{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:32:32Z","timestamp":1791045152416,"version":"4.1.0"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1093\/eurheartj\/ehq440","type":"journal-article","created":{"date-parts":[[2010,12,9]],"date-time":"2010-12-09T15:42:56Z","timestamp":1291909376000},"page":"500-508","source":"Crossref","is-referenced-by-count":98,"title":["Risk of congenital heart defects associated with assisted reproductive technologies: a population-based evaluation"],"prefix":"10.1093","volume":"32","author":[{"given":"Karim","family":"Tararbit","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucile","family":"Houyel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Bonnet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"De Vigan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Lelong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Goffinet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babak","family":"Khoshnood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2010,12,7]]},"reference":[{"key":"key\n\t\t\t\t20170515123402_EHQ440C1","article-title":"Final Activity Report to European Commission March 2004 to August 2007","author":"Eurocat"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C2","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.ahj.2003.05.003","article-title":"Prevalence of congenital heart disease","volume":"147","year":"2004","journal-title":"Am Heart J"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C3","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1161\/01.CIR.99.7.916","article-title":"Detection of transposition of the great arteries in fetuses reduces neonatal morbidity and mortality","volume":"99","year":"1999","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C4","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1542\/peds.2004-0516","article-title":"Trends in prenatal diagnosis, pregnancy termination, and perinatal mortality of newborns with congenital heart disease in France, 1983\u20132000: a population-based evaluation","volume":"115","year":"2005","journal-title":"Pediatrics"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C5","doi-asserted-by":"crossref","first-page":"3015","DOI":"10.1161\/CIRCULATIONAHA.106.183056","article-title":"Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics","volume":"115","year":"2007","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C6","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1161\/CIRCULATIONAHA.106.183216","article-title":"Noninherited risk factors and congenital cardiovascular defects: current knowledge: a scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics","volume":"115","year":"2007","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C7","doi-asserted-by":"crossref","first-page":"2310","DOI":"10.1093\/humrep\/dep098","article-title":"World collaborative report on Assisted Reproductive Technology, 2002","volume":"24","year":"2009","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C8","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1093\/humrep\/dep035","article-title":"Assisted reproductive technology and intrauterine inseminations in Europe, 2005: results generated from European registers by ESHRE: ESHRE. The European IVF Monitoring Programme (EIM), for the European Society of Human Reproduction and Embryology (ESHRE)","volume":"24","year":"2009","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C9","first-page":"733","article-title":"Impact of advanced maternal age on fecundity and women's and children's health","volume":"37","year":"2008","journal-title":"Journal de gynecologie, obstetrique et biologie de la reproduction"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C10","article-title":"Rapport annuel et bilan des activit\u00e9s 2007","author":"Agence de Biom\u00e9decine"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C11","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1016\/S0140-6736(99)04345-7","article-title":"Deliveries and children born after in-vitro fertilisation in Sweden 1982\u201395: a retrospective cohort study","volume":"354","year":"1999","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C12","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1016\/j.fertnstert.2003.10.053","article-title":"Pregnancy course and outcome after intracytoplasmic sperm injection: a controlled, prospective cohort study","volume":"81","year":"2004","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C13","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1093\/humrep\/17.5.1391","article-title":"Neonatal outcome and congenital malformations in children born after in-vitro fertilization","volume":"17","year":"2002","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C14","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1097\/01.AOG.0000124571.04890.67","article-title":"Are children born after assisted reproductive technology at increased risk for adverse health outcomes?","volume":"103","year":"2004","journal-title":"Obstet Gynecol"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C15","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0140-6736(07)60456-5","article-title":"Outcome of assisted reproduction","volume":"370","year":"2007","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C16","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1016\/j.fertnstert.2005.04.065","article-title":"Congenital abnormalities in children born after assisted reproductive techniques: how much is associated with the presence of infertility and how much with its treatment?","volume":"84","year":"2005","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C17","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1093\/humrep\/16.3.504","article-title":"Congenital malformations in infants born after IVF: a population-based study","volume":"16","year":"2001","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C18","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1093\/humrep\/deh593","article-title":"Assisted reproductive technologies and the risk of birth defects\u2014a systematic review","volume":"20","year":"2005","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C19","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1056\/NEJMoa010035","article-title":"The risk of major birth defects after intracytoplasmic sperm injection and in vitro fertilization","volume":"346","year":"2002","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C20","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1016\/j.fertnstert.2005.03.085","article-title":"Children born after assisted fertilization have an increased rate of major congenital anomalies","volume":"84","year":"2005","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C21","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1016\/j.fertnstert.2005.03.086","article-title":"In vitro fertilization is associated with an increase in major birth defects","volume":"84","year":"2005","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C22","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1016\/j.fertnstert.2005.04.066","article-title":"Risk of birth defects among children conceived with assisted reproductive