{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T23:05:50Z","timestamp":1787785550635,"version":"build-2784847793"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,4,1]]},"DOI":"10.1093\/eurheartj\/ehi773","type":"journal-article","created":{"date-parts":[[2006,2,9]],"date-time":"2006-02-09T01:16:23Z","timestamp":1139447783000},"page":"861-866","source":"Crossref","is-referenced-by-count":108,"title":["B-type natriuretic peptide in paediatric patients with congenital heart disease"],"prefix":"10.1093","volume":"27","author":[{"given":"Andreas","family":"Koch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Zink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Singer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2006,2,8]]},"reference":[{"key":"key\n\t\t\t\t20171012002036_EHI773C1","doi-asserted-by":"crossref","unstructured":"Levin ER, Gardner DG, Samson WK. Natriuretic peptides. N Engl J Med1998;339:321\u2013328.","DOI":"10.1056\/NEJM199807303390507"},{"key":"key\n\t\t\t\t20171012002036_EHI773C2","doi-asserted-by":"crossref","unstructured":"Cowie MR, Mendez GF. BNP and congestive heart failure. Prog Cardiovasc Dis2002;44:293\u2013321.","DOI":"10.1053\/pcad.2002.24599"},{"key":"key\n\t\t\t\t20171012002036_EHI773C3","doi-asserted-by":"crossref","unstructured":"Maisel AS, Krishnaswamy P, Nowak RM, McCord J, Hollander JE, Duc P, Omland T, Storrow AB, Abraham WT, Wu AHB, Clopton P, Steg PG, Westheim A, Knudsen CW, Perez A, Kazanegra R, Herrmann HC, McCullough PA. Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure. N Engl J Med2002;347:161\u2013167.","DOI":"10.1056\/NEJMoa020233"},{"key":"key\n\t\t\t\t20171012002036_EHI773C4","doi-asserted-by":"crossref","unstructured":"Nakamura T, Sakamoto K, Yamano T, Kikkawa M, Zen K, Hikosaka T, Kubota T, Azuma A, Nishimura T. Increased plasma brain natriuretic peptide levels as a guide for silent myocardial ischemia in patients with non-obstructive hypertrophic cardiomyopathy. J Am Coll Cardiol2002;39:1657\u20131663.","DOI":"10.1016\/S0735-1097(02)01813-2"},{"key":"key\n\t\t\t\t20171012002036_EHI773C5","doi-asserted-by":"crossref","unstructured":"Crilley JG, Farrer M. Left ventricular remodelling and brain natriuretic peptide after the first myocardial infarction. Heart2001;86:638\u2013642.","DOI":"10.1136\/heart.86.6.638"},{"key":"key\n\t\t\t\t20171012002036_EHI773C6","doi-asserted-by":"crossref","unstructured":"Matsuo K, Nishikimi T, Yutani C, Kurita T, Shimizu W, Taguchi A, Suyama K, Aihara N, Kamakura S, Kangawa K, Takamiya M, Shimomura K. Diagnostic value of plasma levels of brain natriuretic peptide in arrhythmogenic right ventricular dysplasia. Circulation1998;98:2433\u20132440.","DOI":"10.1161\/01.CIR.98.22.2433"},{"key":"key\n\t\t\t\t20171012002036_EHI773C7","doi-asserted-by":"crossref","unstructured":"Bolger AP, Sharma R, Li W, Leenarts M, Kalra PR, Kemp M, Coats AJS, Anker SD, Gatzoulis MA. Neurohumoral activation and the congenital heart failure syndrome in adults with congenital heart disease. Circulation2002;106:92\u201399.","DOI":"10.1161\/01.CIR.0000020009.30736.3F"},{"key":"key\n\t\t\t\t20171012002036_EHI773C8","doi-asserted-by":"crossref","unstructured":"Book WM, Hott BJ, McConnel M. B-type natriuretic peptide levels in adults with congenital heart disease and right ventricular failure. Am J Cardiol2005;95:545\u2013546.","DOI":"10.1016\/j.amjcard.2004.10.031"},{"key":"key\n\t\t\t\t20171012002036_EHI773C9","doi-asserted-by":"crossref","unstructured":"Tulevski II, Groenink M, van der Wall EE, van Veldhuisen DJ, Boomsma F, Stoker J, Hirsch A, Lemkes JS, Mulder BJM. Increased brain and atrial natriuretic peptides in patients with chronic right ventricular pressure overload: correlation between plasma neurohormones and right