{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:20:23Z","timestamp":1790734823412,"version":"4.1.0"},"reference-count":117,"publisher":"Oxford University Press (OUP)","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Heart J"],"published-print":{"date-parts":[[2016,6,14]]},"DOI":"10.1093\/eurheartj\/ehw018","type":"journal-article","created":{"date-parts":[[2016,2,24]],"date-time":"2016-02-24T21:23:47Z","timestamp":1456349027000},"page":"1799-1806","source":"Crossref","is-referenced-by-count":126,"title":["Coronary microvascular dysfunction in chronic inflammatory rheumatoid diseases"],"prefix":"10.1093","volume":"37","author":[{"given":"Alessia","family":"Faccini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Kaski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo G.","family":"Camici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,2,23]]},"reference":[{"key":"2016061709421900000_37.23.1799.1","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nrcardio.2014.206","article-title":"Cardiorheumatology: cardiac involvement in systemic rheumatic disease","volume":"12","author":"Prasad","year":"2015","journal-title":"Nat Rev Cardiol"},{"key":"2016061709421900000_37.23.1799.2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.009990"},{"key":"2016061709421900000_37.23.1799.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.11.048"},{"key":"2016061709421900000_37.23.1799.4","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu403"},{"key":"2016061709421900000_37.23.1799.5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199901143400207"},{"key":"2016061709421900000_37.23.1799.6","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.114.002235"},{"key":"2016061709421900000_37.23.1799.7","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2009.183327"},{"key":"2016061709421900000_37.23.1799.8","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/nrcardio.2014.160","article-title":"Coronary microvascular dysfunction: mechanisms and functional assessment","volume":"12","author":"Camici","year":"2015","journal-title":"Nat Rev Cardiol"},{"key":"2016061709421900000_37.23.1799.9","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvn136"},{"key":"2016061709421900000_37.23.1799.10","first-page":"75","article-title":"Myocardial blood flow measurement by PET: technical aspects and clinical applications","volume":"46","author":"Kaufmann","year":"2005","journal-title":"J Nucl Med"},{"key":"2016061709421900000_37.23.1799.11","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.76.2.245"},{"key":"2016061709421900000_37.23.1799.12","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.108.054478"},{"key":"2016061709421900000_37.23.1799.13","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.009716"},{"key":"2016061709421900000_37.23.1799.14","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht513"},{"key":"2016061709421900000_37.23.1799.15","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.84.5.1984"},{"key":"2016061709421900000_37.23.1799.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2010.04.007"},{"key":"2016061709421900000_37.23.1799.17","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1001508"},{"key":"2016061709421900000_37.23.1799.18","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00554-9"},{"key":"2016061709421900000_37.23.1799.19","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(75)90555-X"},{"key":"2016061709421900000_37.23.1799.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2008.03.006"},{"key":"2016061709421900000_37.23.1799.21","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs246"},{"key":"2016061709421900000_37.23.1799.22","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01067.2001"},{"key":"2016061709421900000_37.23.1799.23","doi-asserted-by":"publisher","DOI":"10.1097\/01.mca.0000134590.99841.81"},{"key":"2016061709421900000_37.23.1799.24","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1056\/NEJMra061889","article-title":"Coronary microvascular dysfunction","volume":"365","author":"Camici","year":"2007","journal-title":"N Engl J Med"},{"key":"2016061709421900000_37.23.1799.25","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.01.005"},{"key":"2016061709421900000_37.23.1799.26","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000054612.26458.B2"},{"key":"2016061709421900000_37.23.1799.27","doi-asserted-by":"publisher","DOI":"10.1002\/art.24092"},{"key":"2016061709421900000_37.23.1799.28","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22173"},{"key":"2016061709421900000_37.23.1799.29","doi-asserted-by":"publisher","DOI":"10.1007\/s11883-015-0497-6"},{"key":"2016061709421900000_37.23.1799.30","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009122"},{"key":"2016061709421900000_37.23.1799.31","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-014-2681-4"},{"key":"2016061709421900000_37.23.1799.32","doi-asserted-by":"publisher","DOI":"10.1186\/ar4267"},{"key":"2016061709421900000_37.23.1799.33","doi-asserted-by":"crossref","first-page":"2597","DOI":"10.1161\/01.CIR.0000099844.31524.05","article-title":"Explaining how \u2018high-grade\u2019 systemic inflammation accelerates vascular risk in rheumatoid arthritis","volume":"108","author":"Sattar","year":"2003","journal-title":"Circulation"},{"key":"2016061709421900000_37.23.1799.34","unstructured":"Roldan PC , Ratliff M , Snider R , Macias L , Rodriguez R , Sibbitt W , Roldan CA . Aortic atherosclerosis in systemic lupus erythematosus. Rheumatology (Sunnyvale) 2014;(Suppl. 5):S5\u2013006."