technology: providing an epidemiologic context to the data","volume":"84","year":"2005","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C23","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1093\/humrep\/15.4.944","article-title":"Incidence of congenital malformations in children born after ICSI","volume":"15","year":"2000","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C24","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1093\/humrep\/17.8.2089","article-title":"Congenital malformations in 4224 children conceived after IVF","volume":"17","year":"2002","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C25","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1093\/ije\/dyh363","article-title":"Birth defects in children conceived by ICSI compared with children conceived by other IVF-methods; a meta-analysis","volume":"34","year":"2005","journal-title":"Int J Epidemiol"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C26","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1093\/humrep\/den387","article-title":"Assisted reproductive technology and major structural birth defects in the United States","volume":"24","year":"2009","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C27","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/S0368-2315(05)82966-7","article-title":"Prevalence and prenatal diagnosis of congenital malformations in the Parisian population: twenty years of surveillance by the Paris Registry of congenital malformations","volume":"34","year":"2005","journal-title":"Journal de gynecologie, obstetrique et biologie de la reproduction"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C28","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1097\/00001648-199303000-00017","article-title":"Normal or affected controls in case\u2013control studies of congenital malformations and other birth defects: reporting bias issues","volume":"4","year":"1993","journal-title":"Epidemiology"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C29","article-title":"Embryologie du coeur normal","year":"2009","journal-title":"EMC (Elsevier Masson SAS, Paris), Cardiologie"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C30","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1136\/adc.82.5.349","article-title":"Socioeconomic inequalities in risk of congenital anomaly","volume":"82","year":"2000","journal-title":"Arch Dis Child"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C31","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1093\/ije\/28.5.964","article-title":"The use of fractional polynomials to model continuous risk variables in epidemiology","volume":"28","year":"1999","journal-title":"Int J Epidemiol"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C32","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/00001648-199001000-00010","article-title":"No adjustments are needed for multiple comparisons","volume":"1","year":"1990","journal-title":"Epidemiology"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C33","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1093\/oxfordjournals.aje.a117737","article-title":"Multiple comparisons and related issues in the interpretation of epidemiologic data","volume":"142","year":"1995","journal-title":"Am J Epidemiol"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C34","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1093\/oxfordjournals.aje.a009666","article-title":"Attributable fraction for cardiac malformations","volume":"148","year":"1998","journal-title":"Am J Epidemiol"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C35","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.fertnstert.2009.01.002","article-title":"Imprinting disorders and assisted reproductive technology","volume":"91","year":"2009","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C36","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1097\/00001648-199905000-00008","article-title":"Selection bias and the use of controls with malformations in case\u2013control studies of birth defects","volume":"10","year":"1999","journal-title":"Epidemiology"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C37","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1097\/00001648-199207000-00011","article-title":"Reporting and selection bias in case\u2013control studies of congenital malformations","volume":"3","year":"1992","journal-title":"Epidemiology"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C38","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.2105\/AJPH.2005.069377","article-title":"Advances in medical technology and creation of disparities: the case of Down syndrome","volume":"96","year":"2006","journal-title":"Am J Public Health"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C39","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1111\/j.1528-1157.2000.tb00119.x","article-title":"Teratogenic effects of antiepileptic drugs: use of an International Database on Malformations and Drug Exposure (MADRE)","volume":"41","year":"2000","journal-title":"Epilepsia"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C40","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1212\/01.wnl.0000316194.98475.d8","article-title":"Does lamotrigine use in pregnancy increase orofacial cleft risk relative to other malformations?","volume":"71","year":"2008","journal-title":"Neurology"},{"issue":"Suppl. 4","key":"key\n\t\t\t\t20170515123402_EHQ440C41","first-page":"81","article-title":"Registration of congenital anomalies in ART populations: pitfalls","volume":"11","year":"1996","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C42","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1093\/oxfordjournals.aje.a010291","article-title":"Occurrence of congenital heart defects in relation to maternal mulitivitamin use","volume":"151","year":"2000","journal-title":"Am J Epidemiol"},{"key":"key\n\t\t\t\t20170515123402_EHQ440C43","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1136\/bmj.38919.495718.AE","article-title":"Infertility, infertility treatment, and congenital malformations: Danish national birth cohort","volume":"333","year":"2006","journal-title":"BMJ"},{"issue":"Suppl. 2","key":"key\n\t\t\t\t20170515123402_EHQ440C44","first-page":"1","article-title":"The nomenclature, definition and classification of cardiac structures in the setting of heterotaxy","volume":"17","year":"2007","journal-title":"Cardiol Young"}],"container-title":["European Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/eurheartj\/article-pdf\/32\/4\/500\/17049640\/ehq440.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T19:20:45Z","timestamp":1559848845000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurheartj\/article-lookup\/doi\/10.1093\/eurheartj\/ehq440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12,7]]},"references-count":44,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2010,12,7]]},"published-print":{"date-parts":[[2011,2]]}},"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/ehq440","relation":{},"ISSN":["0195-668X","1522-9645"],"issn-type":[{"value":"0195-668X","type":"print"},{"value":"1522-9645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,12,7]]}}}