{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:06:12Z","timestamp":1789153572520,"version":"build-2803163510"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T00:00:00Z","timestamp":1661472000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"The National Natural Science Fund","award":["82000093"],"award-info":[{"award-number":["82000093"]}]},{"name":"Postgraduate Research & Practice Innovation Program of Jiangsu Province","award":["SJCX21_1479"],"award-info":[{"award-number":["SJCX21_1479"]}]},{"name":"Nantong Health Commission","award":["MA2021006"],"award-info":[{"award-number":["MA2021006"]}]},{"name":"Nantong Health Commission","award":["JC2020044"],"award-info":[{"award-number":["JC2020044"]}]},{"name":"Affiliated Hospital of Nantong University","award":["Tfh 2106"],"award-info":[{"award-number":["Tfh 2106"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>This study aimed to develop a nomogram model for predicting prolonged mechanical ventilation (PMV) in patients undergoing cardiovascular surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>In total, 693 patients undergoing cardiovascular surgery at an Affiliated Hospital of Nantong University between January 2018 and June 2020 were studied. Postoperative PMV was required in 147 patients (21.2%). Logistic regression analysis showed that delirium [odds ratio (OR), 3.063; 95% confidence interval (CI), 1.991\u20134.713; P\u200a&amp;lt;\u200a0.001], intraoperative blood transfusion (OR, 2.489; 95% CI, 1.565\u20133.960; P\u200a&amp;lt;\u200a0.001), obesity (OR, 2.789; 95% CI, 1.543\u20135.040; P\u200a=\u200a0.001), postoperative serum creatinine level (mmol\/L; OR, 1.012; 95% CI, 1.007\u20131.017; P\u200a&amp;lt;\u200a0.001), postoperative serum albumin level (g\/L; OR, 0.937; 95% CI, 0.902\u20130.973; P\u200a=\u200a0.001), and postoperative total bilirubin level (\u03bcmol\/L; OR, 1.020; 95% CI, 1.005\u20131.034; P\u200a=\u200a0.008) were independent risk factors for PMV. The area under the receiver operating characteristic curve for our nomogram was found to be 0.770 (95% CI, 0.727\u20130.813). The goodness-of-fit test indicated that the model fitted the data well (\u03c72\u200a=\u200a12.480, P\u200a=\u200a0.131). After the model was internally validated, the calibration plot demonstrated good performance of the nomogram, as supported by the Harrell concordance index of 0.760. Decision curve analysis demonstrated that the nomogram was clinically useful in identifying patients at risk for PMV.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>We established a new nomogram model that may provide an individual prediction of PMV. This model may provide nurses, social workers, physicians, and administrators with an accurate and objective assessment tool to identify patients at high risk for PMV after cardiovascular surgery.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurjcn\/zvac076","type":"journal-article","created":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T07:58:24Z","timestamp":1661500704000},"page":"594-601","source":"Crossref","is-referenced-by-count":11,"title":["Establishment of a nomogram for predicting prolonged mechanical ventilation in cardiovascular surgery patients"],"prefix":"10.1093","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4121-8455","authenticated-orcid":false,"given":"Yunjiao","family":"Meng","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Intensive Care Unit, Affiliated Hospital of Nantong University , No.20, Xi Si Road, Chongchuan District, Nantong City, Jiangsu Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1197-9317","authenticated-orcid":false,"given":"Haoye","family":"Gu","sequence":"additional","affiliation":[{"name":"Affiliated Nantong Hospital of Shanghai University , No. 881, Yonghe Road, Chongchuan District, Nantong City, Jiangsu Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5306-7047","authenticated-orcid":false,"given":"Xuan","family":"Qian","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Intensive Care Unit, Affiliated Hospital of Nantong University , No.20, Xi Si Road, Chongchuan District, Nantong City, Jiangsu Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5959-3213","authenticated-orcid":false,"given":"Honglei","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Intensive Care Unit, Affiliated Hospital of Nantong University , No.20, Xi Si Road, Chongchuan District, Nantong