{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:03:15Z","timestamp":1787241795190,"version":"build-2736575974"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,2,14]]},"DOI":"10.1093\/eurheartj\/ehs305","type":"journal-article","created":{"date-parts":[[2012,10,6]],"date-time":"2012-10-06T00:34:16Z","timestamp":1349483656000},"page":"529-539","source":"Crossref","is-referenced-by-count":137,"title":["Prevalence, correlates, and prognostic significance of QRS prolongation in heart failure with reduced and preserved ejection fraction"],"prefix":"10.1093","volume":"34","author":[{"given":"Lars H.","family":"Lund","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliane","family":"Jurga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Edner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Benson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulf","family":"Dahlstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Linde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urban","family":"Alehagen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2012,10,4]]},"reference":[{"key":"key\n\t\t\t\t20170626084041_EHS305C1","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.ejheart.2008.08.005","article-title":"ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008. The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM)","volume":"10","author":"Dickstein","year":"2008","journal-title":"Eur J Heart Fail"},{"key":"key\n\t\t\t\t20170626084041_EHS305C2","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1056\/NEJMoa052256","article-title":"Trends in prevalence and outcome of heart failure with preserved ejection fraction","volume":"355","author":"Owan","year":"2006","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170626084041_EHS305C3","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1056\/NEJMoa051530","article-title":"Outcome of heart failure with preserved ejection fraction in a population-based study","volume":"355","author":"Bhatia","year":"2006","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170626084041_EHS305C4","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.amjcard.2010.04.021","article-title":"Relation of QRS width in healthy persons to risk of future permanent pacemaker implantation","volume":"106","author":"Cheng","year":"2010","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C5","doi-asserted-by":"crossref","first-page":"2494","DOI":"10.1161\/01.CIR.98.22.2494","article-title":"Bundle-branch block in a general male population: the study of men born 1913","volume":"98","author":"Eriksson","year":"1998","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170626084041_EHS305C6","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.amjcard.2006.03.044","article-title":"Prognostic significance of incident complete left bundle branch block observed over a 40-year period","volume":"98","author":"Imanishi","year":"2006","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C7","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.amjcard.2005.08.046","article-title":"Comparison of mortality risk for electrocardiographic abnormalities in men and women with and without coronary heart disease (from the Cardiovascular Health Study)","volume":"97","author":"Rautaharju","year":"2006","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C8","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1067\/mhj.2002.121264","article-title":"Left bundle-branch block is associated with increased 1-year sudden and total mortality rate in 5517 outpatients with congestive heart failure: a report from the Italian network on congestive heart failure","volume":"143","author":"Baldasseroni","year":"2002","journal-title":"Am Heart J"},{"key":"key\n\t\t\t\t20170626084041_EHS305C9","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.ejheart.2006.11.006","article-title":"Prevalence and prognostic impact of bundle branch block in patients with heart failure: evidence from the CHARM programme","volume":"9","author":"Hawkins","year":"2007","journal-title":"Eur J Heart Fail"},{"key":"key\n\t\t\t\t20170626084041_EHS305C10","doi-asserted-by":"crossref","first-page":"2656","DOI":"10.1001\/jama.299.22.2656","article-title":"Clinical implications of QRS duration in patients hospitalized with worsening heart failure and reduced left ventricular ejection fraction","volume":"299","author":"Wang","year":"2008","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20170626084041_EHS305C11","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.cardfail.2008.07.238","article-title":"Prognostic importance of change in QRS duration over time associated with left ventricular dysfunction in patients with congestive heart failure: the DIAMOND study","volume":"14","author":"Fosbol","year":"2008","journal-title":"J Card Fail"},{"key":"key\n\t\t\t\t20170626084041_EHS305C12","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1093\/eurheartj\/ehm262","article-title":"Influence of left bundle branch block on long-term mortality in a population with heart failure","volume":"28","author":"Tabrizi","year":"2007","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20170626084041_EHS305C13","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.amjcard.2010.10.007","article-title":"Relation of bundle branch block to long-term (four-year) mortality in hospitalized patients with systolic heart failure","volume":"107","author":"Barsheshet","year":"2011","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C14","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.amjcard.2005.08.031","article-title":"Comparison of six-month outcomes and hospitalization rates in heart failure patients with and without preserved left ventricular ejection fraction and with and without intraventricular conduction defect","volume":"97","author":"Danciu","year":"2006","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C15","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1001\/jama.2010.1949","article-title":"Association of candesartan vs losartan with all-cause mortality in patients with heart failure","volume":"305","author":"Eklind-Cervenka","year":"2011","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20170626084041_EHS305C16","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1093\/eurjhf\/hfp175","article-title":"Heart failure registry: a valuable tool for improving the management of patients with heart failure","volume":"12","author":"Jonsson","year":"2010","journal-title":"Eur J Heart Fail"},{"key":"key\n\t\t\t\t20170626084041_EHS305C17","doi-asserted-by":"crossref","DOI":"10.1002\/0471722146","volume-title":"Applied Logistic Regression","author":"Hosmer","year":"2000","edition":"2nd ed"},{"key":"key\n\t\t\t\t20170626084041_EHS305C18","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4757-3294-8","volume-title":"Modeling Survival Data: Extending the Cox Model","author":"Therneau","year":"2000"},{"key":"key\n\t\t\t\t20170626084041_EHS305C19","doi-asserted-by":"crossref","first-page":"426","DOI":"10.7326\/0003-4819-58-3-426","article-title":"Primary