{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T05:35:18Z","timestamp":1793424918028,"version":"4.5.0"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001349","name":"National Medical Research Council Health Services Research","doi-asserted-by":"publisher","award":["HSRGOC18may-0002"],"award-info":[{"award-number":["HSRGOC18may-0002"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>To evaluate the feasibility and effectiveness of an integrated-cardiac rehabilitation programme employing smartphone technology (I-CREST) for patients post-acute myocardial infarction (AMI) compared with a centre-based cardiac rehabilitation (CBCR) programme.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>A two-arm parallel pilot randomized controlled trial was conducted with 50 post-AMI patients recruited from a tertiary hospital in Singapore. Participants were randomly allocated to either the I-CREST or the CBCR group. Data were collected at four time points: baseline, post-intervention (6 weeks), at 3 and 6 months. An intention-to-treat approach was adopted for data analysis. Out of 2825 patients screened over 20 months, 171 (6.05%) were eligible, and 50 patients were enrolled. Pre-specified success criteria for feasibility were achieved regarding engagement, with a high rate of participation in weekly telephone calls (95.8%), and intervention safety was confirmed. However, the pre-specified success criteria for feasibility related to recruitment and engagement with weekly educational content were not met. In terms of effectiveness, I-CREST demonstrated significantly higher completion rates (84 vs. 40%; P = 0.001) and better 6-minute walk test results at the 6-week time point (530.8 vs. 480.2\u2005m; P = 0.017) compared with CBCR.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>This pilot study demonstrated the feasibility of the I-CREST programme, although recruitment methods require refinement. I-CREST showed promise as an effective alternative to CBCR, with fewer resources required. A full-scale study is recommended to confirm these findings statistically.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Registration<\/jats:title>\n                  <jats:p>ClinicalTrials.gov: NCT05270993.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurjcn\/zvaf053","type":"journal-article","created":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T07:32:12Z","timestamp":1743406332000},"page":"959-970","source":"Crossref","is-referenced-by-count":11,"title":["Feasibility and effectiveness of an integrative cardiac rehabilitation employing smartphone technology (I-CREST): a pilot randomized controlled trial"],"prefix":"10.1093","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9576-7607","authenticated-orcid":false,"given":"Hadassah Joann","family":"Ramachandran","sequence":"first","affiliation":[{"name":"Health and Social Sciences, Singapore Institute of Technology , 1 Punggol Coast Road, Level 7, Kwek Leng Beng University Tower E1, Singapore 828608 ,","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2462-6257","authenticated-orcid":false,"given":"Tee Joo","family":"Yeo","sequence":"additional","affiliation":[{"name":"National University Heart Centre Singapore, National University Hospital , 5 Lower Kent Ridge Road, Singapore 119074 ,","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7076-424X","authenticated-orcid":false,"given":"Chuen Wei Alvin","family":"Seah","sequence":"additional","affiliation":[{"name":"Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore , 14 Medical Drive, Level 5 Centre for Translational Medicine, Singapore 117599 ,","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7893-7663","authenticated-orcid":false,"given":"Tin Mei","family":"Yeo","sequence":"additional","affiliation":[{"name":"Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore , 14 Medical Drive, Level 5 Centre for Translational Medicine, Singapore 117599 ,","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5200-5079","authenticated-orcid":false,"given":"Matthew Chin Heng","family":"Chua","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Yong Loo Lin School of Medicine, National University of Singapore, IE Kent Ridge Road, Singapore 119228 ,","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1711-478X","authenticated-orcid":false,"given":"Qamaruzaman","family":"Syed Gani","sequence":"additional","affiliation":[{"name":"Rehabilitation Department, National University Hospital, National University Health System , 5 Lower Kent Ridge Road, Singapore 119074 ,","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiying Serene","family":"Lim","sequence":"additional","affiliation":[{"name":"Rehabilitation Department, National University Hospital, National University Health System , 5 Lower Kent Ridge Road, Singapore 119074 ,","place":["Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuet Ming","family":"Lai","sequence":"additional","affiliation":[{"name":"National University Heart Centre Singapore, National University Hospital , 5 Lower Kent Ridge Road, Singapore 119074 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