{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T22:24:50Z","timestamp":1793831090168,"version":"4.6.1"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"38","license":[{"start":{"date-parts":[[2019,6,23]],"date-time":"2019-06-23T00:00:00Z","timestamp":1561248000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Peri-procedural transcatheter valve embolization and migration (TVEM) is a rare but potentially devastating complication of transcatheter aortic valve implantation (TAVI). We sought to assess the incidence, causes, and outcome of TVEM in a large multicentre cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We recorded cases of peri-procedural TVEM in patients undergoing TAVI between January 2010 and December 2017 from 26 international sites. Peri-procedural TVEM occurred in 273\/29\u00a0636 (0.92%) TAVI cases (age 80.8\u2009\u00b1\u20097.3\u2009years; 53.8% female), of which 217 were to the ascending aorta and 56 to the left ventricle. The use of self-expanding or first-generation prostheses and presence of a bicuspid aortic valve were independent predictors of TVEM. Bail-out measures included repositioning attempts using snares or miscellaneous tools (41.0%), multiple valve implantations (83.2%), and conversion to surgery (19.0%). Using 1:4-propensity matching, we identified a cohort of 235 patients with TVEM (TVEMPS) and 932 patients without TVEM (non-TVEMPS). In the matched cohort, all-cause mortality was higher in TVEMPS than in non-TVEMPS at 30\u2009days (18.6% vs. 4.9%; P\u2009&amp;lt;\u20090.001) and after 1\u2009year (30.5% vs. 16.6%; P\u2009&amp;lt;\u20090.001). Major stroke was more frequent in TVEMPS at 30\u2009days (10.6% vs. 2.8%; P\u2009&amp;lt;\u20090.001), but not at 1\u2009year (4.6% vs. 1.9%; P\u2009=\u20090.17). The need for emergent cardiopulmonary support, major stroke at 30\u2009days, and acute kidney injury Stages 2 and 3 increased the risk of 1-year mortality, whereas a better renal function at baseline was protective.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Transcatheter valve embolization and migration occurred in approximately 1% and was associated with increased morbidity and mortality.<\/jats:p>\n                    <jats:p\/>\n                  <\/jats:sec>","DOI":"10.1093\/eurheartj\/ehz429","type":"journal-article","created":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T07:08:51Z","timestamp":1559200131000},"page":"3156-3165","source":"Crossref","is-referenced-by-count":149,"title":["Incidence and outcome of peri-procedural transcatheter heart valve embolization and migration: the TRAVEL registry (TranscatheteR HeArt Valve EmboLization and Migration)"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0799-7478","authenticated-orcid":false,"given":"Won-Keun","family":"Kim","sequence":"first","affiliation":[{"name":"Kerckhoff Heart Center, Department of Cardiology , Bad Nauheim, Germany"},{"name":"DZHK (German Center for Cardiovascular Research), Partner Site Rhein-Main, Frankfurt am Main, Germany"},{"name":"Kerckhoff Heart Center Department of Cardiac Surgery, , Bad Nauheim, Germany"},{"name":"Justus-Liebig University of Giessen and Marburg Department of Cardiology, , Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Sch\u00e4fer","sequence":"additional","affiliation":[{"name":"University Heart Center Department of General and Interventional Cardiology, , University Hospital Hamburg-Eppendorf (UKE), Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Tchetche","sequence":"additional","affiliation":[{"name":"GCVI Groupe Cardiovasculaire Interventionel ( ), Clinique Pasteur, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Nef","sequence":"additional","affiliation":[{"name":"Justus-Liebig University of Giessen and Marburg Department of Cardiology, , Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Arnold","sequence":"additional","affiliation":[{"name":"Friedrich Alexander University Erlangen-N\u00fcrnberg Department of Cardiology, , Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Avanzas","sequence":"additional","affiliation":[{"name":"Hospital Universitario Central de Asturias Department of Cardiology, , Oviedo, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain"},{"name":"University of Oviedo Department of Medicine, , Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Rudolph","sequence":"additional","affiliation":[{"name":"University of Cologne Department of Cardiology, , Heart Center, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smita","family":"Scholtz","sequence":"additional","affiliation":[{"name":"Ruhr-University Bochum Department of Cardiology, Herz- und Diabeteszentrum NRW, , Bad Oeynhausen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4903-5437","authenticated-orcid":false,"given":"Marco","family":"Barbanti","sequence":"additional","affiliation":[{"name":"Policlinico-Vittorio Emanuele Hospital Division of Cardiology, , University of Catania, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Kempfert","sequence":"additional","affiliation":[{"name":"German Heart Center Berlin Department of Cardiothoracic and Vascular Surgery, , Berlin, Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Germany"},{"name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin