{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T02:17:31Z","timestamp":1790648251557,"version":"4.1.0"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"48","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,12,21]]},"DOI":"10.1093\/eurheartj\/ehu314","type":"journal-article","created":{"date-parts":[[2014,8,25]],"date-time":"2014-08-25T20:17:23Z","timestamp":1408997843000},"page":"3434-3441","source":"Crossref","is-referenced-by-count":96,"title":["Post-translational modifications enhance NT-proBNP and BNP production in acute decompensated heart failure"],"prefix":"10.1093","volume":"35","author":[{"given":"Nicolas","family":"Vodovar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-France","family":"S\u00e9ronde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Said","family":"Laribi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne","family":"Gayat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Lassus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riadh","family":"Boukef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Semir","family":"Nouira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Manivet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane-Lise","family":"Samuel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Logeart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiro","family":"Ishihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Cohen Solal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"James L.","family":"Januzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Mark","family":"Richards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Marie","family":"Launay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Mebazaa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,8,25]]},"reference":[{"key":"key\n\t\t\t\t20170516123132_EHU314C1","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1093\/eurheartj\/ehs104","article-title":"ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC","volume":"33","author":"McMurray","year":"2012","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20170516123132_EHU314C2","doi-asserted-by":"crossref","first-page":"e147","DOI":"10.1016\/j.jacc.2013.05.019","article-title":"2013 ACCF\/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines","volume":"62","author":"Yancy","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170516123132_EHU314C3","doi-asserted-by":"crossref","first-page":"3404","DOI":"10.1016\/j.ijcard.2013.04.164","article-title":"Comparison of the diagnostic and prognostic values of B-type and atrial-type natriuretic peptides in acute heart failure","volume":"168","author":"Seronde","year":"2013","journal-title":"Int J Cardiol"},{"key":"key\n\t\t\t\t20170516123132_EHU314C4","doi-asserted-by":"crossref","first-page":"e58287","DOI":"10.1371\/journal.pone.0058287","article-title":"Natriuretic peptide-guided therapy in chronic heart failure: a meta-analysis of 2,686 patients in 12 randomized trials","volume":"8","author":"Savarese","year":"2013","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170516123132_EHU314C5","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1172\/JCI118162","article-title":"Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an \u2018emergency\u2019 cardiac hormone against ventricular overload","volume":"96","author":"Nakagawa","year":"1995","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20170516123132_EHU314C6","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1373\/clinchem.2010.143883","article-title":"Processing of pro-B-type natriuretic peptide: furin and corin as candidate convertases","volume":"56","author":"Semenov","year":"2010","journal-title":"Clin Chem"},{"key":"key\n\t\t\t\t20170516123132_EHU314C7","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1373\/clinchem.2010.157438","article-title":"Secretion of glycosylated pro-B-type natriuretic peptide from normal cardiomyocytes","volume":"57","author":"Tonne","year":"2011","journal-title":"Clin Chem"},{"key":"key\n\t\t\t\t20170516123132_EHU314C8","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.abb.2006.03.028","article-title":"The precursor to B-type natriuretic peptide is an O-linked glycoprotein","volume":"451","author":"Schellenberger","year":"2006","journal-title":"Arch Biochem Biophys"},{"key":"key\n\t\t\t\t20170516123132_EHU314C9","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1373\/clinchem.2008.113373","article-title":"Processing of pro-brain natriuretic peptide is suppressed by O-glycosylation in the region close to the cleavage site","volume":"55","author":"Semenov","year":"2009","journal-title":"Clin Chem"},{"key":"key\n\t\t\t\t20170516123132_EHU314C10","doi-asserted-by":"crossref","first-page":"H17","DOI":"10.1152\/ajpheart.00684.2005","article-title":"Cardiac endocrine function is an essential component of the homeostatic regulation network: physiological and clinical implications","volume":"290","author":"Clerico","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"key\n\t\t\t\t20170516123132_EHU314C11","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1161\/CIRCHEARTFAILURE.109.903849","article-title":"Plasma soluble corin in patients with heart failure","volume":"3","author":"Dong","year":"2010","journal-title":"Circ Heart Fail"},{"key":"key\n\t\t\t\t20170516123132_EHU314C12","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1006\/bbrc.1993.2145","article-title":"Characterization