ventricular dysfunction. Heart2001;86:27\u201330.","DOI":"10.1136\/heart.86.1.27"},{"key":"key\n\t\t\t\t20171012002036_EHI773C10","doi-asserted-by":"crossref","unstructured":"Law YM, Keller BB, Feingold BM, Boyle GJ. Usefulness of plasma B-type natriuretic peptide to identify ventricular dysfunction in pediatric and adult patients with congenital heart disease. Am J Cardiol2005;95:474\u2013478.","DOI":"10.1016\/j.amjcard.2004.10.014"},{"key":"key\n\t\t\t\t20171012002036_EHI773C11","doi-asserted-by":"crossref","unstructured":"Westerlind A, Wahlander H, Lindstedt G, Lundberg PA, Holmgren D. Clinical signs of heart failure are associated with increased levels of natriuretic peptide types B and A in children with congenital heart defects or cardiomyopathy. Acta Paediatr2004;93:340\u2013345.","DOI":"10.1111\/j.1651-2227.2004.tb02958.x"},{"key":"key\n\t\t\t\t20171012002036_EHI773C12","doi-asserted-by":"crossref","unstructured":"Nir A, Bar-Oz B, Perles Z, Korach A, Rein AJJT. N-terminal pro-B-type natriuretic peptide: reference plasma levels from birth to adolescence. Elevated levels at birth and in infants and children with heart diseases. Acta Paediatr2004;93:603\u2013607.","DOI":"10.1111\/j.1651-2227.2004.tb02984.x"},{"key":"key\n\t\t\t\t20171012002036_EHI773C13","doi-asserted-by":"crossref","unstructured":"Mir TS, Marohn S, Laer S, Eiselt M, Grollmus O, Weil J. Plasma concentrations of N-terminal pro-brain natriuretic peptide in control children from the neonatal to adolescent period and in children with congestive heart failure. Pediatrics2002;110:e76.","DOI":"10.1542\/peds.110.6.e76"},{"key":"key\n\t\t\t\t20171012002036_EHI773C14","doi-asserted-by":"crossref","unstructured":"Cowley CG, Bradley JD, Shaddy RE. B-type natriuretic peptide levels in congenital heart disease. Pediatr Cardiol2004;25:336\u2013340.","DOI":"10.1007\/s00246-003-0461-z"},{"key":"key\n\t\t\t\t20171012002036_EHI773C15","doi-asserted-by":"crossref","unstructured":"Suda K, Matsumura M, Matsumoto M. Clinical implication of plasma natriuretic peptides in children with ventricular septal defect. Pediatr Int2003;45:249\u2013254.","DOI":"10.1046\/j.1442-200X.2003.01716.x"},{"key":"key\n\t\t\t\t20171012002036_EHI773C16","doi-asserted-by":"crossref","unstructured":"Koch A, Singer H. Normal values of B-type natriuretic peptide in infants, children, and adolescents. Heart2003;89:875\u2013878.","DOI":"10.1136\/heart.89.8.875"},{"key":"key\n\t\t\t\t20171012002036_EHI773C17","doi-asserted-by":"crossref","unstructured":"Rauh M, Koch A. Plasma N-terminal pro B-type natriuretic peptide concentrations in a control population of infants and children. Clin Chem2003;49:1563\u20131564.","DOI":"10.1373\/49.9.1563"},{"key":"key\n\t\t\t\t20171012002036_EHI773C18","doi-asserted-by":"crossref","unstructured":"Schwachtgen L, Herrmann M, Georg T, Schwarz P, Marx N, Lindinger A. Reference values of NT-proBNP serum concentrations in the umbilical cord blood and in healthy neonates and children. Z Kardiol2005;94:399\u2013404.","DOI":"10.1007\/s00392-005-0246-x"},{"key":"key\n\t\t\t\t20171012002036_EHI773C19","doi-asserted-by":"crossref","unstructured":"Wang TJ, Larson MG, Levy D, Leip EP, Benjamin EJ, Wilson PW, Sutherland P, Omland T, Vasan RS. Impact of age and sex on plasma natriuretic peptide levels in healthy adults. Am J Cardiol2002;90:254\u2013258.","DOI":"10.1016\/S0002-9149(02)02464-5"},{"key":"key\n\t\t\t\t20171012002036_EHI773C20","doi-asserted-by":"crossref","unstructured":"Ikeda T, Matsuda K, Ito H, Shirakami G, Miyamato Y, Yoshimasa K, Nakao K, Ban T. Plasma levels of brain and atrial natriuretic peptides elevated in proportion to left ventricular end-systolic wall stress in patients with aortic stenosis. Am Heart