{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:47:58Z","timestamp":1777495678571,"version":"3.51.4"},"reference-count":54,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T00:00:00Z","timestamp":1718668800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Many people diagnosed with atrial fibrillation (AF) may lack awareness of AF and anticoagulants. The purpose of this study is to investigate the effects of intensive, targeted education by pharmacists on anticoagulant patients with AF.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Three hundred seventy-six AF patients were randomly assigned to receive standard care or pharmacist education. Follow-up is scheduled after 1, 3, 6, and 12 months. Pharmacists provided intensive education on knowledge deficits revealed by the Jessa Atrial fibrillation Knowledge Questionnaire (JAKQ) during each visit. Patients also completed two questionnaires to assess their medication adherence and satisfaction. Clinical outcomes were recorded during follow-up. Three hundred sixty-one patients completed follow-up. Baseline scores on the JAKQ were similar in the education group (median: 31.3%) and the standard care group (median: 31.3%) (P = 0.911). Over time, the knowledge score of the education group increased significantly (1 month: 68.8%, 3 months: 81.3%; P &amp;lt; 0.001), while there was no significant improvement in the standard care group (1 month: 37.5%, 3 months: 37.5%; P = 0.314). Adherence scores improved significantly over time in the education group (P &amp;lt; 0.001) but not in the standard care group (P = 0.101). Compared with standard care, pharmacist education was associated with a significantly lower risk of bleeding (P = 0.034).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Given the knowledge deficiency of AF patients in China, standardized patient education should be a part of their daily care. Pharmacist-led education intervention can significantly improve the disease-related knowledge, medication adherence, and drug treatment satisfaction of AF patients while significantly reducing the risk of bleeding.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Registration<\/jats:title>\n                  <jats:p>ChiCTR1900024455.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurjcn\/zvae092","type":"journal-article","created":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T17:37:58Z","timestamp":1718732278000},"page":"935-944","source":"Crossref","is-referenced-by-count":6,"title":["Effects of intensive, targeted education by pharmacists on anticoagulant patients with atrial fibrillation: a multicentre randomized controlled trial from China"],"prefix":"10.1093","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1088-9408","authenticated-orcid":false,"given":"Wenlin","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University , #18 Daoshan Road, Fuzhou 350001 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9571-0862","authenticated-orcid":false,"given":"Tingting","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Longgang Distract People\u2019s Hospital of Shenzhen & The Third Affiliated Hospital (Provisional) of Chinese University of Hong Kong (Shenzhen) , Shenzhen 518172 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5779-1972","authenticated-orcid":false,"given":"Jiana","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University , #18 Daoshan Road, Fuzhou 350001 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1512-0038","authenticated-orcid":false,"given":"Meina","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Fujian Medical University Union Hospital , Fuzhou 350001 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The Second Affiliated Hospital of Chongqing Medical University , Chongqing ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3462-9929","authenticated-orcid":false,"given":"Sha","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The Second Affiliated Hospital of Chongqing Medical University , Chongqing ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9228-5163","authenticated-orcid":false,"given":"Hengfen","family":"Dai","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Affiliated Fuzhou First Hospital of Fujian Medical University , Fuzhou ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0994-9317","authenticated-orcid":false,"given":"Wei","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Xinyang Central Hospital, Xinyang Hospital Affiliated to Zhengzhou University , Xinyang ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0525-8138","authenticated-orcid":false,"given":"Pei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Affiliated Hospital of Jining Medical University , Jining ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7135-7160","authenticated-orcid":false,"given":"Meijuan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, First Hospital of Shanxi Medical University , Taiyuan, Shanxi 030001 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9351-5282","authenticated-orcid":false,"given":"Li","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Guizhou Provincial People\u2019s Hospital , Guiyang ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7268-5317","authenticated-orcid":false,"given":"Feilong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Fujian Medical University Union Hospital , Fuzhou ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3386-0944","authenticated-orcid":false,"given":"Sijie","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University , #18 Daoshan Road, Fuzhou 350001 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5629-0348","authenticated-orcid":false,"given":"Jinhua","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University , #18 Daoshan Road, Fuzhou 350001 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,6,18]]},"reference":[{"key":"2024121608055968500_zvae092-B1","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1093\/eurheartj\/ehu028","article-title":"Early management of atrial fibrillation to prevent cardiovascular complications","volume":"35","author":"Nattel","year":"2014","journal-title":"Eur Heart J"},{"key":"2024121608055968500_zvae092-B2","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jacc.2014.03.022","article-title":"2014 AHA\/ACC\/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm 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