Department of Cardiothoracic Surgery, , Corporate Member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Mangieri","sequence":"additional","affiliation":[{"name":"San Raffaele Hospitals EMO-GVM Centro Cuore and , Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Lauten","sequence":"additional","affiliation":[{"name":"Charit\u00e9 - Universitaetsmedizin Berlin Department of Cardiology, , Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Frerker","sequence":"additional","affiliation":[{"name":"Asklepios Klinik St. Georg, Hamburg Department of Cardiology, , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Han","family":"Yoon","sequence":"additional","affiliation":[{"name":"Cedars-Sinai Heart Institute Department of Interventional Cardiology, , Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Holzamer","sequence":"additional","affiliation":[{"name":"University Medical Center Department of Cardiothoracic Surgery, , Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5416-165X","authenticated-orcid":false,"given":"Fabien","family":"Praz","sequence":"additional","affiliation":[{"name":"University Hospital Bern Department of Cardiology, , Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole","family":"De Backer","sequence":"additional","affiliation":[{"name":"University of Copenhagen The Heart Center, Rigshospitalet, , Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Toggweiler","sequence":"additional","affiliation":[{"name":"Lucerner Kantonsspital, Lucerne Heart Center Lucerne, , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Blumenstein","sequence":"additional","affiliation":[{"name":"St. Johannes Hospital Department of Cardiology, , Dortmund, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Purita","sequence":"additional","affiliation":[{"name":"Thoracic and Vascular Sciences, University of Padua Department of Cardiac, , Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Tarantini","sequence":"additional","affiliation":[{"name":"Thoracic and Vascular Sciences, University of Padua Department of Cardiac, , Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Thilo","sequence":"additional","affiliation":[{"name":"Klinikum Augsburg, Herzzentrum , Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Wolf","sequence":"additional","affiliation":[{"name":"Elisabeth-Hospital Essen Department of Cardiology and Angiology, , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Husser","sequence":"additional","affiliation":[{"name":"St. Johannes Hospital Department of Cardiology, , Dortmund, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Costanza","family":"Pellegrini","sequence":"additional","affiliation":[{"name":"Deutsches Herzzentrum M\u00fcnchen, Technical University of Munich Klinik f\u00fcr Herz- und Kreislauferkrankungen, , Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christof","family":"Burgdorf","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center Bad Bevensen Department of Cardiology, , Bad Bevensen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa Ana Hernandez","family":"Antolin","sequence":"additional","affiliation":[{"name":"University Hospital Ramon Y Cajal-Madrid , Interventional Cardiology Unit, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor A Jim\u00e9nez","family":"D\u00edaz","sequence":"additional","affiliation":[{"name":"University Hospital of Vigo Hospital Alvaro Cunqueiro, Interventional Cardiology Unit, Department of Cardiology, , Vigo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Liebetrau","sequence":"additional","affiliation":[{"name":"Kerckhoff Heart Center, Department of Cardiology , Bad Nauheim, Germany"},{"name":"DZHK (German Center for Cardiovascular Research), Partner Site Rhein-Main, Frankfurt am Main, Germany"},{"name":"Justus-Liebig University of Giessen and Marburg Department of Cardiology, , Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niklas","family":"Schofer","sequence":"additional","affiliation":[{"name":"University Heart Center Department of General and Interventional Cardiology, , University Hospital Hamburg-Eppendorf (UKE), Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helge","family":"M\u00f6llmann","sequence":"additional","affiliation":[{"name":"St. Johannes Hospital Department of Cardiology, , Dortmund, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Eggebrecht","sequence":"additional","affiliation":[{"name":"CCB Department of Cardiology, Cardioangiologisches Centrum Bethanien ( ) at the AGAPLESION Bethanien Hospital, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Sondergaard","sequence":"additional","affiliation":[{"name":"University of Copenhagen The Heart Center, Rigshospitalet, , Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Walther","sequence":"additional","affiliation":[{"name":"Kerckhoff Heart Center Department of Cardiac Surgery, , Bad Nauheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8721-4068","authenticated-orcid":false,"given":"Thomas","family":"Pilgrim","sequence":"additional","affiliation":[{"name":"University of Copenhagen The Heart Center, Rigshospitalet, , 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