{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T13:35:04Z","timestamp":1784640904494,"version":"3.55.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1093\/eurheartj\/ehp314","type":"journal-article","created":{"date-parts":[[2009,8,18]],"date-time":"2009-08-18T01:32:02Z","timestamp":1250559122000},"page":"2888-2896","source":"Crossref","is-referenced-by-count":44,"title":["Diagnosing vasovagal syncope based on quantitative history-taking: validation of the Calgary Syncope Symptom Score"],"prefix":"10.1093","volume":"30","author":[{"given":"Jacobus J.C.M.","family":"Romme","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nynke","family":"van Dijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly R.","family":"Boer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick M.M.","family":"Bossuyt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wouter","family":"Wieling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes B.","family":"Reitsma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2009,8,17]]},"reference":[{"key":"key\n\t\t\t\t20170626100734_EHP314C1","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.eupc.2004.08.008","article-title":"Guidelines on management (diagnosis and treatment) of syncope\u2013update 2004","volume":"6","author":"Brignole","year":"2004","journal-title":"Europace"},{"key":"key\n\t\t\t\t20170626100734_EHP314C2","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s10286-004-1002-4","article-title":"Defining and classifying syncope","volume":"14","author":"Thijs","year":"2004","journal-title":"Clin Auton Res"},{"key":"key\n\t\t\t\t20170626100734_EHP314C3","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1056\/NEJMoa012407","article-title":"Incidence and prognosis of syncope","volume":"12","author":"Soteriades","year":"2002","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170626100734_EHP314C4","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s10286-004-1006-0","article-title":"Diagnostic value of history taking in reflex syncope","volume":"14","author":"Colman","year":"2004","journal-title":"Clin Auton Res"},{"key":"key\n\t\t\t\t20170626100734_EHP314C5","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1093\/eurheartj\/ehi663","article-title":"Evidence-based common sense: the role of clinical history for the diagnosis of vasovagal syncope","volume":"3","author":"Morillo","year":"2006","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20170626100734_EHP314C6","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1056\/NEJM200012213432507","article-title":"Syncope","volume":"25","author":"Kapoor","year":"2000","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170626100734_EHP314C7","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1002\/9780470692639.ch9","article-title":"Neurally-mediated reflex syncope: recognition by history and clinical testing","volume-title":"Syncope and Transient Loss of Consciousness: Multidisciplinary Management","author":"Serletis","year":"2007"},{"key":"key\n\t\t\t\t20170626100734_EHP314C8","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1093\/eurheartj\/ehi584","article-title":"Diagnostic criteria for vasovagal syncope based on a quantitative history","volume":"3","author":"Sheldon","year":"2006","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20170626100734_EHP314C9","first-page":"1186","article-title":"The Second Prevention of Syncope Trial (POST II)\u2014a randomized clinical trial of fludrocortisone for the prevention of neurally mediated syncope: rationale and study design","volume":"6","author":"Raj","year":"2006","journal-title":"Am Heart J"},{"key":"key\n\t\t\t\t20170626100734_EHP314C10","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1540-8167.2007.00984.x","article-title":"High diagnostic yield and accuracy of history, physical examination, and ECG in patients with transient loss of consciousness in FAST: the Fainting Assessment study","volume":"1","author":"Van Dijk","year":"2008","journal-title":"J Cardiovasc Electrophysiol"},{"key":"key\n\t\t\t\t20170626100734_EHP314C11","first-page":"264","volume":"3\u20134","author":"Declaration of Helsinki","year":"1991","journal-title":"Law Med Health Care"},{"key":"key\n\t\t\t\t20170626100734_EHP314C12","first-page":"184","article-title":"Conditions that mimic syncope","volume-title":"The Evaluation and Treatment of Syncope: A Handbook for Clinical Practice","author":"Van Dijk","year":"2003"},{"key":"key\n\t\t\t\t20170626100734_EHP314C13","first-page":"101","article-title":"Interval estimation for a binomial proportion","volume":"2","author":"Brown","year":"2001","journal-title":"Statistical Science"},{"key":"key\n\t\t\t\t20170626100734_EHP314C14","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s10286-004-1003-3","article-title":"Epidemiology of reflex syncope","volume":"14","author":"Colman","year":"2004","journal-title":"Clin Auton Res"},{"key":"key\n\t\t\t\t20170626100734_EHP314C15","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/j.amjcard.2005.07.047","article-title":"Relation of clinical presentation of syncope to the age of patients","volume":"10","author":"Del Rosso","year":"2005","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20170626100734_EHP314C16","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s10286-008-0465-0","article-title":"Influence of age and gender on the occurrence and presentation of reflex syncope","volume":"3","author":"Romme","year":"2008","journal-title":"Clin Auton Res"},{"key":"key\n\t\t\t\t20170626100734_EHP314C17","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1002\/(SICI)1097-0258(19970515)16:9<981::AID-SIM510>3.0.CO;2-N","article-title":"Variation