{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T14:45:07Z","timestamp":1783694707242,"version":"3.55.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"Supplement_1","license":[{"start":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T00:00:00Z","timestamp":1739923200000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Hypertrophic cardiomyopathy (HCM) is a genetic condition primarily caused by mutations in sarcomeric proteins, leading to abnormal thickening of the left ventricular wall. Although HCM is the most common genetic cardiovascular disorder, other conditions\u2014such as cardiac amyloidosis, Fabry disease, and mitochondrial myopathies\u2014can mimic its phenotype, complicating diagnosis. Accurate differentiation between HCM and its phenocopies is crucial, as these conditions differ in treatment, prognosis, and inheritance. This paper reviews the clinical, imaging, and laboratory tools essential for diagnosing HCM and its mimics, emphasizing the role of advanced diagnostics like cardiac magnetic resonance, genetic testing, and tissue characterization in guiding personalized management strategies.<\/jats:p>","DOI":"10.1093\/eurheartjsupp\/suae099","type":"journal-article","created":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T11:17:51Z","timestamp":1739963871000},"page":"i40-i46","source":"Crossref","is-referenced-by-count":10,"title":["From thick walls to clear answers: approaches to diagnosing hypertrophic cardiomyopathy and its mimics"],"prefix":"10.1093","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4711-0891","authenticated-orcid":false,"given":"Filippo","family":"Angelini","sequence":"first","affiliation":[{"name":"Division of Cardiology, Cardiovascular and Thoracic Department, Citt\u00e0 della Salute e della Scienza , Corso Bramante 88, 10126 Turin ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7868-1852","authenticated-orcid":false,"given":"Pier Paolo","family":"Bocchino","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular and Thoracic Department, Citt\u00e0 della Salute e della Scienza , Corso Bramante 88, 10126 Turin ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2290-3126","authenticated-orcid":false,"given":"Veronica","family":"Dusi","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular and Thoracic Department, Citt\u00e0 della Salute e della Scienza , Corso Bramante 88, 10126 Turin ,","place":["Italy"]},{"name":"Department of Medical Sciences, University of Turin , Corso Achille Mario Dogliotti, 14, 10126 Turin ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Pidello","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular and Thoracic Department, Citt\u00e0 della Salute e della Scienza , Corso Bramante 88, 10126 Turin ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano Maria","family":"De Ferrari","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular and Thoracic Department, Citt\u00e0 della Salute e della Scienza , Corso Bramante 88, 10126 Turin ,","place":["Italy"]},{"name":"Department of Medical Sciences, University of Turin , Corso Achille Mario Dogliotti, 14, 10126 Turin ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Raineri","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular and Thoracic Department, Citt\u00e0 della Salute e della Scienza , Corso Bramante 88, 10126 Turin ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,2,19]]},"reference":[{"key":"2025021911173511000_suae099-B1","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1093\/eurheartj\/ehad194","article-title":"2023 ESC guidelines for the management of cardiomyopathies","volume":"44","author":"Arbelo","year":"2023","journal-title":"Eur Heart J"},{"key":"2025021911173511000_suae099-B2","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/j.cjca.2024.02.025","article-title":"The diagnostic and therapeutic implications of phenocopies and mimics of hypertrophic cardiomyopathy","volume":"40","author":"Bakalakos","year":"2024","journal-title":"Can J Cardiol"},{"key":"2025021911173511000_suae099-B3","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1093\/eurheartj\/ehs397","article-title":"Diagnostic work-up in cardiomyopathies: bridging the gap between clinical phenotypes and final diagnosis. 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