},{"key":"2016061709421900000_37.23.1799.35","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2007.11.013"},{"key":"2016061709421900000_37.23.1799.36","doi-asserted-by":"publisher","DOI":"10.1002\/art.22702"},{"key":"2016061709421900000_37.23.1799.37","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp205"},{"key":"2016061709421900000_37.23.1799.38","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-14-1114"},{"key":"2016061709421900000_37.23.1799.39","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ker275"},{"key":"2016061709421900000_37.23.1799.40","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1161\/01.ATV.0000051384.43104.FC","article-title":"Endothelial dysfunction: a marker of atherosclerotic risk","volume":"23","author":"Bonetti","year":"2002","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"2016061709421900000_37.23.1799.41","doi-asserted-by":"publisher","DOI":"10.3390\/ijms150711324"},{"key":"2016061709421900000_37.23.1799.42","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204715"},{"key":"2016061709421900000_37.23.1799.43","first-page":"8","article-title":"Cardiovascular disease in systemic sclerosis","volume":"3","author":"Cannarile","year":"2015","journal-title":"Ann Transl Med"},{"key":"2016061709421900000_37.23.1799.44","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ken395"},{"key":"2016061709421900000_37.23.1799.45","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.09.074"},{"key":"2016061709421900000_37.23.1799.46","first-page":"409","article-title":"The effect of reactive oxygen species on the synthesis of prostanoids from arachidonic acid","volume":"64","author":"Korbecki","year":"2013","journal-title":"J Physiol Pharmacol"},{"key":"2016061709421900000_37.23.1799.47","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2012.01797.x"},{"key":"2016061709421900000_37.23.1799.48","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080342"},{"key":"2016061709421900000_37.23.1799.49","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00346.2011"},{"key":"2016061709421900000_37.23.1799.50","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2006070707"},{"key":"2016061709421900000_37.23.1799.51","doi-asserted-by":"publisher","DOI":"10.1111\/imm.12506"},{"key":"2016061709421900000_37.23.1799.52","doi-asserted-by":"publisher","DOI":"10.1016\/S0047-6374(97)00161-9"},{"key":"2016061709421900000_37.23.1799.53","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.013710"},{"key":"2016061709421900000_37.23.1799.54","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199812)41:12<2108::AID-ART5>3.0.CO;2-Q"},{"key":"2016061709421900000_37.23.1799.55","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvn248"},{"key":"2016061709421900000_37.23.1799.56","doi-asserted-by":"publisher","DOI":"10.1186\/ar2286"},{"key":"2016061709421900000_37.23.1799.57","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000057997.77714.72"},{"key":"2016061709421900000_37.23.1799.58","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.817528"},{"key":"2016061709421900000_37.23.1799.59","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.2.185"},{"key":"2016061709421900000_37.23.1799.60","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.1365-2796.2006.01753.x","article-title":"Hypercholesterolaemia impairs monocyte function in CAD patients","volume":"261","author":"Czepluch","year":"2007","journal-title":"J Intern Med"},{"key":"2016061709421900000_37.23.1799.61","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000250614.97896.4c"},{"key":"2016061709421900000_37.23.1799.62","doi-asserted-by":"publisher","DOI":"10.1111\/cei.12667"},{"key":"2016061709421900000_37.23.1799.63","doi-asserted-by":"publisher","DOI":"10.1002\/art.39419"},{"key":"2016061709421900000_37.23.1799.64","doi-asserted-by":"publisher","DOI":"10.1177\/0961203315598014"},{"key":"2016061709421900000_37.23.1799.65","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2014.12.025"},{"key":"2016061709421900000_37.23.1799.66","doi-asserted-by":"publisher","DOI":"10.3109\/1354750X.2012.728623"},{"key":"2016061709421900000_37.23.1799.67","doi-asserted-by":"publisher","DOI":"10.1155\/2009\/504294"},{"key":"2016061709421900000_37.23.1799.68","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2613-1"},{"key":"2016061709421900000_37.23.1799.69","doi-asserted-by":"publisher","DOI":"10.1097\/RHU.0b013e31827846b1"},{"key":"2016061709421900000_37.23.1799.70","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e3280b0157e"},{"key":"2016061709421900000_37.23.1799.71","doi-asserted-by":"publisher","DOI":"10.1186\/ar3374"},{"key":"2016061709421900000_37.23.1799.72","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2006.05.034"},{"key":"2016061709421900000_37.23.1799.73","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kep082"},{"key":"2016061709421900000_37.23.1799.74","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60279-7"},{"key":"2016061709421900000_37.23.1799.75","doi-asserted-by":"publisher","DOI":"10.1177\/000331979905000208"},{"key":"2016061709421900000_37.23.1799.76","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2010.09.019"},{"key":"2016061709421900000_37.23.1799.77","first-page":"292","article-title":"Brachial endothelial function is impaired in patients with systemic lupus erythematosus","volume":"29","author":"Lima","year":"2002","journal-title":"J Rheumatol"},{"key":"2016061709421900000_37.23.1799.78","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-008-8106-x"},{"key":"2016061709421900000_37.23.1799.79","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780280607"},{"key":"2016061709421900000_37.23.1799.80","doi-asserted-by":"publisher","DOI":"10.1136\/ard.62.9.890"},{"key":"2016061709421900000_37.23.1799.81","doi-asserted-by":"publisher","DOI":"10.1002\/acr.21819"},{"key":"2016061709421900000_37.23.1799.82","doi-asserted-by":"publisher","DOI":"10.1186\/ar4136"},{"key":"2016061709421900000_37.23.1799.83","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1161\/01.CIR.0000116601.58103.62","article-title":"Pathophysiology