{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T18:41:20Z","timestamp":1793644880990,"version":"4.5.1"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,1,1]]},"DOI":"10.1093\/eurheartj\/ehi002","type":"journal-article","created":{"date-parts":[[2004,11,23]],"date-time":"2004-11-23T22:14:09Z","timestamp":1101248049000},"page":"18-26","source":"Crossref","is-referenced-by-count":239,"title":["Mortality rates in patients with ST-elevation vs. non-ST-elevation acute myocardial infarction: observations from an unselected cohort"],"prefix":"10.1093","volume":"26","author":[{"given":"Christian Juhl","family":"Terkelsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens Flensted","family":"Lassen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bjarne Linde","family":"N\u00f8rgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens Christian","family":"Gerdes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tage","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liv Bj\u00f8rn-Hansen","family":"G\u00f8tzsche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torsten Toftegaard","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henning Rud","family":"Andersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2004,11,23]]},"reference":[{"key":"key\n\t\t\t\t20171012000802_EHI002C1","doi-asserted-by":"crossref","unstructured":"Van de Werf F, Ardissino D, Betriu A, Cokkinos DV, Falk E, Fox KA, Julian D, Lengyel M, Neumann FJ, Ruzyllo W, Thygesen C, Underwood SR, Vahanian A, Verheugt FW, Wijns W. Management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J2003;24:28\u201366.","DOI":"10.1016\/S0195-668X(02)00618-8"},{"key":"key\n\t\t\t\t20171012000802_EHI002C2","doi-asserted-by":"crossref","unstructured":"Braunwald E, Antman EM, Beasley JW, Califf RM, Cheitlin MD, Hochman JS, Jones RH, Kereiakes D, Kupersmith J, Levin TN, Pepine CJ, Schaeffer JW, Smith EE 3rd, Steward DE, Theroux P, Gibbons RJ, Alpert JS, Faxon DP, Fuster V, Gregoratos G, Hiratzka LF, Jacobs AK, Smith SC Jr. ACC\/AHA guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction\u20142002: summary article: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients with Unstable Angina). Circulation2002;106:1893\u20131900.","DOI":"10.1161\/01.CIR.0000037106.76139.53"},{"key":"key\n\t\t\t\t20171012000802_EHI002C3","doi-asserted-by":"crossref","unstructured":"Braunwald E. Application of current guidelines to the management of unstable angina and non-ST-elevation myocardial infarction. Circulation2003;108:28111\u201328137.","DOI":"10.1161\/01.CIR.0000086952.14979.32"},{"key":"key\n\t\t\t\t20171012000802_EHI002C4","doi-asserted-by":"crossref","unstructured":"Boersma E, Maas AC, Deckers JW, Simoons ML. Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour. Lancet1996;348:771\u2013775.","DOI":"10.1016\/S0140-6736(96)02514-7"},{"key":"key\n\t\t\t\t20171012000802_EHI002C5","doi-asserted-by":"crossref","unstructured":"Fibrinolytic Therapy Trialists' (FTT) Collaborative Group. Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and morbidity results from all randomised trials of more than 1000 patients. Lancet1994;343:311\u2013322.","DOI":"10.1016\/S0140-6736(94)91161-4"},{"key":"key\n\t\t\t\t20171012000802_EHI002C6","doi-asserted-by":"crossref","unstructured":"Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet2003;361:13\u201320.","DOI":"10.1016\/S0140-6736(03)12113-7"},{"key":"key\n\t\t\t\t20171012000802_EHI002C7","doi-asserted-by":"crossref","unstructured":"Eagle KA, Goodman SG, Avezum A, Budaj A, Sullivan CM, Lopez-Sendon J. Practice variation and missed opportunities for reperfusion in ST-segment-elevation myocardial infarction: findings from the Global Registry of Acute Coronary Events (GRACE). Lancet2002;359:373\u2013377.","DOI":"10.1016\/S0140-6736(02)07595-5"},{"key":"key\n\t\t\t\t20171012000802_EHI002C8","doi-asserted-by":"crossref","unstructured":"Hasdai D, Behar S, Wallentin L, Danchin N, Gitt AK, Boersma E, Fioretti PM, Simoons ML, Battler A. A prospective survey of the characteristics, treatments and outcomes of patients with acute coronary syndromes in Europe and the Mediterranean basin. The Euro Heart Survey of Acute Coronary Syndromes (Euro Heart Survey ACS). Eur Heart J2002;23:1190\u20131201.","DOI":"10.1053\/euhj.2002.3193"},{"key":"key\n\t\t\t\t20171012000802_EHI002C9","doi-asserted-by":"crossref","unstructured":"Rogers WJ, Canto JG, Lambrew CT, Tiefenbrunn AJ, Kinkaid B, Shoultz DA, Frederick PD, Every N. Temporal trends in the treatment of over 1.5 million patients with myocardial infarction in the US from 1990 through 1999: the National Registry of Myocardial Infarction 1, 2 and 3. J Am Coll Cardiol2000;36:2056\u20132063.","DOI":"10.1016\/S0735-1097(00)00996-7"},{"key":"key\n\t\t\t\t20171012000802_EHI002C10","doi-asserted-by":"crossref","unstructured":"The Joint European Society of Cardiology\/American College of Cardiology Committee. Myocardial infarction redefined\u2014a consensus document of The Joint European Society of Cardiology\/American College of Cardiology Committee for the Redifinition of Myocardial Infarction. Eur Heart J2000;21:1502\u20131513.","DOI":"10.1053\/euhj.2000.2305"},{"key":"key\n\t\t\t\t20171012000802_EHI002C11","doi-asserted-by":"crossref","unstructured":"Grambsch PM, Therneau TM. Proportional hazards tests and diagnostics based on weighted residuals. Biometrika1994;81:515\u2013526.","DOI":"10.1093\/biomet\/81.3.515"},{"key":"key\n\t\t\t\t20171012000802_EHI002C12","doi-asserted-by":"crossref","unstructured":"Schemper M, Smith TL. Efficient evaluation of treatment effects in the presence of missing covariate values. Stat Med1990;9:777\u2013784.","DOI":"10.1002\/sim.4780090707"},{"key":"key\n\t\t\t\t20171012000802_EHI002C13","doi-asserted-by":"crossref","unstructured":"Schemper M, Heinze G. Revisited for prognostic factor studies. Stat Med1997;16:73\u201380.","DOI":"10.1002\/(SICI)1097-0258(19970115)16:1<73::AID-SIM472>3.0.CO;2-Z"},{"key":"key\n\t\t\t\t20171012000802_EHI002C14","doi-asserted-by":"crossref","unstructured":"Simon R, Altman DG. Statistical aspects of prognostic factor studies in oncology. Br J Cancer1994;69:979\u2013985.","DOI":"10.1038\/bjc.1994.192"},{"key":"key\n\t\t\t\t20171012000802_EHI002C15","doi-asserted-by":"crossref","unstructured":"Goldberg RJ, Currie K, White K, Brieger D, Steg PG, Goodman SG, Dabbous O, Fox KA, Gore JM. Six-month outcomes in a multinational registry of patients hospitalized with an acute coronary syndrome (The Global Registry of Acute Coronary Events [GRACE]). Am J Cardiol2004;93:288\u2013293.","DOI":"10.1016\/j.amjcard.2003.10.006"},{"key":"key\n\t\t\t\t20171012000802_EHI002C16","doi-asserted-by":"crossref","unstructured":"Goldberg RJ, Steg PG, Sadiq I, Granger CB, Jackson EA, Budaj A, Brieger D, Avezum A, Goodman S. Extent of, and factors associated with, delay to hospital presentation in patients with acute coronary disease (the GRACE registry). Am J Cardiol2002;89:791\u2013796.","DOI":"10.1016\/S0002-9149(02)02186-0"},{"key":"key\n\t\t\t\t20171012000802_EHI002C17","doi-asserted-by":"crossref","unstructured":"Granger CB, Goldberg RJ, Dabbous O, Pieper KS, Eagle KA, Cannon CP, Van de Werf F, Avezum A, Goodman SG, Flather MD, Fox KAA, for the Global Registry of Acute Registry of Acute Coronary Events Investigators. Predictors of hospital mortality in the global registry of acute coronary events. Arch Intern