City, Jiangsu Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6202-3337","authenticated-orcid":false,"given":"Yanmei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Intensive Care Unit, Affiliated Hospital of Nantong University , No.20, Xi Si Road, Chongchuan District, Nantong City, Jiangsu Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0141-6169","authenticated-orcid":false,"given":"Peipei","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Intensive Care Unit, Affiliated Hospital of Nantong University , No.20, Xi Si Road, Chongchuan District, Nantong City, Jiangsu Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3187-1293","authenticated-orcid":false,"given":"Yanghui","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Intensive Care Unit, Affiliated Hospital of Nantong University , No.20, Xi Si Road, Chongchuan District, Nantong City, Jiangsu Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,8,26]]},"reference":[{"key":"2023090502421808300_zvac076-B1","doi-asserted-by":"crossref","first-page":"423","DOI":"10.4037\/ajcc2016165","article-title":"Quality improvement intervention to decrease prolonged mechanical ventilation after coronary artery bypass surgery","volume":"25","author":"Hefner","year":"2016","journal-title":"Am J Crit Care"},{"key":"2023090502421808300_zvac076-B2","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.jtcvs.2016.08.020","article-title":"A derived and validated score to predict prolonged mechanical ventilation in patients undergoing cardiac surgery","volume":"153","author":"Sharma","year":"2017","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2023090502421808300_zvac076-B3","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1053\/j.jvca.2021.07.016","article-title":"Development and validation of a predictive score for prolonged mechanical ventilation after cardiac surgery","volume":"36","author":"Michaud","year":"2022","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"2023090502421808300_zvac076-B4","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1378\/chest.118.6.1724","article-title":"Morbid results of prolonged intubation after coronary artery bypass surgery","volume":"118","author":"Cohen","year":"2000","journal-title":"Chest"},{"key":"2023090502421808300_zvac076-B5","doi-asserted-by":"crossref","first-page":"550","DOI":"10.4187\/respcare.04915","article-title":"Prolonged mechanical ventilation as a predictor of mortality after cardiac surgery","volume":"63","author":"Fernandez-Zamora","year":"2018","journal-title":"Respir Care"},{"key":"2023090502421808300_zvac076-B6","doi-asserted-by":"crossref","first-page":"641","DOI":"10.21037\/atm.2019.10.77","article-title":"Development and validation of prognostic nomogram for young patients with gastric cancer","volume":"7","author":"Yu","year":"2019","journal-title":"Ann Transl Med"},{"key":"2023090502421808300_zvac076-B7","doi-asserted-by":"crossref","first-page":"2709","DOI":"10.1053\/j.jvca.2019.03.009","article-title":"Development and validation of a score to identify cardiac surgery patients at high risk of prolonged mechanical ventilation","volume":"33","author":"Hessels","year":"2019","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"2023090502421808300_zvac076-B8","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1177\/0272989X06295361","article-title":"Decision curve analysis: a novel method for evaluating prediction models","volume":"26","author":"Vickers","year":"2006","journal-title":"Med Decis Making"},{"key":"2023090502421808300_zvac076-B9","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1053\/j.jvca.2017.03.036","article-title":"Predictors of prolonged mechanical ventilation in adults after acute type-a aortic dissection repair","volume":"31","author":"Jin","year":"2017","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"2023090502421808300_zvac076-B10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.psc.2017.10.001","article-title":"Delirium in the elderly","volume":"41","author":"Hshieh","year":"2018","journal-title":"Psychiatr Clin North Am"},{"key":"2023090502421808300_zvac076-B11","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1097\/00003246-200107000-00012","article-title":"Evaluation of delirium in critically ill patients: validation of the confusion assessment method for the intensive care unit (CAM-ICU)","volume":"29","author":"Ely","year":"2001","journal-title":"Crit Care