{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:55:46Z","timestamp":1770224146153,"version":"3.49.0"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"Supplement_L","license":[{"start":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T00:00:00Z","timestamp":1605657600000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Arrhythmogenic right ventricular cardiomyopathy is a myocardial disease generally caused by desmosomal mutations and characterized by progressive replacement of cardiomyocites with fibro-adipose tissue. In the classic form of the disease right ventricle is predominantly affected. However, biventricular and left-dominant variants have been recently recognized, leading to the new nosological definition of arrhythmogenic cardiomyopathy. The condition affects mostly young adults and athletes and is clinically characterized by ventricular arrhythmias, heart failure and sudden cardiac death. The diagnosis is based on clinical-instrumental criteria, including family history, morpho-functional and electrocardiographic abnormalities, ventricular arrhythmias and genetic defects (Task Force Criteria, 2010). The main goal in the management of patients is the prevention of sudden cardiac death, where implantable cardioverter-defibrillator is the only effective therapeutic strategy. Many arrhythmic risk factors have been described. Recently, an on-line calculator has been proposed, but it needs further validation.<\/jats:p>","DOI":"10.1093\/eurheartj\/suaa152","type":"journal-article","created":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T23:45:25Z","timestamp":1605743125000},"page":"L129-L135","source":"Crossref","is-referenced-by-count":5,"title":["Focus on arrhythmogenic right ventricular cardiomyopathy"],"prefix":"10.1093","volume":"22","author":[{"given":"Gianfranco","family":"Sinagra","sequence":"first","affiliation":[{"name":"Dipartimento Cardiotoracovascolare e Unit\u00e0 Clinico Operativa di Radiologia Diagnostica ed Interventistica; Azienda Sanitaria Universitaria Giuliano Isontina, Universit\u00e0 degli Studi di Trieste"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Cappelletto","sequence":"additional","affiliation":[{"name":"Dipartimento Cardiotoracovascolare e Unit\u00e0 Clinico Operativa di Radiologia Diagnostica ed Interventistica; Azienda Sanitaria Universitaria Giuliano Isontina, Universit\u00e0 degli Studi di Trieste"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"DE Luca","sequence":"additional","affiliation":[{"name":"Dipartimento Cardiotoracovascolare e Unit\u00e0 Clinico Operativa di Radiologia Diagnostica ed Interventistica; Azienda Sanitaria Universitaria Giuliano Isontina, Universit\u00e0 degli Studi di Trieste"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Romani","sequence":"additional","affiliation":[{"name":"Dipartimento Cardiotoracovascolare e Unit\u00e0 Clinico Operativa di Radiologia Diagnostica ed Interventistica; Azienda Sanitaria Universitaria Giuliano Isontina, Universit\u00e0 degli Studi di Trieste"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessia","family":"Paldino","sequence":"additional","affiliation":[{"name":"Dipartimento Cardiotoracovascolare e Unit\u00e0 Clinico Operativa di Radiologia Diagnostica ed Interventistica; Azienda Sanitaria Universitaria Giuliano Isontina, Universit\u00e0 degli Studi di Trieste"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata","family":"Korcova","sequence":"additional","affiliation":[{"name":"Dipartimento Cardiotoracovascolare e Unit\u00e0 Clinico Operativa di Radiologia Diagnostica ed Interventistica; Azienda Sanitaria Universitaria Giuliano Isontina, Universit\u00e0 degli Studi di Trieste"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo Dal","family":"Ferro","sequence":"additional","affiliation":[{"name":"Dipartimento Cardiotoracovascolare e Unit\u00e0 Clinico Operativa di Radiologia Diagnostica ed Interventistica; Azienda Sanitaria Universitaria Giuliano Isontina, Universit\u00e0 degli Studi di Trieste"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giancarlo","family":"Vitrella","sequence":"additional","affiliation":[{"name":"Dipartimento Cardiotoracovascolare e Unit\u00e0 Clinico Operativa di Radiologia Diagnostica ed Interventistica; Azienda Sanitaria Universitaria Giuliano Isontina, Universit\u00e0 degli Studi di Trieste"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Pagnan","sequence":"additional","affiliation":[{"name":"Dipartimento Cardiotoracovascolare e Unit\u00e0 Clinico Operativa di Radiologia Diagnostica ed Interventistica; Azienda Sanitaria Universitaria Giuliano Isontina, Universit\u00e0 degli Studi di Trieste"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Pinamonti","sequence":"additional","affiliation":[{"name":"Dipartimento Cardiotoracovascolare e Unit\u00e0 Clinico Operativa di Radiologia Diagnostica ed Interventistica; Azienda Sanitaria Universitaria Giuliano Isontina, Universit\u00e0 degli Studi di Trieste"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,11,18]]},"reference":[{"key":"2020111813464516700_suaa152-B1","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1161\/CIRCULATIONAHA.108.840827","article-title":"Diagnosis of arrhythmogenic right ventricular cardiomyopathy\/dysplasia: proposed modification of the task force criteria","volume":"121","author":"Marcus","year":"2010","journal-title":"Circulation"},{"key":"2020111813464516700_suaa152-B2","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1056\/NEJMra1509267","article-title":"Arrhythmogenic