{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T04:13:20Z","timestamp":1771906400668,"version":"3.50.1"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This case describes a middle-aged patient with normal ejection fraction (64%) and significant dyspnoea which could not be explained by results from routine examinations. A pressure\u2013volume loop analysis revealed severe left ventricular (LV) dyssynchrony to be the underlying mechanism of heart failure. The patient underwent implantation of a biventricular pacemaker. Cardiac resynchronization therapy (CRT) was associated with an immediate reduction in LV dyssynchrony from 32 to 13%, decrease in LV end-diastolic pressure from 19 to 8 mmHg, and increased exercise tolerance during follow-up. Thus, CRT may be considered a causal therapy in selected patients with heart failure and preserved ejection fraction.<\/jats:p>","DOI":"10.1093\/eurjhf\/hfq068","type":"journal-article","created":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T20:13:27Z","timestamp":1272744807000},"page":"634-636","source":"Crossref","is-referenced-by-count":22,"title":["Cardiac Resynchronization Therapy for the Causal Treatment of Heart Failure with Preserved Ejection Fraction: Insight from a Pressure\u2013Volume Loop Analysis"],"prefix":"10.1093","volume":"12","author":[{"given":"Martin","family":"Penicka","sequence":"first","affiliation":[{"name":"Cardiovascular Center Aalst , Moorselbaan 164, Aalst ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viktor","family":"Kocka","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiocenter, 3rd Faculty of Medicine Charles University, University Hospital Kralovske Vinohrady Prague , Prague ,","place":["Czech Republic"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dalibor","family":"Herman","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiocenter, 3rd Faculty of Medicine Charles University, University Hospital Kralovske Vinohrady Prague , Prague ,","place":["Czech Republic"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena","family":"Trakalova","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiocenter, 3rd Faculty of Medicine Charles University, University Hospital Kralovske Vinohrady Prague , Prague ,","place":["Czech Republic"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Herold","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiocenter, 3rd Faculty of Medicine Charles University, University Hospital Kralovske Vinohrady Prague , Prague ,","place":["Czech Republic"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2014,1,13]]},"reference":[{"key":"2026020203341853100_ejhfhfq068-bib-0001","doi-asserted-by":"crossref","first-page":"H723","DOI":"10.1152\/ajpheart.00555.2003","article-title":"Quantification of left ventricular mechanical dyssynchrony by conductance catheter in heart failure patients","volume":"286","author":"Steendijk","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2026020203341853100_ejhfhfq068-bib-0002","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.ejheart.2008.08.005","article-title":"ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the diagnosis and treatment of acute and chronic heart failure 2008 of the European Society of Cardiology. 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