Med"},{"key":"2023090502421808300_zvac076-B12","first-page":"4524","article-title":"Advances in anthropometric prediction of cardiovascular risk factors","volume":"23","author":"Li","year":"2020","journal-title":"Chin Gen Pract"},{"key":"2023090502421808300_zvac076-B13","doi-asserted-by":"crossref","first-page":"e7543","DOI":"10.1097\/MD.0000000000007543","article-title":"Development and validation of risk-stratification delirium prediction model for critically ill patients: a prospective, observational, single-center study","volume":"96","author":"Chen","year":"2017","journal-title":"Medicine (Baltimore)"},{"key":"2023090502421808300_zvac076-B14","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/EDE.0b013e3181c30fb2","article-title":"Assessing the performance of prediction models: a framework for traditional and novel measures","volume":"21","author":"Steyerberg","year":"2010","journal-title":"Epidemiology"},{"key":"2023090502421808300_zvac076-B15","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s13019-021-01496-w","article-title":"Risk factors of postoperative delirium after cardiac surgery: a meta-analysis","volume":"16","author":"Chen","year":"2021","journal-title":"J Cardiothorac Surg"},{"key":"2023090502421808300_zvac076-B16","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1053\/j.jvca.2012.09.013","article-title":"Identification of inflammatory mediators and their modulation by strategies for the management of the systemic inflammatory response during cardiac surgery","volume":"27","author":"Hall","year":"2013","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"2023090502421808300_zvac076-B17","doi-asserted-by":"crossref","first-page":"597","DOI":"10.3390\/nu10050597","article-title":"Current evidence about nutrition support in cardiac surgery patients-what do we know?","volume":"10","author":"Hill","year":"2018","journal-title":"Nutrients"},{"key":"2023090502421808300_zvac076-B18","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1177\/0148607114536735","article-title":"Impact of preoperative prealbumin on outcomes after cardiac surgery","volume":"39","author":"Yu","year":"2015","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"2023090502421808300_zvac076-B19","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/jocs.13745","article-title":"Predictive value of preoperative serum albumin levels on outcomes in patients undergoing LVAD implantation","volume":"33","author":"Critsinelis","year":"2018","journal-title":"J Card Surg"},{"key":"2023090502421808300_zvac076-B20","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1177\/0194599820923601","article-title":"Obesity as a predictor of prolonged mechanical ventilation","volume":"163","author":"Shao","year":"2020","journal-title":"Otolaryngol Head Neck Surg"},{"key":"2023090502421808300_zvac076-B21","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1097\/EJA.0b013e3283232c69","article-title":"Predictors of prolonged mechanical ventilation in a cohort of 5123 cardiac surgical patients","volume":"26","author":"Cislaghi","year":"2009","journal-title":"Eur J Anaesthesiol"},{"key":"2023090502421808300_zvac076-B22","doi-asserted-by":"crossref","first-page":"880.e1","DOI":"10.1016\/j.jcrc.2013.03.013","article-title":"Clinical model for predicting prolonged mechanical ventilation","volume":"28","author":"Clark","year":"2013","journal-title":"J Crit Care"}],"container-title":["European Journal of Cardiovascular Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eurjcn\/advance-article-pdf\/doi\/10.1093\/eurjcn\/zvac076\/45733925\/zvac076.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjcn\/article-pdf\/22\/6\/594\/51306924\/zvac076.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjcn\/article-pdf\/22\/6\/594\/51306924\/zvac076.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T02:42:59Z","timestamp":1693881779000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurjcn\/article\/22\/6\/594\/6676416"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,26]]},"references-count":22,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2022,8,26]]},"published-print":{"date-parts":[[2023,9,5]]}},"URL":"https:\/\/doi.org\/10.1093\/eurjcn\/zvac076","relation":{},"ISSN":["1474-5151","1873-1953"],"issn-type":[{"value":"1474-5151","type":"print"},{"value":"1873-1953","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,8]]},"published":{"date-parts":[[2022,8,26]]}}}