of sensitivity, specificity, likelihood ratios and predictive values with disease prevalence","volume":"9","author":"Brenner","year":"1997","journal-title":"Stat Med"},{"key":"key\n\t\t\t\t20170626100734_EHP314C18","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/sim.1591","article-title":"Spectrum bias: a quantitative and graphical analysis of the variability of medical diagnostic test performance","volume":"1","author":"Goehring","year":"2004","journal-title":"Stat Med"},{"key":"key\n\t\t\t\t20170626100734_EHP314C19","doi-asserted-by":"crossref","first-page":"135","DOI":"10.7326\/0003-4819-117-2-135","article-title":"Spectrum bias in the evaluation of diagnostic tests: lessons from the rapid dipstick test for urinary tract infection","volume":"2","author":"Lachs","year":"1992","journal-title":"Ann Intern Med"},{"key":"key\n\t\t\t\t20170626100734_EHP314C20","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1373\/clinchem.2005.048595","article-title":"Case-control and two-gate designs in diagnostic accuracy studies","volume":"8","author":"Rutjes","year":"2005","journal-title":"Clin Chem"},{"issue":"50","key":"key\n\t\t\t\t20170626100734_EHP314C21","doi-asserted-by":"crossref","DOI":"10.3310\/hta11500","article-title":"Evaluation of diagnostic tests when there is no gold standard. A review of methods","volume":"11","author":"Rutjes","year":"2007","journal-title":"Health Technol Assess"},{"key":"key\n\t\t\t\t20170626100734_EHP314C22","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1016\/S0735-1097(01)01241-4","article-title":"Diagnostic value of history in patients with syncope with or without heart disease","volume":"7","author":"Alboni","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170626100734_EHP314C23","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1016\/j.jclinepi.2004.01.020","article-title":"Penalized maximum likelihood estimation to directly adjust diagnostic and prognostic prediction models for overoptimism: a clinical example","volume":"12","author":"Moons","year":"2004","journal-title":"J Clin Epidemiol"},{"key":"key\n\t\t\t\t20170626100734_EHP314C24","first-page":"194","article-title":"On the problem of using \u2018optimal\u2019 cutpoints in the assessment of quantitative prognostic factors","volume":"2","author":"Hollander","year":"2001","journal-title":"Onkologie"},{"key":"key\n\t\t\t\t20170626100734_EHP314C25","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1001\/jama.284.1.79","article-title":"Users\u2019 guides to the medical literature: XXII: how to use articles about clinical decision rules. Evidence-Based Medicine Working Group","volume":"1","author":"McGinn","year":"2000","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20170626100734_EHP314C26","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/S0895-4356(03)00207-5","article-title":"External validation is necessary in prediction research: a clinical example","volume":"9","author":"Bleeker","year":"2003","journal-title":"J Clin Epidemiol"},{"key":"key\n\t\t\t\t20170626100734_EHP314C27","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1093\/oxfordjournals.aje.a114065","article-title":"Retrospective information from questionnaires. II. Intrarater reliability and comparison of questionnaire types","volume":"6","author":"Herrmann","year":"1985","journal-title":"Am J Epidemiol"},{"key":"key\n\t\t\t\t20170626100734_EHP314C28","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/S0140-6736(79)92330-4","article-title":"Instability of cerebral blood-flow in insulin-dependent diabetics","volume":"8154","author":"Dandona","year":"1979","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170626100734_EHP314C29","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1056\/NEJM198307283090401","article-title":"A prospective evaluation and follow-up of patients with syncope","volume":"4","author":"Kapoor","year":"1983","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170626100734_EHP314C30","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1097\/00005792-199005000-00004","article-title":"Evaluation and outcome of patients with syncope","volume":"3","author":"Kapoor","year":"1990","journal-title":"Medicine (Baltimore)"},{"key":"key\n\t\t\t\t20170626100734_EHP314C31","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0002-9343(82)90913-5","article-title":"Evaluation and outcome of emergency room patients with transient loss of consciousness","volume":"1","author":"Day","year":"1982","journal-title":"Am J Med"},{"key":"key\n\t\t\t\t20170626100734_EHP314C32","first-page":"63","article-title":"Syncope: etiology, prognosis, and relationship to age","volume":"1","author":"Dougnac","year":"1991","journal-title":"Aging (Milano)"}],"container-title":["European Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/eurheartj\/article-pdf\/30\/23\/2888\/17890249\/ehp314.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T22:48:40Z","timestamp":1710542920000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurheartj\/article-lookup\/doi\/10.1093\/eurheartj\/ehp314"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8,17]]},"references-count":32,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2009,8,17]]},"published-print":{"date-parts":[[2009,12]]}},"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/ehp314","relation":{},"ISSN":["1522-9645","0195-668X"],"issn-type":[{"value":"1522-9645","type":"electronic"},{"value":"0195-668X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,8,17]]}}}