myocardial disease: part I: clinical features","volume":"58","author":"Dye","year":"1963","journal-title":"Ann Intern Med"},{"key":"key\n\t\t\t\t20170626084041_EHS305C20","doi-asserted-by":"crossref","first-page":"H2336","DOI":"10.1152\/ajpheart.00517.2008","article-title":"Ventricular activation is impaired in aged rat hearts.","volume":"295","author":"Rossi","year":"2008","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C21","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.amjcard.2003.09.053","article-title":"Prevalence of QRS prolongation in a community hospital cohort of patients with heart failure and its relation to left ventricular systolic dysfunction","volume":"93","author":"Sandhu","year":"2004","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C22","doi-asserted-by":"crossref","first-page":"2539","DOI":"10.1093\/eurheartj\/ehm037","article-title":"How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology","volume":"28","author":"Paulus","year":"2007","journal-title":"Eur Heart J"},{"issue":"1 Pt 2","key":"key\n\t\t\t\t20170626084041_EHS305C23","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1046\/j.1460-9592.2003.00010.x","article-title":"Beneficial effects of biventricular pacing in patients with a \u2018narrow\u2019 QRS","volume":"26","author":"Gasparini","year":"2003","journal-title":"Pacing Clin Electrophysiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C24","doi-asserted-by":"crossref","first-page":"143D","DOI":"10.1016\/S0002-9149(98)01016-9","article-title":"Potential benefit of biventricular pacing in patients with congestive heart failure and ventricular tachyarrhythmia","volume":"83","author":"Stellbrink","year":"1999","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C25","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1016\/j.amjcard.2009.07.012","article-title":"Prognostic significance of QRS duration in patients with suspected coronary artery disease referred for noninvasive evaluation of myocardial ischemia","volume":"104","author":"Schinkel","year":"2009","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C26","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.jacc.2010.06.061","article-title":"Cardiac resynchronization therapy is more effective in women than in men: the MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchronization Therapy) trial","volume":"57","author":"Arshad","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C27","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1093\/europace\/eus039","article-title":"Women have better long-term prognosis than men after cardiac resynchronization therapy","volume":"14","author":"Zabarovskaja","year":"2012","journal-title":"Europace"},{"key":"key\n\t\t\t\t20170626084041_EHS305C28","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.ijcard.2005.01.045","article-title":"The prognostic significance of horizontal plane QRS axis in elderly heart failure","volume":"106","author":"Xiao","year":"2006","journal-title":"Int J Cardiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C29","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1111\/j.1540-8159.1999.tb00350.x","article-title":"Evolution of QRS duration after myocardial infarction: clinical consequences","volume":"22","author":"Brembilla-Perrot","year":"1999","journal-title":"Pacing Clin Electrophysiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C30","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.amjmed.2005.08.028","article-title":"Prognostic significance of quantitative QRS duration","volume":"119","author":"Desai","year":"2006","journal-title":"Am J Med"},{"key":"key\n\t\t\t\t20170626084041_EHS305C31","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1093\/oxfordjournals.eurheartj.a062172","article-title":"Left bundle branch block: prevalence, incidence, follow-up and outcome","volume":"8","author":"Hardarson","year":"1987","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20170626084041_EHS305C32","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1056\/NEJMoa0906431","article-title":"Cardiac-resynchronization therapy for the prevention of heart-failure events","volume":"361","author":"Moss","year":"2009","journal-title":"New Engl J Med"},{"key":"key\n\t\t\t\t20170626084041_EHS305C33","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1016\/j.jacc.2008.08.027","article-title":"Randomized trial of cardiac resynchronization in mildly symptomatic heart failure patients and in asymptomatic patients with left ventricular dysfunction and previous heart failure symptoms","volume":"52","author":"Linde","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170626084041_EHS305C34","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1093\/eurheartj\/ehq337","article-title":"2010 Focused Update of ESC Guidelines on device therapy in heart failure: An update of the 2008 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure and the 2007. ESC Guidelines for cardiac and resynchronization therapy. Developed with the special contribution of the Heart Failure Association and the European Heart Rhythm Association","volume":"31","author":"Dickstein","year":"2010","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20170626084041_EHS305C35","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1161\/CIRCULATIONAHA.110.960898","article-title":"Effectiveness of cardiac resynchronization therapy by QRS morphology in the Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADIT-CRT)","volume":"123","author":"Zareba","year":"2011","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170626084041_EHS305C36","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1093\/eurjhf\/hfq009","article-title":"Cardiac resynchronization therapy may benefit patients with left ventricular ejection fraction >35%: a PROSPECT trial substudy","volume":"12","author":"Chung","year":"2010","journal-title":"Eur J Heart Fail"},{"key":"key\n\t\t\t\t20170626084041_EHS305C37","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1016\/j.jacc.2005.01.071","article-title":"Significance of QRS complex duration in patients with heart failure","volume":"46","author":"Kashani","year":"2005","journal-title":"J Am Coll Cardiol"}],"container-title":["European Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/eurheartj\/article-pdf\/34\/7\/529\/17897480\/ehs305.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,4]],"date-time":"2019-07-04T08:50:59Z","timestamp":1562230259000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurheartj\/article-lookup\/doi\/10.1093\/eurheartj\/ehs305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,4]]},"references-count":37,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2012,10,4]]},"published-print":{"date-parts":[[2013,2,14]]}},"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/ehs305","relation":{},"ISSN":["1522-9645","0195-668X"],"issn-type":[{"value":"1522-9645","type":"electronic"},{"value":"0195-668X","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10,4]]}}}