{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:12:11Z","timestamp":1791270731402,"version":"4.1.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2010,1,18]],"date-time":"2010-01-18T00:00:00Z","timestamp":1263772800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This article presents findings and a commentary on late-breaking trials presented during the meeting of the Heart Failure Society of America in September 2009. Unpublished reports should be considered as preliminary, since analyses may change in the final publication. The FAST trial showed somewhat better performance of intrathoracic impedance for prediction of deterioration in patients with heart failure (HF) when compared with daily weighing. The IMPROVE-HF study reported the benefits of education on the management of patients with systolic HF. Galectin-3 appeared a useful method for improving risk stratification of patients with chronic HF in a substudy of the COACH trial. A nuclear substudy of the HF-ACTION trial failed to demonstrate that resting myocardial perfusion imaging, a measure of myocardial scar and viability, was clinically useful. A small randomized controlled trial (DAD-HF) suggested that the use of low-dose dopamine in patients with acutely decompensated HF was associated with less deterioration in renal function and less hypokalaemia. The MARVEL-1 trial raises further concerns about the safety of myoblast transplantation in ischaemic HF.<\/jats:p>","DOI":"10.1093\/eurjhf\/hfp185","type":"journal-article","created":{"date-parts":[[2009,12,30]],"date-time":"2009-12-30T20:43:48Z","timestamp":1262205828000},"page":"193-196","source":"Crossref","is-referenced-by-count":18,"title":["Clinical Trials Update from the Heart Failure Society of America Meeting 2009: FAST, IMPROVE-HF, COACH Galectin-3 Substudy, HF-ACTION Nuclear Substudy, DAD-HF, and MARVEL-1"],"prefix":"10.1093","volume":"12","author":[{"given":"Mitja","family":"Lainscak","sequence":"first","affiliation":[{"name":"Division of Cardiology, University Clinic of Respiratory and Allergic Diseases Golnik , Golnik 36, SI-4204, Golnik ,","place":["Slovenia"]},{"name":"Applied Cachexia Research, Department of Cardiology , Charit\u00e9, Campus Virchow Clinic, Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison P.","family":"Coletta","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hull York Medical School, University of Hull, Castle Hill Hospital , Cottingham, Kingston-upon-Hull, HU16 5JQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasser","family":"Sherwi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hull York Medical School, University of Hull, Castle Hill Hospital , Cottingham, Kingston-upon-Hull, HU16 5JQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John G.F.","family":"Cleland","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hull York Medical School, University of Hull, Castle Hill Hospital , Cottingham, Kingston-upon-Hull, HU16 5JQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2010,1,18]]},"reference":[{"key":"2026020203364267900_ejhfhfp185-bib-0001","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.ejheart.2006.03.002","article-title":"Correlation between serial measurements of N-terminal pro brain natriuretic peptide and ambulatory cardiac filling pressures in outpatients with chronic heart failure","volume":"8","author":"Braunschweig","year":"2006","journal-title":"Eur J Heart Fail"},{"key":"2026020203364267900_ejhfhfp185-bib-0002","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.ejheart.2005.11.014","article-title":"Cardiac resynchronisation for patients with heart failure due to left ventricular systolic dysfunction\u2014a systematic review and meta-analysis","volume":"8","author":"Freemantle","year":"2006","journal-title":"Eur J Heart Fail"},{"key":"2026020203364267900_ejhfhfp185-bib-0003","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1093\/eurjhf\/hfp033","article-title":"Predicting hospitalization due to worsening heart failure using daily weight measurement: analysis of the Trans-European Network-Home-Care Management System (TEN-HMS) study","volume":"11","author":"Zhang","year":"2009","journal-title":"Eur J Heart Fail"},{"key":"2026020203364267900_ejhfhfp185-bib-0004","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/j.ejheart.2007.08.001","article-title":"Recall of lifestyle advice in patients recently hospitalised with heart failure: a EuroHeart Failure Survey analysis","volume":"9","author":"Lainscak","year":"2007","journal-title":"Eur J Heart Fail"},{"key":"2026020203364267900_ejhfhfp185-bib-0005","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.ejheart.2008.06.016","article-title":"Can monitoring of intrathoracic impedance reduce morbidity and mortality in patients with chronic heart failure? Rationale and