{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:32:19Z","timestamp":1787963539032,"version":"build-2784847793"},"reference-count":75,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T00:00:00Z","timestamp":1616976000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"The Shandong Key Research and Development","award":["2016GSF201046"],"award-info":[{"award-number":["2016GSF201046"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Social dysfunction is adversely associated with individuals\u2019 physical and mental quality of life. However, little is known about the status of social dysfunction and its associated factors in patients with heart failure. Our study aimed to reveal the prevalence of social dysfunction, and the associations between fatigue, dyspnoea, anxiety, depression, social connectedness, and social dysfunction in patients with heart failure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>We assessed the social dysfunction, fatigue, dyspnoea, anxiety, depression, and social connectedness using self-report questionnaires among 291 patients (64.13\u2009\u00b1\u200911.84\u2009years, 53.3% male) with heart failure. Two stepwise forward logistic regression models were employed to identify the factors associated with social dysfunction, and the area under receiver operating characteristic curve was used to calculate the variance of the associated factors accounting for social dysfunction. Of the 291 patients, 76.6% reported social dysfunction. The logistic regression model after adjusting co-variables showed that fatigue [odds ratio (OR) 4.233, 95% confidence interval (CI) 1.778\u201310.081], dyspnoea (OR 0.866, 95% CI 0.756\u20130.991), depression (OR 1.173, 95% CI 1.037\u20131.328) were positively associated with social dysfunction, whereas social connectedness (OR 0.394, 95% CI 0.203\u20130.764) was negatively associated with social dysfunction. Four factors explained 84.5% of the variance of social dysfunction in patients with heart failure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Social dysfunction is prevalent in patients with heart failure, and fatigue, dyspnoea, depression, and social connectedness are the associated factors. The findings indicate that the key to helping heart failure patients return to social life may be to attenuate fatigue, dyspnoea, and depression and to improve social connectedness.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurjcn\/zvaa027","type":"journal-article","created":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T04:13:25Z","timestamp":1609474405000},"page":"475-484","source":"Crossref","is-referenced-by-count":9,"title":["Identification of factors associated with social dysfunction in patients with heart failure"],"prefix":"10.1093","volume":"20","author":[{"given":"Lyu","family":"Wang","sequence":"first","affiliation":[{"name":"School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjie","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Gerontology, School of Humanities, Shandong Management University, Jinan, Shandong, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"An","sequence":"additional","affiliation":[{"name":"School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cancan","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuzhen","family":"Fan","sequence":"additional","affiliation":[{"name":"School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,3,29]]},"reference":[{"key":"2021070805191358300_zvaa027-B1","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/S0140-6736(17)32520-5","article-title":"Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals","volume":"391","author":"Conrad","year":"2018","journal-title":"Lancet"},{"key":"2021070805191358300_zvaa027-B2","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1161\/CIR.0000000000000659","article-title":"Heart disease and stroke statistics-2019 update: a report from the American Heart Association","volume":"139","author":"Benjamin","year":"2019","journal-title":"Circulation"},{"key":"2021070805191358300_zvaa027-B3","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.2147\/DDDT.S148949","article-title":"Burden of heart failure on patients from China: results from a cross-sectional survey","volume":"12","author":"Jackson","year":"2018","journal-title":"Drug Des Dev Ther"},{"key":"2021070805191358300_zvaa027-B4","first-page":"229","article-title":"Exploring subjective well-being in older age by using Participant-generated Word Clouds","volume":"57","author":"Douma","year":"2017","journal-title":"Gerontologist"},{"key":"2021070805191358300_zvaa027-B5","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.neubiorev.2018.09.012","article-title":"Social brain, social dysfunction and social withdrawal","volume":"97","author":"Porcelli","year":"2019","journal-title":"Neurosci Biobehav Rev"},{"key":"2021070805191358300_zvaa027-B6","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0010-440X(00)90133-0","article-title":"Assessment of social functioning in depression","volume":"41","author":"Bosc","year":"2000","journal-title":"Compr Psychiat"},{"key":"2021070805191358300_zvaa027-B7","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1080\/07399330701723830","article-title":"Psychological well-being in women with heart failure: can social roles make a difference?","volume":"29","author":"Plach","year":"2007","journal-title":"Health Care Women Int"},{"key":"2021070805191358300_zvaa027-B8","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1177\/1474515119825704","article-title":"Measuring health status and symptom burden using a web-based mHealth application in patients with heart failure","volume":"18","author":"Baik","year":"2019","journal-title":"Eur J. 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