and management of patients with chest pain and normal coronary arteriograms (cardiac syndrome X)","volume":"109","author":"Kaski","year":"2004","journal-title":"Circulation"},{"key":"2016061709421900000_37.23.1799.84","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.020594"},{"key":"2016061709421900000_37.23.1799.85","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2012.12.011"},{"key":"2016061709421900000_37.23.1799.86","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2004.05.001"},{"key":"2016061709421900000_37.23.1799.87","first-page":"1074","article-title":"Endothelial dysfunction as assessed by flow-mediated dilation in patients with cardiac syndrome X: role of inflammation","volume":"15","author":"Tondi","year":"2011","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"2016061709421900000_37.23.1799.88","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu203"},{"key":"2016061709421900000_37.23.1799.89","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.122556"},{"key":"2016061709421900000_37.23.1799.90","first-page":"174","article-title":"Closing the loop on inflammation and atherothrombosis: why perform the CIRT and CANTOS trials?","volume":"124","author":"Ridker","year":"2013","journal-title":"Trans Am Clin Climatol Assoc"},{"key":"2016061709421900000_37.23.1799.91","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2009.03404.x"},{"key":"2016061709421900000_37.23.1799.92","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2014-206624"},{"key":"2016061709421900000_37.23.1799.93","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2011.06.054"},{"key":"2016061709421900000_37.23.1799.94","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2011.09.015"},{"key":"2016061709421900000_37.23.1799.95","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.771899"},{"key":"2016061709421900000_37.23.1799.96","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.282836"},{"key":"2016061709421900000_37.23.1799.97","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1315878"},{"key":"2016061709421900000_37.23.1799.98","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.11061"},{"key":"2016061709421900000_37.23.1799.99","doi-asserted-by":"publisher","DOI":"10.3109\/08916934.2015.1027818"},{"key":"2016061709421900000_37.23.1799.100","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61125-2"},{"key":"2016061709421900000_37.23.1799.101","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0807646"},{"key":"2016061709421900000_37.23.1799.102","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.9.839"},{"key":"2016061709421900000_37.23.1799.103","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16449-0"},{"key":"2016061709421900000_37.23.1799.104","first-page":"69","article-title":"The impact of statins therapy on disease activity and inflammatory factor in patients with rheumatoid arthritis: a meta-analysis","volume":"33","author":"Lv","year":"2014","journal-title":"Clin Exp Rheumatol"},{"key":"2016061709421900000_37.23.1799.105","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.12415"},{"key":"2016061709421900000_37.23.1799.106","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-202315"},{"key":"2016061709421900000_37.23.1799.107","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-203622"},{"key":"2016061709421900000_37.23.1799.108","doi-asserted-by":"publisher","DOI":"10.1186\/ar4285"},{"key":"2016061709421900000_37.23.1799.109","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keq003"},{"key":"2016061709421900000_37.23.1799.110","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-668X(03)00478-0"},{"key":"2016061709421900000_37.23.1799.111","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.03.003"},{"key":"2016061709421900000_37.23.1799.112","doi-asserted-by":"publisher","DOI":"10.1007\/s00005-009-0058-1"},{"key":"2016061709421900000_37.23.1799.113","doi-asserted-by":"crossref","first-page":"751793","DOI":"10.1155\/2015\/751793","article-title":"Altered immunoregulation in rheumatoid arthritis: the role of regulatory T cells and proinflammatory Th17 cells and therapeutic implications","volume":"2015","author":"Alunno","year":"2015","journal-title":"Mediators Inflamm"},{"key":"2016061709421900000_37.23.1799.114","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.012823"},{"key":"2016061709421900000_37.23.1799.115","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00389-1"},{"key":"2016061709421900000_37.23.1799.116","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-668X(03)00284-7"},{"key":"2016061709421900000_37.23.1799.117","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(02)03235-6"}],"container-title":["European Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/eurheartj\/article-pdf\/37\/23\/1799\/6733793\/ehw018.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T20:22:23Z","timestamp":1503519743000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurheartj\/article-lookup\/doi\/10.1093\/eurheartj\/ehw018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,23]]},"references-count":117,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2016,6,17]]},"published-print":{"date-parts":[[2016,6,14]]}},"alternative-id":["10.1093\/eurheartj\/ehw018"],"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/ehw018","relation":{},"ISSN":["0195-668X","1522-9645"],"issn-type":[{"value":"0195-668X","type":"print"},{"value":"1522-9645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,23]]}}}