Med2003;163:2345\u20132353.","DOI":"10.1001\/archinte.163.19.2345"},{"key":"key\n\t\t\t\t20171012000802_EHI002C18","doi-asserted-by":"crossref","unstructured":"Armstrong PW. Coronary reperfusion: numerators searching for denominators. Lancet2002;359:371\u2013372.","DOI":"10.1016\/S0140-6736(02)07588-8"},{"key":"key\n\t\t\t\t20171012000802_EHI002C19","doi-asserted-by":"crossref","unstructured":"Steg PG, Goldberg RJ, Gore JM, Fox KA, Eagle KA, Flather MD, Sadiq I, Kasper R, Rushton-Mellor SK, Anderson FA. Baseline characteristics, management practices, and in-hospital outcomes of patients hospitalized with acute coronary syndromes in the Global Registry of Acute Coronary Events (GRACE). Am J Cardiol2002;90:358\u2013363.","DOI":"10.1016\/S0002-9149(02)02489-X"},{"key":"key\n\t\t\t\t20171012000802_EHI002C20","doi-asserted-by":"crossref","unstructured":"Andersen HR, Nielsen TT, Rasmussen K, Thuesen L, Kelbaek H, Thayssen P, Abildgaard U, Pedersen F, Madsen JK, Grande P, Villadsen AB, Krusell LR, Haghfelt T, Lomholt P, Husted SE, Vigholt E, Kjaergard HK, Mortensen LS. A Comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction. N Engl J Med2003;349:733\u2013742.","DOI":"10.1056\/NEJMoa025142"},{"key":"key\n\t\t\t\t20171012000802_EHI002C21","doi-asserted-by":"crossref","unstructured":"The GUSTO V Investigators. Reperfusion therapy for acute myocardial infarction with fibrinolytic therapy or combination reduced fibrinolytic therapy and platelet glycoprotein IIb\/IIIa inhibition: the GUSTO V randomised trial. Lancet2001;357:1905\u20131914.","DOI":"10.1016\/S0140-6736(00)05059-5"},{"key":"key\n\t\t\t\t20171012000802_EHI002C22","doi-asserted-by":"crossref","unstructured":"Assessment of the Safety and Efficacy of a New Thrombolytic (ASSENT-2) Investigators. Single-bolus tenecteplase compared with front-loaded alteplase in acute myocardial infarction: the ASSENT-2 double blind randomised trial. Lancet1999;354:716\u2013722.","DOI":"10.1016\/S0140-6736(99)07403-6"},{"key":"key\n\t\t\t\t20171012000802_EHI002C23","doi-asserted-by":"crossref","unstructured":"Sinnaeve P, Alexander J, Belmans A, Bogaerts K, Langer A, Diaz R, Ardissino D, Vahanian A, Pehrsson K, Armstrong P, Van de Werf F. One-year follow-up of the ASSENT-2 trial: a double-blind, randomized comparison of single-bolus tenecteplase and front-loaded alteplase in 16,949 patients with ST-elevation acute myocardial infarction. Am Heart J2003;146:27\u201332.","DOI":"10.1016\/S0002-8703(03)00117-0"},{"key":"key\n\t\t\t\t20171012000802_EHI002C24","doi-asserted-by":"crossref","unstructured":"Lincoff AM, Califf RM, Van de WF, Willerson JT, White HD, Armstrong PW, Guetta V, Gibler WB, Hochman JS, Bode C, Vahanian A, Steg PG, Ardissino D, Savonitto S, Bar F, Sadowski Z, Betriu A, Booth JE, Wolski K, Waller M, Topol EJ. Mortality at 1 year with combination platelet glycoprotein IIb\/IIIa inhibition and reduced-dose fibrinolytic therapy vs conventional fibrinolytic therapy for acute myocardial infarction: GUSTO V randomized trial. JAMA2002;288:2130\u20132135.","DOI":"10.1001\/jama.288.17.2130"},{"key":"key\n\t\t\t\t20171012000802_EHI002C25","doi-asserted-by":"crossref","unstructured":"Brown N, Melville M, Gray D, Young T, Skene AM, Wilcox RG, Hampton JR. Relevance of clinical trial results in myocardial infarction to medical practice: comparison of four year outcome in participants of a thrombolytic trial, patients receiving routine thrombolysis, and those deemed ineligible for thrombolysis. Heart1999;81:598\u2013602.","DOI":"10.1136\/hrt.81.6.598"},{"key":"key\n\t\t\t\t20171012000802_EHI002C26","doi-asserted-by":"crossref","unstructured":"Bahit MC, Cannon CP, Antman EM, Murphy SA, Gibson CM, McCabe CH, Braunwald E. Direct comparison of characteristics, treatment, and outcomes of patients