J1997;133:307\u2013314.","DOI":"10.1016\/S0002-8703(97)70225-4"},{"key":"key\n\t\t\t\t20171012002036_EHI773C21","doi-asserted-by":"crossref","unstructured":"Qi W, Mathisen P, Kjekshus J, Simonsen S, Bjornerheim R, Endresen K, Hall C. Natriuretic peptides in patients with aortic stenosis. Am Heart J2001;142:725\u2013732.","DOI":"10.1067\/mhj.2001.117131"},{"key":"key\n\t\t\t\t20171012002036_EHI773C22","doi-asserted-by":"crossref","unstructured":"Gerber IL, Stewart RA, Legget ME, West TM, French RL, Sutton TM, Yandle TG, French JK, Richards AM, White HD. Increased plasma natriuretic peptide levels reflect symptom onset in aortic stenosis. Circulation2003;107:1884\u20131890.","DOI":"10.1161\/01.CIR.0000060533.79248.0C"},{"key":"key\n\t\t\t\t20171012002036_EHI773C23","unstructured":"Weber M, Arnold R, Rau M, Maikowski C, Keil E, Mitrovic V, Brandt R, Hamm C. N-terminal pro braintype natriuretic peptide (NT-proBNP) is a highly sensitive biochemical marker for surgical therapy in patients with aortic stenosis. Circulation2003;108(Suppl. 17):IV513."},{"key":"key\n\t\t\t\t20171012002036_EHI773C24","doi-asserted-by":"crossref","unstructured":"Prasad N, Bridges AB, Lang CC, Clarkson PBM, MacLeod C, Pringle TH, Struthers AD, MacDonald TM. Brain natriuretic peptide concentrations in patients with aortic stenosis. Am Heart J1997;133:477\u2013479.","DOI":"10.1016\/S0002-8703(97)70196-0"},{"key":"key\n\t\t\t\t20171012002036_EHI773C25","doi-asserted-by":"crossref","unstructured":"Talwar S, Downie PF, Squire IB, Davies JE, Barnett DB, Ng LL. Plasma N-terminal proBNP and cardiotrophin-1 are elevated in aortic stenosis. Eur J Heart Fail2001;3:15\u201319.","DOI":"10.1016\/S1388-9842(00)00074-X"},{"key":"key\n\t\t\t\t20171012002036_EHI773C26","doi-asserted-by":"crossref","unstructured":"Koch A, Singer H. Plasma levels of B-type natriuretic peptide in children and adolescents with aortic valve stenosis. Eur Heart J2005;doi:10.1093\/eurheartj\/ehi369.","DOI":"10.1093\/eurheartj\/ehi369"},{"key":"key\n\t\t\t\t20171012002036_EHI773C27","doi-asserted-by":"crossref","unstructured":"Mir TS, Falkenberg J, Friedrich B, Gottschalk U, Le TP, Laer S, Weil J. Levels of brain natriuretic peptide in children with right ventricular overload due to congenital cardiac disease. Cardiol Young2005;15:396\u2013401.","DOI":"10.1017\/S1047951105000831"},{"key":"key\n\t\t\t\t20171012002036_EHI773C28","doi-asserted-by":"crossref","unstructured":"Rosenkranz AC, Woods RL, Dusting GJ, Ritchie RH. Antihypertrophic actions of the natriuretic peptides in adult rat cardiomyocytes: importance of cyclic GMP. Cardiovasc Res2003;57:515\u2013522.","DOI":"10.1016\/S0008-6363(02)00667-3"},{"key":"key\n\t\t\t\t20171012002036_EHI773C29","doi-asserted-by":"crossref","unstructured":"Almeida SS, Azevedo A, Castro A, Frioes F, Freitas J, Ferreira A, Bettencourt P. B-type natriuretic peptide is related to left ventricular mass in hypertensive patients but not in athletes. Cardiology2002;98:113\u2013115.","DOI":"10.1159\/000066319"},{"key":"key\n\t\t\t\t20171012002036_EHI773C30","doi-asserted-by":"crossref","unstructured":"Yamamoto K, Burnett JC Jr, Jougasaki M, Nishimura RA, Bailey KR, Saito Y, Nakao K, Redfield MM. Superiority of brain natriuretic peptide as a hormonal marker of ventricular systolic and diastolic dysfunction and ventricular hypertrophy. Hypertension1996;28:988\u2013994.","DOI":"10.1161\/01.HYP.28.6.988"},{"key":"key\n\t\t\t\t20171012002036_EHI773C31","doi-asserted-by":"crossref","unstructured":"Pluim BM, Chin JC, De Roos A, Doornbos J, Siebelink HM, Van der Laarse A, Vliegen HW, Lamerichs RM, Bruschke AV, Van der Wall EE. Cardiac anatomy, function and metabolism in elite cyclists assessed by magnetic resonance imaging and spectroscopy. Eur Heart J1996;17:1271\u20131278.","DOI":"10.1093\/oxfordjournals.eurheartj.a015046"},{"key":"key\n\t\t\t\t20171012002036_EHI773C32","doi-asserted-by":"crossref","unstructured":"Hjortdal VE, Stenbog EV, Ravn HB, Emmertsen K, Jensen KT, Pedersen EB, Olsen KH, Hansen OK, Sorensen KE. Neurohormonal activation late after cavopulmonary connection. Heart2000;83:439\u2013443.","DOI":"10.1136\/heart.83.4.439"},{"key":"key\n\t\t\t\t20171012002036_EHI773C33","doi-asserted-by":"crossref","unstructured":"Knowles JW, Esposito G, Mao L, Hagaman JR, Fox JE, Smithies O, Rockman HA, Maeda N. Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice. J Clin Invest2001;107:975\u2013984.","DOI":"10.1172\/JCI11273"},{"key":"key\n\t\t\t\t20171012002036_EHI773C34","doi-asserted-by":"crossref","unstructured":"Cao L, Gardner D. Natriuretic peptides inhibit DNA synthesis in cardiac fibroblasts. Hypertension1995;25:227\u2013234.","DOI":"10.1161\/01.HYP.25.2.227"},{"key":"key\n\t\t\t\t20171012002036_EHI773C35","doi-asserted-by":"crossref","unstructured":"Tamura N, Ogawa Y, Chusho H, Nakamura K, Nakao K, Suda M, Kasahara M, Hashimoto R, Katsuura G, Mukoyama M, Itoh H, Saito Y, Tanaka I, Otani H, Katsuki M, Nakao K. Cardiac fibrosis in mice lacking brain natriuretic peptide. Proc Natl Acad Sci USA2000;97:4239\u20134244.","DOI":"10.1073\/pnas.070371497"},{"key":"key\n\t\t\t\t20171012002036_EHI773C36","doi-asserted-by":"crossref","unstructured":"D'Souza SP, Yellon DM, Martin C, Schulz R, Heusch G, Onady A, Ferdinandy P, Baxter GF. B-type natriuretic peptide (BNP) limits infarct size in rat isolated heart via K-ATP channel opening. Am J Physiol Heart Circ Physiol2003;284:H1592\u2013H1600.","DOI":"10.1152\/ajpheart.00902.2002"},{"key":"key\n\t\t\t\t20171012002036_EHI773C37","doi-asserted-by":"crossref","unstructured":"Hama N, Itoh H, Shirakami G, Nakagawa O, Suga S, Ogawa Y, Masuda I, Nakanishi K, Yoshimasa T, Hashimoto Y, Yamaguchi M, Hori R, Yasue H, Nakao K. Rapid ventricular induction of brain natriuretic peptide gene expression in experimental acute myocardial infarction. Circulation1995;92:1558\u20131564.","DOI":"10.1161\/01.CIR.92.6.1558"},{"key":"key\n\t\t\t\t20171012002036_EHI773C38","doi-asserted-by":"crossref","unstructured":"Talwar S, Squire IB, Downie PF, Davies JE, Ng LL. Plasma N terminal pro-brain natriuretic peptide and cardiotrophin 1 are raised in unstable angina. Heart2000;84:421\u2013424.","DOI":"10.1136\/heart.84.4.421"},{"key":"key\n\t\t\t\t20171012002036_EHI773C39","doi-asserted-by":"crossref","unstructured":"D'Souza SP, Baxter GF. B-type natriuretic peptide: a good omen in myocardial ischemia. Heart2003;89:707\u2013709.","DOI":"10.1136\/heart.89.7.707"},{"key":"key\n\t\t\t\t20171012002036_EHI773C40","doi-asserted-by":"crossref","unstructured":"Jefferies JL, Chang AC. The neurohormonal axis and biochemical markers of heart failure. Cardiol Young2005;15:333\u2013344.","DOI":"10.1017\/S1047951105000740"}],"container-title":["European Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/eurheartj\/article-pdf\/27\/7\/861\/9626238\/ehi773.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,10,12]],"date-time":"2017-10-12T04:23:23Z","timestamp":1507782203000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/eurheartj\/article\/27\/7\/861\/2887154\/Btype-natriuretic-peptide-in-paediatric-patients"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2,8]]},"references-count":40,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2006,2,8]]},"published-print":{"date-parts":[[2006,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/ehi773","relation":{},"ISSN":["1522-9645","0195-668X"],"issn-type":[{"value":"1522-9645","type":"electronic"},{"value":"0195-668X","type":"print"}],"subject":[],"published-other":{"date-parts":[[2006,4]]},"published":{"date-parts":[[2006,2,8]]}}}