{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T07:55:07Z","timestamp":1770882907639,"version":"3.50.1"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T00:00:00Z","timestamp":1643241600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Lower leg strength at hospital discharge is strongly associated with poor prognosis in older patients with acute decompensated heart failure (ADHF). Improving leg strength is important in acute-phase cardiac rehabilitation (CR).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>This study aimed to clarify whether a change in leg strength occurs during hospitalization of older ADHF patients receiving CR and whether it affects leg strength at discharge.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>We enrolled 247 ADHF patients who underwent CR during hospitalization. They were divided into the non-older patient group (&amp;lt;75 years; n = 142) and older patient group (\u226575 years; n = 105). Quadriceps isometric strength (QIS), body mass-corrected QIS (%BM QIS), and change in QIS during hospitalization (QIS ratio) were evaluated in all patients. Physical function in the stable phase was measured by the Performance Measure for Activities of Daily Living-8 (PMADL-8). The QIS value increased during hospitalization in the non-older patient group (30.0 \u00b1 11.1 vs. 31.6 \u00b1 10.9 kgf, P &amp;lt; 0.001) but did not increase in the older patient group (19.1 \u00b1 6.3 vs. 19.5 \u00b1 6.1 kgf, P = 0.275). Multiple regression analysis revealed that PMADL-8 significantly predicted %BM QIS at discharge in the non-older patient group (\u03b2 = \u22120.254, P = 0.004), whereas in the older patient group, QIS ratio and PMADL-8 significantly predicted %BM QIS at discharge (\u03b2 = 0.264, P = 0.008 for QIS ratio and \u03b2 = \u22120.307, P = 0.003 for PMADL-8).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Leg strength was not improved in older ADHF patients during hospitalization even if they received CR, and this affected leg strength at discharge, suggesting that careful skeletal muscle intervention should be provided during hospitalization, and patients need to continue exercise after discharge.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurjcn\/zvac004","type":"journal-article","created":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T12:08:29Z","timestamp":1642162109000},"page":"741-749","source":"Crossref","is-referenced-by-count":2,"title":["Relevant factors of leg strength at hospital discharge in patients hospitalized due to acute decompensated heart failure: multi-institutional prospective observational study"],"prefix":"10.1093","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7526-4508","authenticated-orcid":false,"given":"Shinji","family":"Nemoto","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, St. Marianna University School of Medicine Yokohama City Seibu Hospital , 1197-1 Yasashicho, Asahi-ku, Yokohama 241-0811 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Kasahara","sequence":"additional","affiliation":[{"name":"Department of Public Health, Kobe University Graduate School of Health Sciences , 7-10-2, Tomogaoka, Suma-ku, Kobe 654-0142 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7262-8903","authenticated-orcid":false,"given":"Kazuhiro P","family":"Izawa","sequence":"additional","affiliation":[{"name":"Department of Public Health, Kobe University Graduate School of Health Sciences , 7-10-2, Tomogaoka, Suma-ku, Kobe 654-0142 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, St. Marianna University School of Medicine Hospital , 2-16-1 Sugao, Miyamae-ku, Kawasaki 216-8511 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuya","family":"Yoshizawa","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Kawasaki Municipal Tama Hospital , 1-30-37 Shukugawara, Tama-ku, Kawasaki 214-8525 , 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