{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:55:13Z","timestamp":1791996913838,"version":"4.4.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"Supplement_I","license":[{"start":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T00:00:00Z","timestamp":1702425600000},"content-version":"vor","delay-in-days":12,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Abiomed Europe GmbH"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Cardiogenic shock (CS) is a life-threatening condition characterized by a state of inadequate systemic tissue perfusion caused by cardiac dysfunction. When to implement, change, or remove the use of a temporary mechanical circulatory support (tMCS) in patients with CS is dependent on the aetiology and severity. Here, patient scenarios underlying the need to escalate, de-escalate, wean, or bridge from tMCS devices are taken into consideration by interdisciplinary heart failure and CS teams. This includes a comprehensive review of and focus on the rationale for specific device escalation and de-escalation strategies, device selection, and general management.<\/jats:p>","DOI":"10.1093\/eurheartjsupp\/suad131","type":"journal-article","created":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T15:07:45Z","timestamp":1699283265000},"page":"I32-I38","source":"Crossref","is-referenced-by-count":24,"title":["Differential utilization of Impella devices, extracorporeal membrane oxygenation, and combined therapies as escalation and de-escalation strategies"],"prefix":"10.1093","volume":"25","author":[{"given":"Alexander M","family":"Bernhardt","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart and Vascular Center , Martinistrasse 52, Hamburg 20246, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgenij","family":"Potapov","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charite Campus Virchow-Klinikum , Augustenburger 1, Berlin 13353 , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Vandenbriele","sequence":"additional","affiliation":[{"name":"Department of Cardiolovascular Sciences, KU Leuven , Herestraat 49, Leuven 3000 , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten","family":"Skurk","sequence":"additional","affiliation":[{"name":"Klinik fur Kardiologie, Angiologie and Intensivmedizin, Deutsches Herzzentrum der Charite, Campus Benjamin Franklin, Hindenburgdamn 39, Berlin 12203, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Letizia F","family":"Bertoldi","sequence":"additional","affiliation":[{"name":"Cardio Center, IRCCS Humanitas Clinical and Research Center , Via Alessandro Manzoni 56, Rozzano (MI) 20089 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Pappalardo","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Anesthesia, AO SS Antonio e Biagio e Cesare Arrigo , Via Venezia 16, Alessandria 15121 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,12,13]]},"reference":[{"key":"2023121301093174100_suad131-B1","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1093\/ehjacc\/zuab015","article-title":"Joint EAPCI\/ACVC expert consensus document on percutaneous ventricular assist devices","volume":"10","author":"Chieffo","year":"2021","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"2023121301093174100_suad131-B2","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.jacc.2020.12.054","article-title":"Managing patients with short-term mechanical circulatory support: JACC review topic of the 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Fail"},{"key":"2023121301093174100_suad131-B11","doi-asserted-by":"crossref","first-page":"E50","DOI":"10.1161\/CIR.0000000000001076","article-title":"Escalating and de-escalating temporary mechanical circulatory support in cardiogenic shock: a scientific statement from the American Heart Association","volume":"146","author":"Geller","year":"2022","journal-title":"Circulation"},{"key":"2023121301093174100_suad131-B12","doi-asserted-by":"crossref","first-page":"A35","DOI":"10.1093\/eurheartj\/suab007","article-title":"Escalation and de-escalation of mechanical circulatory support in cardiogenic shock","volume":"23","author":"Bertoldi","year":"2021","journal-title":"Eur Heart J Suppl"},{"key":"2023121301093174100_suad131-B13","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.jtcvs.2015.02.043","article-title":"Extracorporeal life support in cardiogenic shock: impact of acute versus chronic etiology on outcome","volume":"150","author":"Tarzia","year":"2015","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2023121301093174100_suad131-B14","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1002\/ejhf.668","article-title":"Concomitant implantation of Impella\u00ae on top of veno-arterial extracorporeal membrane oxygenation may improve survival of patients with cardiogenic shock","volume":"19","author":"Pappalardo","year":"2017","journal-title":"Eur J Heart Fail"},{"key":"2023121301093174100_suad131-B15","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1177\/0391398817752575","article-title":"Maximum level of mobility with axillary deployment of the Impella 5.0 is associated with improved survival","volume":"41","author":"Esposito","year":"2018","journal-title":"Int J Artif Organs"},{"key":"2023121301093174100_suad131-B16","doi-asserted-by":"crossref","first-page":"2956","DOI":"10.1016\/j.jacc.2020.10.036","article-title":"Transition from temporary to durable 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