design of the Diagnostic Outcome Trial in Heart Failure (DOT-HF)","volume":"10","author":"Braunschweig","year":"2008","journal-title":"Eur J Heart Fail"},{"key":"2026020203364267900_ejhfhfp185-bib-0006","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.ejheart.2008.08.005","article-title":"ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2008","volume":"10","author":"Dickstein","year":"2008","journal-title":"Eur J Heart Fail"},{"key":"2026020203364267900_ejhfhfp185-bib-0007","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/S0195-668X(02)00823-0","article-title":"The EuroHeart Failure survey programme\u2014a survey on the quality of care among patients with heart failure in Europe; part 1: patient characteristics and diagnosis","volume":"24","author":"Cleland","year":"2003","journal-title":"Eur Heart J"},{"key":"2026020203364267900_ejhfhfp185-bib-0008","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.ijcard.2007.08.001","article-title":"Treatment of chronic heart failure with carvedilol in daily practice: the SATELLITE survey experience","volume":"122","author":"Lainscak","year":"2007","journal-title":"Int J Cardiol"},{"key":"2026020203364267900_ejhfhfp185-bib-0009","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1093\/eurjhf\/hfn005","article-title":"Improvement in the management of chronic heart failure since the publication of the updated guidelines of the European Society of Cardiology. The Impact-Reco Programme","volume":"11","author":"de Groote","year":"2009","journal-title":"Eur J Heart Fail"},{"key":"2026020203364267900_ejhfhfp185-bib-0010","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1093\/eurheartj\/ehi251","article-title":"Adherence to guidelines is a predictor of outcome in chronic heart failure: the MAHLER survey","volume":"26","author":"Komajda","year":"2005","journal-title":"Eur Heart J"},{"key":"2026020203364267900_ejhfhfp185-bib-0011","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1016\/S0140-6736(05)67760-4","article-title":"Adherence to candesartan and placebo and outcomes in chronic heart failure in the CHARM programme: double-blind, randomised, controlled trial","volume":"366","author":"Granger","year":"2005","journal-title":"Lancet"},{"key":"2026020203364267900_ejhfhfp185-bib-0012","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.ahj.2007.03.030","article-title":"Improving the use of evidence-based heart failure therapies in the outpatient setting: the IMPROVE HF performance improvement registry","volume":"154","author":"Fonarow","year":"2007","journal-title":"Am Heart J"},{"key":"2026020203364267900_ejhfhfp185-bib-0013"},{"key":"2026020203364267900_ejhfhfp185-bib-0014","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.ijcard.2008.11.149","article-title":"Natriuretic peptides and other biomarkers in chronic heart failure: From BNP, NT-proBNP, and MR-proANP to routine biochemical markers","volume":"132","author":"Lainscak","year":"2009","journal-title":"Int J Cardiol"},{"key":"2026020203364267900_ejhfhfp185-bib-0015","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1093\/eurjhf\/hfp097","article-title":"Galectin-3: a novel mediator of heart failure development and progression","volume":"11","author":"De Boer","year":"2009","journal-title":"Eur J Heart Fail"},{"key":"2026020203364267900_ejhfhfp185-bib-0016","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.ejheart.2003.09.010","article-title":"Design and methodology of the COACH study: a multicenter randomised Coordinating study evaluating Outcomes of Advising and Counselling in Heart Failure","volume":"6","author":"Jaarsma","year":"2004","journal-title":"Eur J Heart Fail"},{"key":"2026020203364267900_ejhfhfp185-bib-0017","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1001\/archinternmed.2007.83","article-title":"Effect of moderate or intensive disease management program on outcome in patients with heart failure: Coordinating Study on Outcomes of Advising and Counselling in Heart Failure (COACH)","volume":"168","author":"Jaarsma","year":"2008","journal-title":"Arch Intern Med"},{"key":"2026020203364267900_ejhfhfp185-bib-0018","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.healun.2008.02.018","article-title":"Plasma biomarkers of myocardial fibrosis and remodeling in terminal heart failure patients supported by mechanical circulatory support devices","volume":"27","author":"Milting","year":"2008","journal-title":"J Heart Lung Transplant"},{"key":"2026020203364267900_ejhfhfp185-bib-0019","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0140-6736(03)13801-9","article-title":"Myocardial viability as a determinant of the ejection fraction response to carvedilol in patients with heart failure (CHRISTMAS trial) randomised controlled