{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:19:29Z","timestamp":1787008769512,"version":"build-2736575974"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Heart failure and atrial fibrillation (AF) frequently coexist and AF worsens heart failure prognosis. Device-based diagnostics derived from implantable cardioverter-defibrillator (ICD) interrogation provide an accurate method for detecting AF episodes. This study sought to determine clinical and echocardiographic predictors of AF occurrence, including an index of total atrial conduction time derived by tissue Doppler imaging (PA-TDI duration), in patients with heart failure. Moreover, the role of PA-TDI duration on the prediction of AF occurrence in subgroups of patients with and without history of AF was explored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>A cohort of 495 heart failure patients who underwent ICD implantation was studied. Baseline echocardiographic parameters of systolic and diastolic function were evaluated together with clinical parameters. Furthermore, PA-TDI duration was measured. All patients were prospectively followed up after ICD implantation for AF occurrence detected by ICD interrogation. A total of 142 (29%) patients experienced AF over a follow-up period of 16.4 \u00b1 11.2 months. PA-TDI duration was longer in patients with AF occurrence when compared with patients without AF occurrence (154 \u00b1 27 vs. 135 \u00b1 24 ms, P &amp;lt; 0.001). On Cox-multivariable analysis, female gender [hazard ratio = 1.60; 95% confidence intervals (CI) = 1.09\u20132.35; P = 0.017], history of AF (hazard ratio = 2.22; 95% CI, 1.51\u20133.27; P &amp;lt; 0.001), and PA-TDI duration (hazard ratio = 1.27; 95% CI, 1.13\u20131.42; P &amp;lt; 0.001) were independent predictors of AF occurrence. In the subgroups of patients with and without history of AF, PA-TDI duration remained an independent predictor of AF occurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PA-TDI duration may be useful to risk-stratify for AF occurrence in heart failure patients with and without a history of AF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurjhf\/hfq126","type":"journal-article","created":{"date-parts":[[2010,9,22]],"date-time":"2010-09-22T12:48:40Z","timestamp":1285159720000},"page":"1101-1110","source":"Crossref","is-referenced-by-count":36,"title":["Prediction of Atrial Fibrillation in Patients with an Implantable Cardioverter-Defibrillator and Heart Failure"],"prefix":"10.1093","volume":"12","author":[{"given":"Matteo","family":"Bertini","sequence":"first","affiliation":[{"name":"Departments of Cardiology, Leiden University Medical Center , Albinusdreef 2, 2333 ZA, Leiden ,","place":["The Netherlands"]},{"name":"Departments of Cardiology, University of Bologna , Bologna ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Jan Willem","family":"Borleffs","sequence":"additional","affiliation":[{"name":"Departments of Cardiology, Leiden University Medical Center , Albinusdreef 2, 2333 ZA, Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Delgado","sequence":"additional","affiliation":[{"name":"Departments of Cardiology, Leiden University Medical Center , Albinusdreef 2, 2333 ZA, Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnold C.T.","family":"Ng","sequence":"additional","affiliation":[{"name":"Departments of Cardiology, Leiden University Medical Center , Albinusdreef 2, 2333 ZA, Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastiaan R.D.","family":"Piers","sequence":"additional","affiliation":[{"name":"Departments of Cardiology, Leiden University Medical Center , Albinusdreef 2, 2333 ZA, Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Shanks","sequence":"additional","affiliation":[{"name":"Departments of Cardiology, Leiden University Medical Center , Albinusdreef 2, 2333 ZA, Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Louisa","family":"Antoni","sequence":"additional","affiliation":[{"name":"Departments of Cardiology, Leiden University Medical Center , Albinusdreef 2, 2333 ZA, Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Biffi","sequence":"additional","affiliation":[{"name":"Departments of Cardiology, University of Bologna , Bologna ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Boriani","sequence":"additional","affiliation":[{"name":"Departments of Cardiology, University of Bologna , Bologna ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin J.","family":"Schalij","sequence":"additional","affiliation":[{"name":"Departments of Cardiology, Leiden University Medical Center , Albinusdreef 2, 2333 ZA, Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen J.","family":"Bax","sequence":"additional","affiliation":[{"name":"Departments of Cardiology, Leiden University Medical Center , Albinusdreef 2, 2333 ZA, Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nico R.L.","family":"Van de Veire","sequence":"additional","affiliation":[{"name":"Departments of Cardiology, Leiden University Medical Center , Albinusdreef 2, 2333 ZA, Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,1,13]]},"reference":[{"key":"2026020203330100900_ejhfhfq126-bib-0001","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1093\/eurjhf\/hfp085","article-title":"A meta-analysis of the prognostic significance of atrial fibrillation in chronic heart failure","volume":"11","author":"Mamas","year":"2009","journal-title":"Eur J Heart Fail"},{"key":"2026020203330100900_ejhfhfq126-bib-0002","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1161\/01.CIR.98.10.946","article-title":"Impact of atrial fibrillation on the risk of death: the Framingham Heart Study","volume":"98","author":"Benjamin","year":"1998","journal-title":"Circulation"},{"key":"2026020203330100900_ejhfhfq126-bib-0003","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1161\/01.STR.22.8.983","article-title":"Atrial fibrillation as an independent risk factor for stroke: the Framingham Study","volume":"22","author":"Wolf","year":"1991","journal-title":"Stroke"},{"key":"2026020203330100900_ejhfhfq126-bib-0004","doi-asserted-by":"crossref","first-page":"2D","DOI":"10.1016\/S0002-9149(02)03373-8","article-title":"Atrial fibrillation in heart failure: epidemiology, pathophysiology, and rationale for therapy","volume":"91","author":"Maisel","year":"2003","journal-title":"Am J Cardiol"},{"key":"2026020203330100900_ejhfhfq126-bib-0005","first-page":"1979","article-title":"ACC\/AHA\/ESC 2006 guidelines for the management of patients with atrial fibrillation-executive summary: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients with Atrial Fibrillation)","volume":"27","author":"Fuster","year":"2006","journal-title":"Eur Heart J"},{"key":"2026020203330100900_ejhfhfq126-bib-0006","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.ejheart.2008.08.005","article-title":"ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the diagnosis and treatment of acute and chronic heart failure 2008 of the European Society of Cardiology. 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