{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T20:28:49Z","timestamp":1793996929727,"version":"4.8.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"31","license":[{"start":{"date-parts":[[2018,3,29]],"date-time":"2018-03-29T00:00:00Z","timestamp":1522281600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/about_us\/legal\/notices"}],"funder":[{"name":"Department of Cardiology"},{"name":"Leiden University Medical Centre"},{"name":"Edwards Lifesciences, Medtronik, Biotronik, and Boston Scientific","id":[{"id":"https:\/\/ror.org\/03kjsjz16","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,8,14]]},"DOI":"10.1093\/eurheartj\/ehy168","type":"journal-article","created":{"date-parts":[[2018,3,9]],"date-time":"2018-03-09T07:26:03Z","timestamp":1520580363000},"page":"2867-2875","source":"Crossref","is-referenced-by-count":152,"title":["Whole human heart histology to validate electroanatomical voltage mapping in patients with non-ischaemic cardiomyopathy and ventricular tachycardia"],"prefix":"10.1093","volume":"39","author":[{"given":"Claire A","family":"Glashan","sequence":"first","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Centre, Albinusdreef 2, 2333ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander F A","family":"Androulakis","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Centre, Albinusdreef 2, 2333ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Tao","sequence":"additional","affiliation":[{"name":"LKEB\u2013Division of Image Processing, Department of Radiology, Leiden University Medical Centre, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross N","family":"Glashan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Centre, Albinusdreef 2, 2333ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lambertus J","family":"Wisse","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Embryology, Leiden University Medical Centre, Albinusdreef 2, 2333ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micaela","family":"Ebert","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Centre, Albinusdreef 2, 2333ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco C","family":"de Ruiter","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Embryology, Leiden University Medical Centre, Albinusdreef 2, 2333ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berend J","family":"van Meer","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Embryology, Leiden University Medical Centre, Albinusdreef 2, 2333ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Brouwer","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Centre, Albinusdreef 2, 2333ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olaf M","family":"Dekkers","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel A","family":"Pijnappels","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Centre, Albinusdreef 2, 2333ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques M T","family":"de Bakker","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Cardiology, Academic Medical Centre, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"de Riva","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Centre, Albinusdreef 2, 2333ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastiaan R D","family":"Piers","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Centre, Albinusdreef 2, 2333ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Zeppenfeld","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Centre, Albinusdreef 2, 2333ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,3,29]]},"reference":[{"key":"key\n\t\t\t\t20180820094415_ehy168-B1","first-page":"704","article-title":"Characterization of endocardial electrophysiological substrate in patients with nonischemic cardiomyopathy and monomorphic ventricular tachycardia","volume":"108","author":"Hsia","year":"2003","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B2","first-page":"1834","article-title":"Endocardial and epicardial radiofrequency ablation of ventricular tachycardia associated with dilated cardiomyopathy: the importance of low-voltage scars","volume":"43","author":"Soejima","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B3","first-page":"389","article-title":"Cardiac fibrosis as a determinant of ventricular tachyarrhythmias","volume":"30","author":"Morita","year":"2014","journal-title":"J Arrhythm"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B4","first-page":"630","article-title":"Fibrosis and cardiac arrhythmias","volume":"57","author":"de Jong","year":"2011","journal-title":"J Cardiovasc Pharmacol"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B5","first-page":"3069","article-title":"Activation delay after premature stimulation in chronically diseased human myocardium relates to the architecture of interstitial fibrosis","volume":"104","author":"Kawara","year":"2001","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B6","first-page":"2793","article-title":"2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: The Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC). Endorsed by: association for European Paediatric and Congenital Cardiology (AEPC)","volume":"36","author":"Priori","year":"2015","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B7","first-page":"49","article-title":"Endocardial unipolar voltage mapping to detect epicardial ventricular tachycardia substrate in patients with nonischemic left ventricular cardiomyopathy","volume":"4","author":"Hutchinson","year":"2011","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B8","first-page":"891","article-title":"Characteristics of intramural scar in patients with nonischemic cardiomyopathy and relation to intramural ventricular arrhythmias","volume":"6","author":"Desjardins","year":"2013","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B9","first-page":"875","article-title":"Contrast-enhanced MRI-derived scar patterns and associated ventricular tachycardias in nonischemic cardiomyopathy: implications for the ablation strategy","volume":"6","author":"Piers","year":"2013","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B10","first-page":"2194","article-title":"New unipolar electrogram criteria to identify irreversibility of nonischemic left ventricular cardiomyopathy","volume":"60","author":"Campos","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B11","first-page":"1320","article-title":"Effect of epicardial fat on electroanatomical mapping and epicardial catheter ablation","volume":"56","author":"Desjardins","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B12","first-page":"2202","article-title":"Integration of cardiac magnetic resonance imaging with three-dimensional electroanatomic mapping to guide left ventricular catheter manipulation: feasibility in a porcine model of healed myocardial infarction","volume":"44","author":"Reddy","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B13","first-page":"589","article-title":"Reentry as a cause of ventricular tachycardia in patients with chronic ischemic heart disease: electrophysiologic and anatomic correlation","volume":"77","author":"de Bakker","year":"1988","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B14","first-page":"1288","article-title":"Linear ablation lesions for control of unmappable ventricular tachycardia in patients with ischemic and nonischemic cardiomyopathy","volume":"101","author":"Marchlinski","year":"2000","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B15","first-page":"586","article-title":"Epicardial substrate mapping for ventricular tachycardia ablation in patients with non-ischaemic cardiomyopathy: a new algorithm to differentiate between scar and viable myocardium developed by simultaneous integration of computed tomography and contrast-enhanced magnetic resonance imaging","volume":"34","author":"Piers","year":"2013","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B16","first-page":"1169","article-title":"Isolated septal substrate for ventricular tachycardia in nonischemic dilated cardiomyopathy: incidence, characterization, and implications","volume":"8","author":"Haqqani","year":"2011","journal-title":"Heart Rhythm"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B17","first-page":"1340","article-title":"Idiopathic dilated cardiomyopathy: analysis of 152 necropsy patients","volume":"60","author":"Roberts","year":"1987","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B18","first-page":"816","article-title":"Extent of myocardial fibrosis and cellular hypertrophy in dilated cardiomyopathy","volume":"57","author":"Unverferth","year":"1986","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B19","first-page":"299","article-title":"Histopathologic findings in explanted heart tissue from patients with end-stage idiopathic dilated cardiomyopathy","volume":"14","author":"de Leeuw","year":"2001","journal-title":"Transpl Int"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B20","first-page":"2404","article-title":"Mechanisms underlying spontaneous and induced ventricular arrhythmias in patients with idiopathic dilated cardiomyopathy","volume":"98","author":"Pogwizd","year":"1998","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B21","first-page":"14","article-title":"Histological validation of cardiac magnetic resonance analysis of regional and diffuse interstitial myocardial fibrosis","volume":"16","author":"Iles","year":"2015","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B22","first-page":"54","article-title":"Differentiation of heart failure related to dilated cardiomyopathy and coronary artery disease using gadolinium-enhanced cardiovascular magnetic resonance","volume":"108","author":"McCrohon","year":"2003","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B23","first-page":"2821","article-title":"Magnetic resonance assessment of the substrate for inducible ventricular tachycardia in nonischemic cardiomyopathy","volume":"112","author":"Nazarian","year":"2005","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B24","first-page":"896","article-title":"Association of fibrosis with mortality and sudden cardiac death in patients with nonischemic dilated cardiomyopathy","volume":"309","author":"Gulati","year":"2013","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B25","first-page":"1985","article-title":"Contrast-enhanced magnetic resonance imaging of myocardium at risk: distinction between reversible and irreversible injury throughout infarct healing","volume":"36","author":"Fieno","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B26","first-page":"104","article-title":"Head-to-head comparison of contrast-enhanced magnetic resonance imaging and electroanatomical voltage mapping to assess post-infarct scar characteristics in patients with ventricular tachycardias: real-time image integration and reversed registration","volume":"32","author":"Wijnmaalen","year":"2011","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B27","first-page":"2006","article-title":"Infarct tissue heterogeneity by magnetic resonance imaging identifies enhanced cardiac arrhythmia susceptibility in patients with left ventricular dysfunction","volume":"115","author":"Schmidt","year":"2007","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B28","first-page":"32","article-title":"Characterization of the peri-infarct zone by contrast-enhanced cardiac magnetic resonance imaging is a powerful predictor of post-myocardial infarction mortality","volume":"114","author":"Yan","year":"2006","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B29","first-page":"524","article-title":"Use of electrogram characteristics during sinus rhythm to delineate the endocardial scar in a porcine model of healed myocardial infarction","volume":"14","author":"Wrobleski","year":"2003","journal-title":"J Cardiovasc Electrophysiol"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B30","first-page":"1139","article-title":"Impact of nonischemic scar features on local ventricular electrograms and scar-related ventricular tachycardia circuits in patients with nonischemic cardiomyopathy","volume":"6","author":"Sasaki","year":"2013","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B31","first-page":"683","article-title":"Spread of activation in the left ventricular wall of the dog. I","volume":"46","author":"Durrer","year":"1953","journal-title":"Am Heart J"},{"key":"key\n\t\t\t\t20180820094415_ehy168-B32","first-page":"341","article-title":"Comparison of echocardiographic and necropsy measurements of ventricular wall thicknesses in patients with and without disproportionate septal thickening","volume":"55","author":"Maron","year":"1977","journal-title":"Circulation"}],"container-title":["European Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/eurheartj\/article-pdf\/39\/31\/2867\/25515613\/ehy168.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,8,20]],"date-time":"2018-08-20T09:45:41Z","timestamp":1534758341000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurheartj\/article\/39\/31\/2867\/4956395"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,29]]},"references-count":32,"journal-issue":{"issue":"31","published-online":{"date-parts":[[2018,3,29]]},"published-print":{"date-parts":[[2018,8,14]]}},"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/ehy168","relation":{},"ISSN":["0195-668X","1522-9645"],"issn-type":[{"value":"0195-668X","type":"print"},{"value":"1522-9645","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,8,14]]},"published":{"date-parts":[[2018,3,29]]}}}