{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T16:28:17Z","timestamp":1754152097638,"version":"3.41.2"},"reference-count":51,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T00:00:00Z","timestamp":1741996800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Swedish National Science Council","award":["K2013-69X-22302-01-3","2016-01390"],"award-info":[{"award-number":["K2013-69X-22302-01-3","2016-01390"]}]},{"name":"Swedish Research Council for Health","award":["2014-4100"],"award-info":[{"award-number":["2014-4100"]}]},{"DOI":"10.13039\/100018870","name":"Swedish Heart and Lung Association","doi-asserted-by":"publisher","award":["E085\/12"],"award-info":[{"award-number":["E085\/12"]}],"id":[{"id":"10.13039\/100018870","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003793","name":"Swedish Heart and Lung Foundation","doi-asserted-by":"publisher","award":["20130340","20160439"],"award-info":[{"award-number":["20130340","20160439"]}],"id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009107","name":"V\u00e5rdal Foundation","doi-asserted-by":"publisher","award":["2014-0018"],"award-info":[{"award-number":["2014-0018"]}],"id":[{"id":"10.13039\/100009107","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010805","name":"Medical Research Council of Southeast Sweden","doi-asserted-by":"publisher","award":["FORSS 474681"],"award-info":[{"award-number":["FORSS 474681"]}],"id":[{"id":"10.13039\/100010805","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Patients with heart failure (HF) can experience acute deterioration in symptoms of shortness of breath (SoB) and fatigue that often lead to hospitalizations. The purpose of the study was to perform a trend analysis over 12 weeks to understand the association between the intensity of HF symptoms (SoB and fatigue) and well-being in patients with HF.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>This longitudinal study used data from the HF-Wii study with daily reporting of SoB, fatigue, and well-being using a visual analogue (1\u201310) scale. The analysis included daily trending of symptoms and well-being. Overall sample means and correlations between symptoms and well-being were analysed. A subgroup of participants with high-symptom intensity (reporting \u22655 for SoB and\/or fatigue for at least 21 days) was created to highlight the profiles of participants with a higher symptom burden. Group differences were analysed using a t-test. A total of 141 participants (age 67.6 \u00b1 11 years; males 67%; New York Heart Association Class II 65%) with complete 12 weeks of daily data were identified. Symptom intensity experienced by the overall sample was 3.48 \u00b1 2.37 for SoB and 3.59 \u00b1 2.37 for fatigue. Overall well-being was 6.17 \u00b1 1.86. Significant differences (P &amp;lt; 0.001) were found between the high-symptom intensity (n = 29) and low-symptom intensity (n = 121) groups for SoB, fatigue, and well-being. The high-symptom intensity group consisted of a larger proportion of participants with chronic obstructive pulmonary disease, peripheral vascular disease, and cancer.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Daily symptoms of SoB and fatigue experienced by patients with HF are directly correlated with overall daily well-being.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurjcn\/zvaf038","type":"journal-article","created":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T03:42:15Z","timestamp":1742010135000},"page":"786-793","source":"Crossref","is-referenced-by-count":1,"title":["Shortness of breath, fatigue, and well-being in patients with heart failure: a daily trend analysis over 12 weeks"],"prefix":"10.1093","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3648-9843","authenticated-orcid":false,"given":"Pallav","family":"Deka","sequence":"first","affiliation":[{"name":"College of Nursing, Michigan State University , 1355 Bogue St, East Lansing, MI 48824 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dola","family":"Pathak","sequence":"additional","affiliation":[{"name":"College of Nursing, Michigan State University , 1355 Bogue St, East Lansing, MI 48824 ,","place":["USA"]},{"name":"Department of Statistics and Probability, Michigan State University , 619 Red Cedar Road Wells, East Lansing, MI 48824, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martje H L","family":"van der Wal","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Sciences, University Medical Center Groningen, University of Groningen , Hanzeplein 1, 9713 GZ Groningen ,","place":["The Netherlands"]},{"name":"Department of Health, Medicine and Caring Sciences, Link\u00f6ping University , Campus Norrk\u00f6ping, K\u00e5kenhus, Room 6614, 581 83 Link\u00f6ping ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Str\u00f6mberg","sequence":"additional","affiliation":[{"name":"Department of Health, Medicine and Caring Sciences, Link\u00f6ping University , Campus Norrk\u00f6ping, K\u00e5kenhus, Room 6614, 581 83 Link\u00f6ping ,","place":["Sweden"]},{"name":"Department of Cardiology, Link\u00f6ping University , 581 83 Link\u00f6ping ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4197-4026","authenticated-orcid":false,"given":"Tiny","family":"Jaarsma","sequence":"additional","affiliation":[{"name":"Department of Health, Medicine and Caring Sciences, Link\u00f6ping University , Campus Norrk\u00f6ping, K\u00e5kenhus, Room 6614, 581 83 Link\u00f6ping ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7493-0353","authenticated-orcid":false,"given":"Leonie","family":"Klompstra","sequence":"additional","affiliation":[{"name":"Department of Health, Medicine and Caring Sciences, Link\u00f6ping University , Campus Norrk\u00f6ping, K\u00e5kenhus, Room 6614, 581 83 Link\u00f6ping ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,3,15]]},"reference":[{"key":"2025072111523776200_zvaf038-B1","doi-asserted-by":"crossref","first-page":"3272","DOI":"10.1093\/cvr\/cvac013","article-title":"Global burden of heart failure: a comprehensive and updated review of epidemiology","volume":"118","author":"Savarese","year":"2022","journal-title":"Cardiovasc Res"},{"key":"2025072111523776200_zvaf038-B2","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.jacc.2012.12.038","article-title":"Heart failure\u2013associated hospitalizations in the United States","volume":"61","author":"Blecker","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"2025072111523776200_zvaf038-B3","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1007\/s40273-020-00952-0","article-title":"A systematic review of medical costs associated with heart failure in the USA (2014\u20132020)","volume":"38","author":"Urbich","year":"2020","journal-title":"Pharmacoeconomics"},{"key":"2025072111523776200_zvaf038-B4","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s10741-012-9324-0","article-title":"Unraveling new mechanisms of exercise intolerance in chronic heart failure. 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