epidemiologic approach","volume":"157","author":"Marelli","year":"2009","journal-title":"Am Heart J"},{"key":"2026100502565768400_ehag616-B122","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.ijcard.2019.04.077","article-title":"Staffing, activities, and infrastructure in 96 specialised adult congenital heart disease clinics in Europe","volume":"292","author":"Thomet","year":"2019","journal-title":"Int J Cardiol"},{"key":"2026100502565768400_ehag616-B123","doi-asserted-by":"publisher","DOI":"10.21470\/1678-9741-2023-0039","article-title":"Adult congenital heart disease: report from a public reference hospital in Northeastern Brazil","volume":"38","author":"Diogenes","year":"2023","journal-title":"Braz J Cardiovasc Surg"},{"key":"2026100502565768400_ehag616-B124","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1093\/eurheartj\/ehaa554","article-title":"2020 ESC guidelines for the management of adult congenital heart disease","volume":"42","author":"Baumgartner","year":"2021","journal-title":"Eur Heart J"},{"key":"2026100502565768400_ehag616-B125","doi-asserted-by":"publisher","first-page":"822","DOI":"10.1016\/j.jacc.2025.09.006","article-title":"2025 ACC\/AHA\/HRS\/ISACHD\/SCAI guideline for the management of adults with congenital heart disease: a report of the American College of Cardiology\/American Heart Association Joint Committee on clinical practice guidelines","volume":"87","author":"Gurvitz","year":"2026","journal-title":"J Am Coll Cardiol"},{"key":"2026100502565768400_ehag616-B126","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1177\/1460458212446761","article-title":"The use of personal digital assistants in clinical decision making by health care professionals: a systematic review","volume":"19","author":"Divall","year":"2013","journal-title":"Health Informatics J"},{"key":"2026100502565768400_ehag616-B127","first-page":"1","volume-title":"Frontiers of Statistics and Data Science","author":"Deliu","year":"2025"},{"key":"2026100502565768400_ehag616-B128","doi-asserted-by":"publisher","first-page":"1804","DOI":"10.1161\/CIRCULATIONAHA.113.005817","article-title":"Specialized adult congenital heart disease care: the impact of policy on mortality","volume":"129","author":"Mylotte","year":"2014","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B129","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1016\/j.jacc.2025.12.076","article-title":"The future of adult congenital heart care in the United States: are we keeping up with the pace of progress?","volume":"87","author":"Daniels","year":"2026","journal-title":"J Am Coll Cardiol"},{"key":"2026100502565768400_ehag616-B130","doi-asserted-by":"publisher","first-page":"e698","DOI":"10.1161\/CIR.0000000000000603","article-title":"2018 AHA\/ACC guideline for the management of adults with congenital heart disease: a report of the American College of Cardiology\/American Heart Association task force on clinical practice guidelines","volume":"139","author":"Stout","year":"2019","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B131","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/j.nima.2006.08.147","article-title":"TeleHealth networks: instant messaging and point-to-point communication over the internet","volume":"569","author":"Sachpazidis","year":"2006","journal-title":"Nucl Instrum Methods Phys Res A"},{"key":"2026100502565768400_ehag616-B132","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1093\/eurheartj\/ehp551","article-title":"Structure and activities of adult congenital heart disease programmes in Europe","volume":"31","author":"Moons","year":"2010","journal-title":"Eur Heart J"},{"key":"2026100502565768400_ehag616-B133","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.ejcnurse.2005.10.010","article-title":"Nurse specialists in adult congenital heart disease: the current status in Europe","volume":"5","author":"Moons","year":"2006","journal-title":"Eur J Cardiovasc Nurs"},{"key":"2026100502565768400_ehag616-B134","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1161\/cir.0000000000000352","article-title":"Chronic heart failure in congenital heart disease: a scientific statement from the American Heart Association","volume":"133","author":"Stout","year":"2016","journal-title":"Circulation"},{"key":"2026100502565768400_ehag616-B135","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph20105775","article-title":"Telemedicine in adult congenital heart disease: usefulness of digital health technology in the assistance of critical patients","volume":"20","author":"Borrelli","year":"2023","journal-title":"Int J Environ Res Public Health"},{"key":"2026100502565768400_ehag616-B136","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1016\/j.jaccas.2021.04.005","article-title":"Adult congenital heart disease telemedicine and future directions","volume":"3","author":"Kay","year":"2021","journal-title":"JACC Case Rep"},{"key":"2026100502565768400_ehag616-B137","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacadv.2022.100153","article-title":"Artificial intelligence in congenital heart disease: current state and prospects","volume":"1","author":"Jone","year":"2022","journal-title":"JACC Adv"},{"key":"2026100502565768400_ehag616-B138","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1055\/a-2154-6659","article-title":"The congenital cardiology cloud - optimizing long-term care by connecting ambulatory and hospital medical attendance via telemedicine","volume":"236","author":"Rottermann","year":"2024","journal-title":"Klin Padiatr"},{"key":"2026100502565768400_ehag616-B139","doi-asserted-by":"publisher","first-page":"2244","DOI":"10.1016\/j.jacc.2013.07.099","article-title":"Building quality indicators to improve care for adults with congenital heart disease","volume":"62","author":"Gurvitz","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"2026100502565768400_ehag616-B140","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1093\/ehjci\/jeac147","article-title":"A framework of deep learning networks provides expert-level accuracy for the detection and prognostication of pulmonary arterial hypertension","volume":"23","author":"Diller","year":"2022","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2026100502565768400_ehag616-B141","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1093\/eurheartj\/ehy915","article-title":"Machine learning algorithms estimating prognosis and guiding therapy in adult congenital heart disease: data from a single tertiary centre including 10 019 patients","volume":"40","author":"Diller","year":"2019","journal-title":"Eur Heart J"},{"key":"2026100502565768400_ehag616-B142","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacadv.2022.100017","article-title":"Deep learning in medicine","volume":"1","author":"Toma","year":"2022","journal-title":"JACC Adv"},{"key":"2026100502565768400_ehag616-B143","doi-asserted-by":"publisher","first-page":"3053","DOI":"10.1038\/s41591-024-03246-6","article-title":"The European health data space can be a boost for research beyond borders","volume":"30","author":"Ganna","year":"2024","journal-title":"Nat Med"},{"key":"2026100502565768400_ehag616-B144","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.mcpdig.2023.12.002","article-title":"Beyond atrial fibrillation: machine learning algorithm predicts stroke in adult patients with congenital heart disease","volume":"2","author":"Chiriac","year":"2024","journal-title":"Mayo Clin Proc Digit Health"},{"key":"2026100502565768400_ehag616-B145","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1093\/eurheartj\/ehae651","article-title":"Electrocardiogram-based deep learning to predict mortality in paediatric and adult congenital heart disease","volume":"46","author":"Mayourian","year":"2025","journal-title":"Eur Heart J"},{"key":"2026100502565768400_ehag616-B146","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1093\/eurheartj\/ehae085","article-title":"Early hybrid cardiac rehabilitation in congenital heart disease: the QUALIREHAB trial","volume":"45","author":"Amedro","year":"2024","journal-title":"Eur Heart J"},{"key":"2026100502565768400_ehag616-B147","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1007\/s00431-017-3081-y","article-title":"Children's experiences of congenital heart disease: a systematic review of qualitative studies","volume":"177","author":"Chong","year":"2018","journal-title":"Eur J Pediatr"},{"key":"2026100502565768400_ehag616-B148","doi-asserted-by":"publisher","first-page":"4200","DOI":"10.1093\/eurheartj\/ehaa614","article-title":"Recommendations for advance care planning in adults with congenital heart disease: a position paper from the ESC working group of adult congenital heart disease, the Association of Cardiovascular Nursing and Allied Professions (ACNAP), the European Association for Palliative Care (EAPC), and the International Society for Adult Congenital Heart Disease (ISACHD)","volume":"41","author":"Schwerzmann","year":"2020","journal-title":"Eur Heart J"},{"key":"2026100502565768400_ehag616-B149","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1111\/hex.13506","article-title":"Meaningful patient and public involvement in digital health innovation, implementation and evaluation: a systematic review","volume":"25","author":"Baines","year":"2022","journal-title":"Health Expect"}],"container-title":["European Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eurheartj\/advance-article-pdf\/doi\/10.1093\/eurheartj\/ehag616\/71589184\/ehag616.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurheartj\/advance-article-pdf\/doi\/10.1093\/eurheartj\/ehag616\/71589184\/ehag616.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T06:57:05Z","timestamp":1791183425000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurheartj\/advance-article\/doi\/10.1093\/eurheartj\/ehag616\/8862373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,5]]},"references-count":149,"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/ehag616","relation":{},"ISSN":["0195-668X","1522-9645"],"issn-type":[{"value":"0195-668X","type":"print"},{"value":"1522-9645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,5]]},"article-number":"ehag616"}}