enrolled versus patients not enrolled in a clinical trial at centers participating in the TIMI 9 Trial and TIMI 9 Registry. Am Heart J2003;145:109\u2013117.","DOI":"10.1067\/mhj.2003.43"},{"key":"key\n\t\t\t\t20171012000802_EHI002C27","doi-asserted-by":"crossref","unstructured":"Wallentin L, Lagerqvist B, Husted S, Kontny F, Stahle E, Swahn E. Outcome at 1 year after an invasive compared with a non-invasive strategy in unstable coronary-artery disease: the FRISC II invasive randomised trial. FRISC II investigators. Fast revascularisation during instability in coronary artery disease. Lancet2000;356:9\u201316.","DOI":"10.1016\/S0140-6736(00)02427-2"},{"key":"key\n\t\t\t\t20171012000802_EHI002C28","doi-asserted-by":"crossref","unstructured":"Pell JP, Simpson E, Rodger JC, Finlayson A, Clark D, Anderson J, Pell AC. Impact of changing diagnostic criteria on incidence, management, and outcome of acute myocardial infarction: retrospective cohort study. Br Med J2003;326:134\u2013135.","DOI":"10.1136\/bmj.326.7381.134"},{"key":"key\n\t\t\t\t20171012000802_EHI002C29","doi-asserted-by":"crossref","unstructured":"Go AS, Barron HV, Rundle AC, Ornato JP, Avins AL. Bundle-branch block and in-hospital mortality in acute myocardial infarction. Ann Intern Med1998;129:690\u2013697.","DOI":"10.7326\/0003-4819-129-9-199811010-00003"},{"key":"key\n\t\t\t\t20171012000802_EHI002C30","doi-asserted-by":"crossref","unstructured":"Sgarbossa EB, Pinski SL, Topol EJ, Califf RM, Barbagelata A, Goodman SG, Gates KB, Granger CB, Miller DP, Underwood DA, Wagner GS. Acute myocardial infarction and complete bundle branch block at hospital admission: clinical characteristics and outcome in the thrombolytic era. J Am Coll Cardiol1998;31:105\u2013110.","DOI":"10.1016\/S0735-1097(97)00446-4"},{"key":"key\n\t\t\t\t20171012000802_EHI002C31","doi-asserted-by":"crossref","unstructured":"Jha P, Deboer D, Sykora K, Naylor CD. Characteristics and mortality outcomes of thrombolysis trial participants and nonparticipants: a population-based comparison. J Am Coll Cardiol1996;27:1335\u20131342.","DOI":"10.1016\/0735-1097(96)00018-6"},{"key":"key\n\t\t\t\t20171012000802_EHI002C32","doi-asserted-by":"crossref","unstructured":"Holmes DR, Jr, Berger PB, Hochman JS, Granger CB, Thompson TD, Califf RM, Vahanian A, Bates ER, Topol EJ. Cardiogenic shock in patients with acute ischemic syndromes with and without ST-segment elevation. Circulation1999;100:2067\u20132073.","DOI":"10.1161\/01.CIR.100.20.2067"},{"key":"key\n\t\t\t\t20171012000802_EHI002C33","doi-asserted-by":"crossref","unstructured":"Neskovic A, Otasevic P, Bojic M, Popovic AD. Association of Killip class on admission and left ventricular dilatation after myocardial infarction: a closer look into an old clinical classification. Am Heart J1999;137:361\u2013367.","DOI":"10.1053\/hj.1999.v137.89744"}],"container-title":["European Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/eurheartj\/article-pdf\/26\/1\/18\/5941487\/ehi002.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,4]],"date-time":"2020-04-04T04:06:17Z","timestamp":1585973177000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/eurheartj\/article\/26\/1\/18\/494614\/Mortality-rates-in-patients-with-STelevation-vs"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,11,23]]},"references-count":33,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2004,11,23]]},"published-print":{"date-parts":[[2005,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/ehi002","relation":{},"ISSN":["1522-9645","0195-668X"],"issn-type":[{"value":"1522-9645","type":"electronic"},{"value":"0195-668X","type":"print"}],"subject":[],"published-other":{"date-parts":[[2005,1]]},"published":{"date-parts":[[2004,11,23]]}}}