{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:48:29Z","timestamp":1791352109191,"version":"4.3.1"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005039","name":"Leiden University Medical Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005039","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005035","name":"Biotronik","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005035","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016242","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016242","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Abbott Medical Nederland BV"},{"DOI":"10.13039\/100006520","name":"Edwards Lifesciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006520","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000046","name":"Abbott","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000046","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008497","name":"Boston Scientific","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016304","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016304","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study aims to evaluate the diagnostic accuracy and operational workload of the Triage-HF\u2122 algorithm when integrated into a structured heart failure (HF) clinic workflow in real-world clinical practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We conducted a single-centre, prospective, real-world cohort study in a tertiary HF centre. Consecutive adult patients with HF carrying a Triage-HF\u2122-enabled cardiac implantable electronic device were followed within an alert-guided care pathway between January 2023 and August 2025. High-risk Heart Failure Risk Score alerts were considered actionable.<\/jats:p>\n                    <jats:p>A total of 180 patients were included (230 patient-years follow-up, mean age 67.5 years, 77.2% male, 48.9% ischaemic cardiomyopathy). Overall, 102 high-risk alerts occurred: 64 true positives (58 HF-related and 6 non-HF but clinically meaningful), 27 false positives, and 20 false negatives. Sensitivity was 82% (95% confidence interval (CI) 70\u201392%), specificity 91% (87\u201394%), positive predictive value 72% (60\u201381%), and negative predictive value 93% (90\u201396%). The average alert rate was 0.44 per patient-year, with an unexplained alert rate of 0.10 per patient-year. Most true-positive alerts (80%) were managed ambulatory, while 19% resulted in hospitalization. Median time to first intervention was 2 days [interquartile range (IQR) 1\u20134]. All alerts were driven by multisensor input, most commonly thoracic impedance combined with patient activity. The total estimated workload amounted to 70.3 h, corresponding to 306 h per 1000 patient-years (\u223c0.20 full-time equivalent).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Within a standardized HF care pathway, Triage-HF\u2122 demonstrated good sensitivity and high specificity and negative predictive value while imposing a modest staffing burden. These findings support the feasibility of integrating Triage-HF\u2122 into routine, proactive HF management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurjcn\/zvag082","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T12:43:43Z","timestamp":1774615423000},"page":"1185-1194","source":"Crossref","is-referenced-by-count":2,"title":["Efficacy and workload implications of the Triage-HF\u2122 algorithm in a nurse- and allied professional-led heart failure care pathway"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3786-6222","authenticated-orcid":false,"given":"Bert A C","family":"Zwaenepoel","sequence":"first","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Center , Albinusdreef 2, 2333 ZA Leiden ,","place":["The Netherlands"]},{"name":"Department of Cardiology, Algemeen Ziekenhuis Delta , Deltalaan 1, 8800 Roeselare 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University Medical Center , Albinusdreef 2, 2333 ZA Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3882-9941","authenticated-orcid":false,"given":"Lieselot","family":"van Erven","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Center , Albinusdreef 2, 2333 ZA Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J Wouter","family":"Jukema","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Center , Albinusdreef 2, 2333 ZA Leiden ,","place":["The Netherlands"]},{"name":"Netherlands Heart Institute , Moreelsepark 1, 3511 EP Utrecht ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9312-2338","authenticated-orcid":false,"given":"Anastasia 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