of a secreted form of human furin endoprotease","volume":"195","author":"Vidricaire","year":"1993","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t20170516123132_EHU314C13","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1373\/clinchem.2005.061770","article-title":"Assay for measurement of intact B-type natriuretic peptide prohormone in blood","volume":"52","author":"Giuliani","year":"2006","journal-title":"Clin Chem"},{"key":"key\n\t\t\t\t20170516123132_EHU314C14","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.jchromb.2009.02.040","article-title":"Coupling of a vented column with splitless nanoRPLC-ESI-MS for the improved separation and detection of brain natriuretic peptide-32 and its proteolytic peptides","volume":"877","author":"Andrews","year":"2009","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"key\n\t\t\t\t20170516123132_EHU314C15","doi-asserted-by":"crossref","first-page":"25847","DOI":"10.1074\/jbc.M301223200","article-title":"Furin-mediated processing of Pro-C-type natriuretic peptide","volume":"278","author":"Wu","year":"2003","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170516123132_EHU314C16","doi-asserted-by":"crossref","first-page":"8525","DOI":"10.1073\/pnas.150149097","article-title":"Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme","volume":"97","author":"Yan","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170516123132_EHU314C17","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1021\/jm9012455","article-title":"Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics","volume":"53","author":"Becker","year":"2010","journal-title":"J Med Chem"},{"key":"key\n\t\t\t\t20170516123132_EHU314C18","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/j.1365-2796.2008.01934.x","article-title":"Use of B-type natriuretic peptide in the risk stratification of community-acquired pneumonia","volume":"264","author":"Christ-Crain","year":"2008","journal-title":"J Intern Med"},{"key":"key\n\t\t\t\t20170516123132_EHU314C19","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/s00392-010-0140-z","article-title":"Inflammation increases NT-proBNP and the NT-proBNP\/BNP ratio","volume":"99","author":"Jensen","year":"2010","journal-title":"Clin Res Cardiol"},{"key":"key\n\t\t\t\t20170516123132_EHU314C20","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1097\/CCM.0b013e318183f067","article-title":"Impaired plasma B-type natriuretic peptide clearance in human septic shock","volume":"36","author":"Pirracchio","year":"2008","journal-title":"Crit Care Med"},{"key":"key\n\t\t\t\t20170516123132_EHU314C21","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1111\/j.1742-1241.2007.01305.x","article-title":"Assessment of B-type natriuretic peptide in patients with pneumonia","volume":"62","author":"Yetkin","year":"2008","journal-title":"Int J Clin Pract"},{"key":"key\n\t\t\t\t20170516123132_EHU314C22","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1373\/clinchem.2007.097998","article-title":"Cross-reactivity of BNP, NT-proBNP, and proBNP in commercial BNP and NT-proBNP assays: preliminary observations from the IFCC Committee for Standardization of Markers of Cardiac Damage","volume":"54","author":"Luckenbill","year":"2008","journal-title":"Clin Chem"},{"key":"key\n\t\t\t\t20170516123132_EHU314C23","doi-asserted-by":"crossref","first-page":"e75174","DOI":"10.1371\/journal.pone.0075174","article-title":"Depletion of proBNP1\u2013108 in patients with heart failure prevents cross-reactivity with natriuretic peptides","volume":"8","author":"Roubille","year":"2013","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170516123132_EHU314C24","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1373\/clinchem.2007.100040","article-title":"Immunodetection of glycosylated NT-proBNP circulating in human blood","volume":"54","author":"Seferian","year":"2008","journal-title":"Clin Chem"},{"key":"key\n\t\t\t\t20170516123132_EHU314C25","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1161\/01.HYP.36.3.355","article-title":"Deconvolution analysis of cardiac natriuretic peptides during acute volume overload","volume":"36","author":"Pemberton","year":"2000","journal-title":"Hypertension"},{"key":"key\n\t\t\t\t20170516123132_EHU314C26","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1136\/heartjnl-2011-300102","article-title":"The effect of glycosylation on plasma N-terminal proBNP-76 levels in patients with heart or renal failure","volume":"98","author":"Nishikimi","year":"2012","journal-title":"Heart"}],"container-title":["European Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/eurheartj\/article-pdf\/35\/48\/3434\/17154627\/ehu314.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T08:51:01Z","timestamp":1503564661000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurheartj\/article-lookup\/doi\/10.1093\/eurheartj\/ehu314"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,25]]},"references-count":26,"journal-issue":{"issue":"48","published-online":{"date-parts":[[2014,8,25]]},"published-print":{"date-parts":[[2014,12,21]]}},"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/ehu314","relation":{},"ISSN":["1522-9645","0195-668X"],"issn-type":[{"value":"1522-9645","type":"electronic"},{"value":"0195-668X","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8,25]]}}}