trial","volume":"362","author":"Cleland","year":"2003","journal-title":"Lancet"},{"key":"2026020203364267900_ejhfhfp185-bib-0020","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1001\/jama.2009.454","article-title":"Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial","volume":"301","author":"O'Connor","year":"2009","journal-title":"JAMA"},{"key":"2026020203364267900_ejhfhfp185-bib-0021","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.ejheart.2008.07.006","article-title":"Clinical trials update from Heart Rhythm 2008 and Heart Failure 2008: ATHENA, URGENT, INH study, HEART and CK-1827452","volume":"10","author":"Coletta","year":"2008","journal-title":"Eur J Heart Fail"},{"key":"2026020203364267900_ejhfhfp185-bib-0022","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.ejheart.2008.01.011","article-title":"Worsening renal function in patients hospitalised for acute heart failure: clinical implications and prognostic significance","volume":"10","author":"Metra","year":"2008","journal-title":"Eur J Heart Fail"},{"issue":"Abstract Suppl.","key":"2026020203364267900_ejhfhfp185-bib-0023","first-page":"139","article-title":"The effect of transient changes in laboratory parameters on distant mortality of patients hospitalized for heart failure","volume":"30","author":"Kaminski","year":"2009","journal-title":"Eur Heart J"},{"key":"2026020203364267900_ejhfhfp185-bib-0024","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1093\/eurjhf\/hfp162","article-title":"Clinical trials update from the European Society of Cardiology Meeting 2009: AAA, RELY, PROTECT, ACTIVE I, European CRT survey, German pre-SCD II registry and MADIT-CRT","volume":"11","author":"Cleland","year":"2009","journal-title":"Eur J Heart Fail"},{"key":"2026020203364267900_ejhfhfp185-bib-0025","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1007\/s00134-002-1346-y","article-title":"Low-dose dopamine: a systematic review","volume":"28","author":"Marik","year":"2002","journal-title":"Intensive Care Med"},{"key":"2026020203364267900_ejhfhfp185-bib-0026","doi-asserted-by":"crossref","first-page":"510","DOI":"10.7326\/0003-4819-142-7-200504050-00010","article-title":"Meta-analysis: low-dose dopamine increases urine output but does not prevent renal dysfunction or death","volume":"142","author":"Friedrich","year":"2005","journal-title":"Ann Intern Med"},{"key":"2026020203364267900_ejhfhfp185-bib-0027","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1161\/CIRCULATIONAHA.107.737106","article-title":"Renal vasodilatory action of dopamine in patients with heart failure: magnitude of effect and site of action","volume":"117","author":"Elkayam","year":"2008","journal-title":"Circulation"},{"key":"2026020203364267900_ejhfhfp185-bib-0028","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1161\/CIRCULATIONAHA.107.734103","article-title":"The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: first randomized placebo-controlled study of myoblast transplantation","volume":"117","author":"Menasch\u00e9","year":"2008","journal-title":"Circulation"},{"key":"2026020203364267900_ejhfhfp185-bib-0029","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1161\/CIRCULATIONAHA.108.812693","article-title":"Stem cell therapy for heart failure: are arrhythmias a real safety concern?","volume":"119","author":"Menasch\u00e9","year":"2009","journal-title":"Circulation"},{"key":"2026020203364267900_ejhfhfp185-bib-0030","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1056\/NEJMoa043399","article-title":"Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure","volume":"352","author":"Bardy","year":"2005","journal-title":"N Engl J Med"}],"container-title":["European Journal of Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1093%2Feurjhf%2Fhfp185","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1093%2Feurjhf%2Fhfp185","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1093\/eurjhf\/hfp185","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1093\/eurjhf\/hfp185","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/eurjhf\/article-pdf\/12\/2\/193\/66523054\/eurjhf_12_2_193.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjhf\/article-pdf\/12\/2\/193\/66523054\/eurjhf_12_2_193.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T08:36:53Z","timestamp":1770021413000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurjhf\/article\/12\/2\/193\/8435996"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,18]]},"references-count":30,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2010,1,18]]},"published-print":{"date-parts":[[2010,2,1]]}},"URL":"https:\/\/doi.org\/10.1093\/eurjhf\/hfp185","relation":{},"ISSN":["1388-9842","1879-0844"],"issn-type":[{"value":"1388-9842","type":"print"},{"value":"1879-0844","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2010,2]]},"published":{"date-parts":[[2010,1,18]]}}}