{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:50:33Z","timestamp":1788349833597,"version":"build-2803163510"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"Supplement_C","license":[{"start":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T00:00:00Z","timestamp":1682467200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Patients with acute coronary syndromes (ACS) and multivessel coronary artery disease are frequently encountered during clinical practice and those patients are at higher risk of subsequent acute cardiovascular events. In patients presenting with both ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndromes, complete revascularization is associated with decreased risk of major adverse cardiovascular events. Nevertheless, the optimal timing of the intervention and treatment modality are still in discussions. Furthermore, non-culprit lesions assessment based on stenosis severity, either on visual or on functional evaluation, may not provide information about vulnerable plaques prone to thrombosis. Therefore, insights from intracoronary imaging could further identify high-risk plaque and patients at higher risk of future adverse events. This article aims to provide an overview of current guideline recommendations, envisioning future perspectives for the treatment of patients with ACS and multivessel disease.<\/jats:p>","DOI":"10.1093\/eurheartjsupp\/suad010","type":"journal-article","created":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T17:55:57Z","timestamp":1682531757000},"page":"C74-C78","source":"Crossref","is-referenced-by-count":14,"title":["Acute coronary syndromes and multivessel coronary artery disease"],"prefix":"10.1093","volume":"25","author":[{"given":"Giuseppe","family":"Zimbardo","sequence":"first","affiliation":[{"name":"Department of Cardiology, Policlinico Casilino , Via Casilina 1049, Rome 00169 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pio","family":"Cialdella","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Policlinico Casilino , Via Casilina 1049, Rome 00169 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Di Fusco","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Policlinico Casilino , Via Casilina 1049, Rome 00169 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Edward","family":"Donahue","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Policlinico Casilino , Via Casilina 1049, Rome 00169 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umberto Maria Lombardi","family":"D\u2019Aquino","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Policlinico Casilino , Via Casilina 1049, Rome 00169 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Paolucci","sequence":"additional","affiliation":[{"name":"Clinica Mediterranea , Via Orazio, 2, Napoli 80122 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia 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