Right Ventricular Cardiomyopathy","volume":"376","author":"Corrado","year":"2017","journal-title":"N Engl J Med"},{"key":"2020111813464516700_suaa152-B3","doi-asserted-by":"crossref","first-page":"e301","DOI":"10.1016\/j.hrthm.2019.05.007","article-title":"2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy","volume":"16","author":"Towbin","year":"2019","journal-title":"Heart Rhythm"},{"key":"2020111813464516700_suaa152-B4","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1161\/CIRCULATIONAHA.118.037230","article-title":"Sudden Death and Left Ventricular Involvement in Arrhythmogenic Cardiomyopathy","volume":"139","author":"Miles","year":"2019","journal-title":"Circulation"},{"key":"2020111813464516700_suaa152-B5","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/j.jacc.2019.06.072","article-title":"Genetic Risk of Arrhythmic Phenotypes in Patients With Dilated Cardiomyopathy","volume":"74","author":"Gigli","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2020111813464516700_suaa152-B6","volume-title":"From Genetics to Clinical Management","author":"Sinagra","year":"2019"},{"key":"2020111813464516700_suaa152-B7","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1093\/eurheartj\/ehv387","article-title":"Approach to family screening in arrhythmogenic right ventricular dysplasia\/cardiomyopathy","volume":"37","author":"Te Riele","year":"2016","journal-title":"Eur Heart J"},{"key":"2020111813464516700_suaa152-B8","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.1016\/j.jacc.2016.02.062","article-title":"Etiology of Sudden Death in Sports: insights From a United Kingdom Regional Registry","volume":"67","author":"Finocchiaro","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"2020111813464516700_suaa152-B9","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/ehjci\/jew229","article-title":"Comprehensive multi-modality imaging approach in arrhythmogenic cardiomyopathy-an expert consensus document of the European Association of Cardiovascular Imaging","volume":"18","author":"Haugaa","year":"2017","journal-title":"Eur Heart J Cardiovasc Img"},{"key":"2020111813464516700_suaa152-B10","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-319-06019-4","volume-title":"Clinical Echocardiography and Other Imaging Techniques in Cardiomyopathies","author":"Pinamonti","year":"2014"},{"key":"2020111813464516700_suaa152-B11","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1016\/j.amjcard.2016.08.056","article-title":"Usefulness of combined functional assessment by cardiac magnetic resonance and tissue characterization vs. task force criteria for diagnosis of arrhythmogenic right ventricular cardiomyopathy","volume":"118","author":"Aquaro","year":"2016","journal-title":"Am J Cardiol"},{"key":"2020111813464516700_suaa152-B12","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1093\/eurheartj\/ehr040","article-title":"Prognostic predictors in arrhythmogenic right ventricular cardiomyopathy: results from a 10-year registry","volume":"32","author":"Pinamonti","year":"2011","journal-title":"Eur Heart J"},{"key":"2020111813464516700_suaa152-B13","doi-asserted-by":"crossref","first-page":"f20","DOI":"10.1093\/europace\/eux093","article-title":"Lifelong arrhythmic risk stratification in arrhythmogenic right ventricular cardiomyopathy: distribution of events and impact of periodical reassessment","volume":"20","author":"Cappelletto","year":"2018","journal-title":"Europace"},{"key":"2020111813464516700_suaa152-B14","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1161\/CIRCULATIONAHA.117.030792","article-title":"Risk Stratification in Arrhythmogenic Right Ventricular Cardiomyopathy","volume":"136","author":"Calkins","year":"2017","journal-title":"Circulation"},{"key":"2020111813464516700_suaa152-B15","doi-asserted-by":"crossref","first-page":"2753","DOI":"10.1016\/j.jacc.2020.04.023","article-title":"Prognostic Value of Magnetic Resonance Phenotype in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy","volume":"75","author":"Aquaro","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"2020111813464516700_suaa152-B16","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1093\/eurheartj\/ehz103","article-title":"A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy","volume":"40","author":"Cadrin-Tourigny","year":"2019","journal-title":"Eur Heart J"}],"container-title":["European Heart Journal Supplements"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/eurheartjsupp\/article-pdf\/22\/Supplement_L\/L129\/34386905\/suaa152.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/eurheartjsupp\/article-pdf\/22\/Supplement_L\/L129\/34386905\/suaa152.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T23:45:28Z","timestamp":1605743128000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurheartjsupp\/article\/22\/Supplement_L\/L129\/5989623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,1]]},"references-count":16,"journal-issue":{"issue":"Supplement_L","published-online":{"date-parts":[[2020,11,18]]},"published-print":{"date-parts":[[2020,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/eurheartj\/suaa152","relation":{},"ISSN":["1520-765X","1554-2815"],"issn-type":[{"value":"1520-765X","type":"print"},{"value":"1554-2815","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,11]]},"published":{"date-parts":[[2020,11,1]]}}}